Quadro P5000 vs Radeon PRO W6600X

NVIDIA

Quadro P5000

2016Core: 1607 MHzBoost: 1733 MHz

Popular choices:

VS
AMD

Radeon PRO W6600X

2021Core: 2068 MHzBoost: 2479 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Quadro P5000

2016

Why buy it

  • 100% more VRAM for high-resolution textures and newer games (16 GB vs 8 GB).

Trade-offs

  • Poor future-proofing: 2016-era hardware with 16 GB of VRAM is already a legacy-tier option for modern games.
  • 257.5% HIGHER MSRP
    $2,499 MSRPvs$699 MSRP
  • Lower G3D Mark per dollar, at 5.1 vs 18.8 G3D/$ ($2,499 MSRP vs $699 MSRP).
  • 50% higher power demand at 180W vs 120W.
  • 10.8% longer card at 267mm vs 241mm.

Radeon PRO W6600X

2021

Why buy it

  • Costs $1,800 less on MSRP ($699 MSRP vs $2,499 MSRP).
  • Delivers 268.3% more G3D Mark for each dollar spent, at 18.8 vs 5.1 G3D/$ ($699 MSRP vs $2,499 MSRP).
  • More future proof: RDNA 2.0 on 7nm with a newer platform for upcoming games.
  • Draws 120W instead of 180W, a 60W reduction.
  • Measures 241mm instead of 267mm, a 26mm shorter card that is more SFF-friendly.

Trade-offs

  • Less VRAM, with 8 GB vs 16 GB for high-resolution textures and newer games.

Quick Answers

So, is Radeon PRO W6600X better than Quadro P5000?
Yes. Radeon PRO W6600X is clearly the better overall GPU here. You are also looking at 13,113 vs 12,728 in G3D Mark. On top of that, Radeon PRO W6600X is a 2021 card with FSR upscaling, while Quadro P5000 is a 2016 model from an older generation with no meaningful modern upscaling stack. So this is not really a tight same-tier comparison. It is more a modern card against an older, weaker alternative.
Which one is more future-proof for 2026 and beyond?
Radeon PRO W6600X is the more future-proof choice for 2026 and beyond. You are getting a newer 2021 generation instead of 2016, better upscaling support with FSR Upscaling / FSR 4 (2025) instead of no meaningful modern upscaling stack, and a 7nm process instead of 16nm. That broader feature stack should age better as more games lean on modern upscaling and frame-generation support.
Which one is the smarter buy today, not just the cheaper card?
Radeon PRO W6600X can still make sense if you find it at the right price, especially around $699 MSRP. Radeon PRO W6600X is still the smarter buy for most people, though, because the raw performance is close while the overall package is cleaner. Radeon PRO W6600X is about $1,800 cheaper on MSRP at $699 MSRP versus $2,499 MSRP, and you are getting 3.0% higher G3D Mark. Moving to $699 MSRP gets you newer hardware, lower power draw (120W vs 180W), and FSR upscaling.
Is Quadro P5000 still worth buying for gaming in 2026?
Yes. Quadro P5000 is still a strong gaming card in 2026: it is very strong for 1080p, good for 1440p, and more limited at 4K. Price is really the swing factor here. If you find it at or below $2,499 MSRP, it remains a very sensible buy. Radeon PRO W6600X is still the safer recommendation for most fresh builds because it offers a cleaner overall package with newer hardware and FSR upscaling.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetQuadro P5000Radeon PRO W6600X
1080p
low252 FPS167 FPS
medium240 FPS148 FPS
high210 FPS131 FPS
ultra172 FPS111 FPS
1440p
low232 FPS140 FPS
medium195 FPS113 FPS
high162 FPS101 FPS
ultra135 FPS91 FPS
4K
low128 FPS84 FPS
medium108 FPS71 FPS
high85 FPS58 FPS
ultra77 FPS50 FPS
Counter-Strike 2

Counter-Strike 2

PresetQuadro P5000Radeon PRO W6600X
1080p
low274 FPS356 FPS
medium231 FPS291 FPS
high171 FPS222 FPS
ultra138 FPS178 FPS
1440p
low180 FPS215 FPS
medium153 FPS179 FPS
high122 FPS141 FPS
ultra98 FPS113 FPS
4K
low105 FPS105 FPS
medium87 FPS87 FPS
high71 FPS74 FPS
ultra55 FPS56 FPS
League of Legends

League of Legends

PresetQuadro P5000Radeon PRO W6600X
1080p
low573 FPS590 FPS
medium458 FPS472 FPS
high382 FPS393 FPS
ultra286 FPS295 FPS
1440p
low430 FPS443 FPS
medium344 FPS354 FPS
high286 FPS295 FPS
ultra215 FPS221 FPS
4K
low286 FPS295 FPS
medium229 FPS236 FPS
high191 FPS197 FPS
ultra143 FPS148 FPS
Valorant

Valorant

PresetQuadro P5000Radeon PRO W6600X
1080p
low442 FPS590 FPS
medium373 FPS472 FPS
high310 FPS393 FPS
ultra260 FPS295 FPS
1440p
low356 FPS443 FPS
medium300 FPS354 FPS
high236 FPS295 FPS
ultra190 FPS221 FPS
4K
low192 FPS293 FPS
medium151 FPS236 FPS
high136 FPS197 FPS
ultra111 FPS148 FPS

Technical Specifications

Side-by-side comparison of Quadro P5000 and Radeon PRO W6600X

NVIDIA

Quadro P5000

The Quadro P5000 is manufactured by NVIDIA. It was released in October 1 2016. It features the Pascal architecture. The core clock ranges from 1607 MHz to 1733 MHz. It has 2048 shading units. The thermal design power (TDP) is 180W. Manufactured using 16 nm process technology. G3D Mark benchmark score: 12,728 points. Launch price was $2,499.

AMD

Radeon PRO W6600X

The Radeon PRO W6600X is manufactured by AMD. It was released in August 3 2021. It features the RDNA 2.0 architecture. The core clock ranges from 2068 MHz to 2479 MHz. It has 2048 shading units. The thermal design power (TDP) is 120W. Manufactured using 7 nm process technology. It features 32 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 13,113 points. Launch price was $699.

Graphics Performance

The Quadro P5000 scores 12,728 and the Radeon PRO W6600X reaches 13,113 in the G3D Mark benchmark — just a 3% difference, making them near-identical in rasterization performance. The Quadro P5000 is built on Pascal while the Radeon PRO W6600X uses RDNA 2.0, both on 16 nm vs 7 nm. Shader units: 2,048 (Quadro P5000) vs 2,048 (Radeon PRO W6600X). Raw compute: 8.873 TFLOPS (Quadro P5000) vs 10.15 TFLOPS (Radeon PRO W6600X). Boost clocks: 1733 MHz vs 2479 MHz.

FeatureQuadro P5000Radeon PRO W6600X
G3D Mark Score
12,728
13,113+3%
Architecture
Pascal
RDNA 2.0
Process Node
16 nm
7 nm
Shading Units
2048
2048
Compute (TFLOPS)
8.873 TFLOPS
10.15 TFLOPS+14%
Boost Clock
1733 MHz
2479 MHz+43%
ROPs
64
64
TMUs
160+25%
128
L1 Cache
960 KB+88%
512 KB
L2 Cache
2 MB
2 MB

Advanced Features (DLSS/FSR)

FeatureQuadro P5000Radeon PRO W6600X
Upscaling Tech
Upscaling support
FSR Upscaling / FSR 4
Frame Generation
Not Supported
Not Supported
Ray Reconstruction
No
No
Low Latency
Standard
AMD Anti-Lag
💾

Video Memory (VRAM)

The Quadro P5000 comes with 16 GB of VRAM, while the Radeon PRO W6600X has 8 GB. The Quadro P5000 offers 100% more capacity, crucial for higher resolutions and texture-heavy games. Memory bandwidth: 288 GB/s (Quadro P5000) vs 224 GB/s (Radeon PRO W6600X) — a 28.6% advantage for the Quadro P5000. Bus width: 256-bit vs 256-bit.

FeatureQuadro P5000Radeon PRO W6600X
VRAM Capacity
16 GB+100%
8 GB
Memory Type
GDDR5X
GDDR6
Memory Bandwidth
288 GB/s+29%
224 GB/s
Bus Width
256-bit
256-bit
L2 Cache
2 MB
2 MB
🖥️

Display & API Support

DirectX support: 12.1 (Quadro P5000) vs 12.2 (Radeon PRO W6600X). Vulkan: 1.0 vs 1.3. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 4.

FeatureQuadro P5000Radeon PRO W6600X
DirectX
12.1
12.2
Vulkan
1.0
1.3+30%
OpenGL
4.6
4.6
Max Displays
4
4
🎬

Media & Encoding

Hardware encoder: 6th Gen NVENC (Quadro P5000) vs VCN 3.0 (Radeon PRO W6600X). Decoder: 3rd Gen NVDEC vs VCN 3.0. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro P5000) vs MPEG-2,H.264,HEVC,VP9,AV1 (Radeon PRO W6600X).

FeatureQuadro P5000Radeon PRO W6600X
Encoder
6th Gen NVENC
VCN 3.0
Decoder
3rd Gen NVDEC
VCN 3.0
Codecs
MPEG-2,H.264,HEVC,VP9
MPEG-2,H.264,HEVC,VP9,AV1
🔌

Power & Dimensions

The Quadro P5000 draws 180W versus the Radeon PRO W6600X's 120W — a 40% difference. The Radeon PRO W6600X is more power-efficient. Recommended PSU: 500W (Quadro P5000) vs 500W (Radeon PRO W6600X). Power connectors: PCIe-powered vs PCIe-powered. Card length: 267mm vs 241mm, occupying 2 vs 2 slots. Typical load temperature: 80°C vs 75°C.

FeatureQuadro P5000Radeon PRO W6600X
TDP
180W
120W-33%
Recommended PSU
500W
500W
Power Connector
PCIe-powered
PCIe-powered
Length
267mm
241mm
Height
111mm
111mm
Slots
2
2
Temp (Load)
80°C
75°C-6%
Perf/Watt
70.7
109.3+55%
💰

Value Analysis

The Quadro P5000 launched at $2499 MSRP, while the Radeon PRO W6600X launched at $699. The Radeon PRO W6600X costs 72% less ($1800 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 5.1 (Quadro P5000) vs 18.8 (Radeon PRO W6600X) — the Radeon PRO W6600X offers 268.6% better value. The Radeon PRO W6600X is the newer GPU (2021 vs 2016).

FeatureQuadro P5000Radeon PRO W6600X
MSRP
$2499
$699-72%
Performance per Dollar
5.1
18.8+269%
Codename
GP104
Navi 23
Release
October 1 2016
August 3 2021
Ranking
#206
#197