Quadro P5000 vs Radeon Pro Vega 64

NVIDIA

Quadro P5000

2016Core: 1607 MHzBoost: 1733 MHz

Popular choices:

VS
AMD

Radeon Pro Vega 64

2017Core: 1250 MHzBoost: 1350 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Quadro P5000

2016

Why buy it

  • 100+% more VRAM for high-resolution textures and newer games (16 GB vs Unknown).
  • Less risky long-term buy than Radeon Pro Vega 64: it remains the more sensible modern option while Radeon Pro Vega 64 is already obsolete for modern gaming.
  • Draws 180W instead of 250W, a 70W reduction.

Trade-offs

  • Poor future-proofing: 2016-era hardware with 16 GB of VRAM is already a legacy-tier option for modern games.
  • 317.2% HIGHER MSRP
    $2,499 MSRPvs$599 MSRP
  • Lower G3D Mark per dollar, at 5.1 vs 21.5 G3D/$ ($2,499 MSRP vs $599 MSRP).

Radeon Pro Vega 64

2017

Why buy it

  • Costs $1,900 less on MSRP ($599 MSRP vs $2,499 MSRP).
  • Delivers 322.5% more G3D Mark for each dollar spent, at 21.5 vs 5.1 G3D/$ ($599 MSRP vs $2,499 MSRP).
  • More future proof: GCN 5.0 (2017−2020) on 14nm with a newer platform for upcoming games.

Trade-offs

  • Less VRAM, with Unknown vs 16 GB for high-resolution textures and newer games.
  • Very weak future-proofing: 2017-era hardware with Unknown of VRAM is already obsolete for modern gaming and is hard to recommend today.
  • 38.9% higher power demand at 250W vs 180W.

Quick Answers

So, is Radeon Pro Vega 64 better than Quadro P5000?
Yes. Radeon Pro Vega 64 is clearly the better overall GPU here. You are also looking at 12,891 vs 12,728 in G3D Mark. On top of that, Radeon Pro Vega 64 is a 2017 card with FSR upscaling, while Quadro P5000 is a 2016 model from an older generation with no meaningful modern upscaling stack. So this is not really a tight same-tier comparison. It is more a modern card against an older, weaker alternative.
Which one is more future-proof for 2026 and beyond?
Quadro P5000 is the more future-proof choice for 2026 and beyond. You are getting more VRAM at 16 GB instead of Unknown and the stronger feature stack with no meaningful modern upscaling stack instead of FSR upscaling. That extra memory headroom makes it the safer pick for newer games, heavier textures, and higher settings over time.
Which one is the smarter buy today, not just the cheaper card?
Radeon Pro Vega 64 can still make sense if you find it at the right price, especially around $599 MSRP. Radeon Pro Vega 64 is still the smarter buy for most people, though, because the raw performance is close while the overall package is cleaner. Radeon Pro Vega 64 is about $1,900 cheaper on MSRP at $599 MSRP versus $2,499 MSRP, and you are getting 1.3% higher G3D Mark. Quadro P5000 is the more forward-looking alternative, so it still has a real case if you care more about lower power draw (180W vs 250W) and future-proofing than about squeezing out the strongest gaming value today.
When does Quadro P5000 make more sense than Radeon Pro Vega 64?
Yes. Quadro P5000 is still an excellent gaming GPU in 2026: it is very strong for 1080p, good for 1440p, and more limited at 4K. It makes more sense if your priority is lower power draw (180W vs 250W), future-proofing, and staying closer to $2,499 MSRP more than squeezing out the extra headroom of Radeon Pro Vega 64. The trade-off is that Radeon Pro Vega 64 currently gives you 1.3% higher G3D Mark. It also leads G3D-per-dollar by 322.5%.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetQuadro P5000Radeon Pro Vega 64
1080p
low252 FPS106 FPS
medium240 FPS96 FPS
high210 FPS81 FPS
ultra172 FPS67 FPS
1440p
low232 FPS94 FPS
medium195 FPS81 FPS
high162 FPS65 FPS
ultra135 FPS55 FPS
4K
low128 FPS47 FPS
medium108 FPS42 FPS
high85 FPS32 FPS
ultra77 FPS29 FPS
Counter-Strike 2

Counter-Strike 2

PresetQuadro P5000Radeon Pro Vega 64
1080p
low274 FPS301 FPS
medium231 FPS262 FPS
high171 FPS203 FPS
ultra138 FPS164 FPS
1440p
low180 FPS204 FPS
medium153 FPS175 FPS
high122 FPS144 FPS
ultra98 FPS114 FPS
4K
low105 FPS100 FPS
medium87 FPS84 FPS
high71 FPS71 FPS
ultra55 FPS56 FPS
League of Legends

League of Legends

PresetQuadro P5000Radeon Pro Vega 64
1080p
low573 FPS580 FPS
medium458 FPS464 FPS
high382 FPS387 FPS
ultra286 FPS290 FPS
1440p
low430 FPS435 FPS
medium344 FPS348 FPS
high286 FPS290 FPS
ultra215 FPS218 FPS
4K
low286 FPS290 FPS
medium229 FPS232 FPS
high191 FPS193 FPS
ultra143 FPS145 FPS
Valorant

Valorant

PresetQuadro P5000Radeon Pro Vega 64
1080p
low442 FPS300 FPS
medium373 FPS247 FPS
high310 FPS215 FPS
ultra260 FPS170 FPS
1440p
low356 FPS220 FPS
medium300 FPS182 FPS
high236 FPS154 FPS
ultra190 FPS122 FPS
4K
low192 FPS132 FPS
medium151 FPS118 FPS
high136 FPS100 FPS
ultra111 FPS79 FPS

Technical Specifications

Side-by-side comparison of Quadro P5000 and Radeon Pro Vega 64

NVIDIA

Quadro P5000

The Quadro P5000 is manufactured by NVIDIA. It was released in October 1 2016. It features the Pascal architecture. The core clock ranges from 1607 MHz to 1733 MHz. It has 2048 shading units. The thermal design power (TDP) is 180W. Manufactured using 16 nm process technology. G3D Mark benchmark score: 12,728 points. Launch price was $2,499.

AMD

Radeon Pro Vega 64

The Radeon Pro Vega 64 is manufactured by AMD. It was released in June 27 2017. It features the GCN 5.0 architecture. The core clock ranges from 1250 MHz to 1350 MHz. It has 4096 shading units. The thermal design power (TDP) is 250W. Manufactured using 14 nm process technology. G3D Mark benchmark score: 12,891 points.

Graphics Performance

The Quadro P5000 scores 12,728 and the Radeon Pro Vega 64 reaches 12,891 in the G3D Mark benchmark — just a 1.3% difference, making them near-identical in rasterization performance. The Quadro P5000 is built on Pascal while the Radeon Pro Vega 64 uses GCN 5.0, both on 16 nm vs 14 nm. Shader units: 2,048 (Quadro P5000) vs 4,096 (Radeon Pro Vega 64). Raw compute: 8.873 TFLOPS (Quadro P5000) vs 11.06 TFLOPS (Radeon Pro Vega 64). Boost clocks: 1733 MHz vs 1350 MHz.

FeatureQuadro P5000Radeon Pro Vega 64
G3D Mark Score
12,728
12,891+1%
Architecture
Pascal
GCN 5.0
Process Node
16 nm
14 nm
Shading Units
2048
4096+100%
Compute (TFLOPS)
8.873 TFLOPS
11.06 TFLOPS+25%
Boost Clock
1733 MHz+28%
1350 MHz
ROPs
64
64
TMUs
160
256+60%
L1 Cache
0.94 MB
1 MB+6%
L2 Cache
2 MB
4 MB+100%

Advanced Features (DLSS/FSR)

FeatureQuadro P5000Radeon Pro Vega 64
Upscaling Tech
Upscaling support
FSR Upscaling / FSR 4
Frame Generation
Not Supported
Not Supported
Ray Reconstruction
No
No
Low Latency
Standard
AMD Anti-Lag
💾

Video Memory (VRAM)

The Quadro P5000 comes with 16 GB of VRAM, while the Radeon Pro Vega 64 has 0 MB. The Quadro P5000 offers 100+% more capacity, crucial for higher resolutions and texture-heavy games. Bus width: 256-bit vs 128-bit. L2 Cache: 2 MB (Quadro P5000) vs 4 MB (Radeon Pro Vega 64) — the Radeon Pro Vega 64 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro P5000Radeon Pro Vega 64
VRAM Capacity
16 GB
Shared System RAM
Memory Type
GDDR5X
GDDR6
Bus Width
256-bit+100%
128-bit
L2 Cache
2 MB
4 MB+100%
🖥️

Display & API Support

DirectX support: 12.1 (Quadro P5000) vs 12.1 (Radeon Pro Vega 64). Vulkan: 1.0 vs 1.1. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 4.

FeatureQuadro P5000Radeon Pro Vega 64
DirectX
12.1
12.1
Vulkan
1.0
1.1+10%
OpenGL
4.6
4.6
Max Displays
4
4
🎬

Media & Encoding

Hardware encoder: 6th Gen NVENC (Quadro P5000) vs VCE 4.0 (Radeon Pro Vega 64). Decoder: 3rd Gen NVDEC vs UVD 7.0. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro P5000) vs MPEG-2,H.264,HEVC,VP9 (Radeon Pro Vega 64).

FeatureQuadro P5000Radeon Pro Vega 64
Encoder
6th Gen NVENC
VCE 4.0
Decoder
3rd Gen NVDEC
UVD 7.0
Codecs
MPEG-2,H.264,HEVC,VP9
MPEG-2,H.264,HEVC,VP9
🔌

Power & Dimensions

The Quadro P5000 draws 180W versus the Radeon Pro Vega 64's 250W — a 32.6% difference. The Quadro P5000 is more power-efficient. Recommended PSU: 500W (Quadro P5000) vs 1W (Radeon Pro Vega 64). Power connectors: PCIe-powered vs Integrated. Card length: 267mm vs 267mm, occupying 2 vs 2 slots. Typical load temperature: 80°C vs 85°C.

FeatureQuadro P5000Radeon Pro Vega 64
TDP
180W-28%
250W
Recommended PSU
500W
1W-100%
Power Connector
PCIe-powered
Integrated
Length
267mm
267mm
Height
111mm
111mm
Slots
2
2
Temp (Load)
80°C-6%
85°C
Perf/Watt
70.7+37%
51.6
💰

Value Analysis

The Quadro P5000 launched at $2499 MSRP, while the Radeon Pro Vega 64 launched at $599. The Radeon Pro Vega 64 costs 76% less ($1900 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 5.1 (Quadro P5000) vs 21.5 (Radeon Pro Vega 64) — the Radeon Pro Vega 64 offers 321.6% better value. The Radeon Pro Vega 64 is the newer GPU (2017 vs 2016).

FeatureQuadro P5000Radeon Pro Vega 64
MSRP
$2499
$599-76%
Performance per Dollar
5.1
21.5+322%
Codename
GP104
Vega 10
Release
October 1 2016
June 27 2017
Ranking
#206
#202