EPYC 7543P vs EPYC 7573X

AMD

EPYC 7543P

32 Cores64 Thrd225 WWMax: 3.7 GHz2021

Popular choices:

VS
AMD

EPYC 7573X

32 Cores64 Thrd280 WWMax: 3.6 GHz2022

Popular choices:

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

EPYC 7543P

2021

Why buy it

  • Costs $2,860 less on MSRP ($2,730 MSRP vs $5,590 MSRP).
  • Delivers 96.4% more PassMark for each dollar spent, at 24.4 vs 12.4 PassMark/$ ($2,730 MSRP vs $5,590 MSRP).
  • Draws 225W instead of 280W, a 55W reduction.

Trade-offs

  • Lower PassMark (66,590 vs 69,432).
  • Smaller total L3 cache (256 MB vs 768 MB).

EPYC 7573X

2022

Why buy it

  • +4.3% higher PassMark.
  • +200% larger total L3 cache (768 MB vs 256 MB).

Trade-offs

  • Lower PassMark per dollar, at 12.4 vs 24.4 PassMark/$ ($5,590 MSRP vs $2,730 MSRP).
  • 24.4% higher power demand at 280W vs 225W.

Quick Answers

So, is EPYC 7543P better than EPYC 7573X?
It depends on what matters more to you. For gaming, EPYC 7543P is ahead with a 0.9% average FPS lead across 4 shared CPU game tests in our data. For rendering, compiling, streaming, and heavier multitasking, EPYC 7573X pulls ahead with 4.3% better PassMark. EPYC 7573X also has the bigger cache pool with 200% larger total L3 cache (768 MB vs 256 MB).
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, EPYC 7573X is the better fit. You are getting 4.3% better PassMark, backed by 32 cores and 64 threads. It also carries the larger cache pool with 200% larger total L3 cache (768 MB vs 256 MB).
Which one is the smarter buy today, not just the cheaper CPU?
EPYC 7543P is the smarter buy today. EPYC 7543P is $2,860 cheaper on MSRP at $2,730 MSRP versus $5,590 MSRP, and it gives you a 0.9% average FPS lead across 4 shared CPU game tests in our data. The trade-off is that EPYC 7573X is still stronger for heavier multi-core work with 4.3% better PassMark. It is also 96.4% better value on MSRP (24.4 vs 12.4 PassMark/$), so the better CPU is not just faster, it is also the cleaner value play on paper.
Which one is more future-proof for 2026 and beyond?
EPYC 7573X is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2022 vs 2021), 200% larger total L3 cache (768 MB vs 256 MB), and more multi-core headroom with 32 cores / 64 threads instead of 32/64. That extra cache should hold up really well in CPU-limited games and high-refresh builds.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Path of Exile 2

Path of Exile 2

PresetEPYC 7543PEPYC 7573X
1080p
low198 FPS205 FPS
medium161 FPS167 FPS
high129 FPS136 FPS
ultra100 FPS105 FPS
1440p
low161 FPS163 FPS
medium126 FPS127 FPS
high98 FPS100 FPS
ultra78 FPS79 FPS
4K
low73 FPS74 FPS
medium61 FPS61 FPS
high47 FPS48 FPS
ultra39 FPS40 FPS
Counter-Strike 2

Counter-Strike 2

PresetEPYC 7543PEPYC 7573X
1080p
low507 FPS463 FPS
medium443 FPS407 FPS
high354 FPS329 FPS
ultra288 FPS259 FPS
1440p
low417 FPS381 FPS
medium373 FPS343 FPS
high308 FPS286 FPS
ultra243 FPS218 FPS
4K
low257 FPS234 FPS
medium234 FPS215 FPS
high205 FPS180 FPS
ultra171 FPS144 FPS
League of Legends

League of Legends

PresetEPYC 7543PEPYC 7573X
1080p
low850 FPS865 FPS
medium705 FPS717 FPS
high657 FPS668 FPS
ultra580 FPS590 FPS
1440p
low612 FPS622 FPS
medium506 FPS514 FPS
high464 FPS472 FPS
ultra405 FPS412 FPS
4K
low437 FPS444 FPS
medium339 FPS345 FPS
high303 FPS308 FPS
ultra245 FPS249 FPS
Valorant

Valorant

PresetEPYC 7543PEPYC 7573X
1080p
low992 FPS992 FPS
medium900 FPS900 FPS
high775 FPS775 FPS
ultra671 FPS671 FPS
1440p
low763 FPS767 FPS
medium665 FPS668 FPS
high569 FPS572 FPS
ultra490 FPS492 FPS
4K
low547 FPS550 FPS
medium488 FPS490 FPS
high428 FPS430 FPS
ultra370 FPS372 FPS

Technical Specifications

Side-by-side comparison of EPYC 7543P and EPYC 7573X

AMD

EPYC 7543P

The EPYC 7543P is manufactured by AMD. It was released in 15 March 2021 (4 years ago). It is based on the Milan (2021−2023) architecture. It features 32 cores and 64 threads. Base frequency is 2.8 GHz, with boost up to 3.7 GHz. L3 cache: 256 MB (total). L2 cache: 512 kB (per core). Built on 7 nm+ process technology. Socket: SP3. Thermal design power (TDP): 225 Watt. Memory support: DDR4-3200. Passmark benchmark score: 66,590 points. Launch price was $2,730.

AMD

EPYC 7573X

The EPYC 7573X is manufactured by AMD. It was released in 2022-03-01. It is based on the Milan-X (2022) architecture. It features 32 cores and 64 threads. Base frequency is 2.8 GHz, with boost up to 3.6 GHz. L3 cache: 768 MB (total). L2 cache: 512K (per core). Built on 7 nm process technology. Socket: SP3. Thermal design power (TDP): 280 Watt. Memory support: DDR4-3200. Passmark benchmark score: 69,432 points. Launch price was $5,590.

Processing Power

Both the EPYC 7543P and EPYC 7573X share an identical 32-core/64-thread configuration. Boost clocks reach 3.7 GHz on the EPYC 7543P versus 3.6 GHz on the EPYC 7573X — a 2.7% clock advantage for the EPYC 7543P (base: 2.8 GHz vs 2.8 GHz). The EPYC 7543P uses the Milan (2021−2023) architecture (7 nm+), while the EPYC 7573X uses Milan-X (2022) (7 nm). In PassMark, the EPYC 7543P scores 66,590 against the EPYC 7573X's 69,432 — a 4.2% lead for the EPYC 7573X. L3 cache: 256 MB (total) on the EPYC 7543P vs 768 MB (total) on the EPYC 7573X.

FeatureEPYC 7543PEPYC 7573X
Cores / Threads
32 / 64
32 / 64
Boost Clock
3.7 GHz+3%
3.6 GHz
Base Clock
2.8 GHz
2.8 GHz
L3 Cache
256 MB (total)
768 MB (total)+200%
L2 Cache
512 kB (per core)
512K (per core)
Process
7 nm+
7 nm
Architecture
Milan (2021−2023)
Milan-X (2022)
PassMark
66,590
69,432+4%
🧠

Memory & Platform

Both processors use the SP3 socket with PCIe 4.0. Both support up to 3200 memory speed. Both support up to 4096 of RAM. Both feature 8-channel memory with ECC support. Both provide 128 PCIe lanes. Chipset compatibility: SP3 (EPYC 7543P) and SP3 (EPYC 7573X).

FeatureEPYC 7543PEPYC 7573X
Socket
SP3
SP3
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
3200
3200
Max RAM Capacity
4096
4096
RAM Channels
8
8
ECC Support
Yes
Yes
PCIe Lanes
128
128
🔧

Advanced Features

Neither processor supports overclocking. Both support VT-x, VT-d virtualization. Direct competitor: EPYC 7543P rivals Xeon Platinum 8380; EPYC 7573X rivals Xeon Platinum 8280.

FeatureEPYC 7543PEPYC 7573X
Integrated GPU
No
No
IGPU Model
None
None
Unlocked
No
No
AVX-512
No
No
Virtualization
VT-x, VT-d
VT-x, VT-d
💰

Value Analysis

The EPYC 7543P launched at $2730 MSRP, while the EPYC 7573X debuted at $5590. On MSRP ($2730 vs $5590), the EPYC 7543P is $2860 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 7543P delivers 24.4 pts/$ vs 12.4 pts/$ for the EPYC 7573X — making the EPYC 7543P the 65% better value option.

FeatureEPYC 7543PEPYC 7573X
MSRP
$2730-51%
$5590
Performance per Dollar
24.4+97%
12.4
Release Date
2021
2022