Radeon PRO W6400 vs Radeon RX 480

AMD

Radeon PRO W6400

2022Core: 2331 MHzBoost: 2331 MHz

Popular choices:

VS
AMD

Radeon RX 480

2016Core: 1120 MHzBoost: 1266 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Radeon PRO W6400

2022

Why buy it

  • More future proof: RDNA 2.0 (2020−2025) on 6nm with a newer platform for upcoming games.
  • Draws 50W instead of 150W, a 100W reduction.
  • Measures 168mm instead of 240mm, a 72mm shorter card that is more SFF-friendly.

Trade-offs

  • Less VRAM, with 4 GB vs 8 GB for high-resolution textures and newer games.

Radeon RX 480

2016

Why buy it

  • 100% more VRAM for high-resolution textures and newer games (8 GB vs 4 GB).

Trade-offs

  • Poor future-proofing: 2016-era hardware with 8 GB of VRAM is already a legacy-tier option for modern games.
  • 200% higher power demand at 150W vs 50W.
  • 42.9% longer card at 240mm vs 168mm.

Quick Answers

So, is Radeon RX 480 better than Radeon PRO W6400?
Yes. Radeon RX 480 is clearly the better overall GPU here. You are also looking at 8,546 vs 8,428 in G3D Mark. On top of that, Radeon RX 480 is a 2016 card with FSR upscaling, while Radeon PRO W6400 is a 2022 model from an older generation with FSR upscaling. So this is not really a tight same-tier comparison. It is more a modern card against an older, weaker alternative.
Which one is more future-proof for 2026 and beyond?
Radeon PRO W6400 is the more future-proof choice for 2026 and beyond. You are getting a newer 2022 generation instead of 2016, 100.0% more ray-tracing hardware, and a 6nm process instead of 14nm. That makes it the safer long-run choice for modern games.
Which one is the smarter buy today, not just the cheaper card?
Radeon RX 480 is the smarter buy by a wide margin. Radeon RX 480 is in basically the same MSRP band at $229 MSRP versus $229 MSRP, and you are getting 1.4% higher G3D Mark. Radeon PRO W6400 really only makes sense now as a very cheap stopgap or a used-market placeholder.
When does Radeon PRO W6400 make more sense than Radeon RX 480?
Yes. Radeon PRO W6400 is still an excellent gaming GPU in 2026: it is still comfortable for 1080p and decent for 1440p, though 4K is more situational. It makes more sense if your priority is newer architecture, lower power draw (50W vs 150W), future-proofing, and staying closer to $229 MSRP more than squeezing out the extra headroom of Radeon RX 480. The trade-off is that Radeon RX 480 currently gives you 1.4% higher G3D Mark. It only holds a slight 1.4% edge in G3D-per-dollar, so the value lead is real but narrow.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetRadeon PRO W6400Radeon RX 480
1080p
low132 FPS134 FPS
medium118 FPS113 FPS
high101 FPS97 FPS
ultra75 FPS58 FPS
1440p
low118 FPS114 FPS
medium100 FPS96 FPS
high83 FPS72 FPS
ultra62 FPS42 FPS
4K
low49 FPS39 FPS
medium46 FPS36 FPS
high34 FPS23 FPS
ultra30 FPS19 FPS
Counter-Strike 2

Counter-Strike 2

PresetRadeon PRO W6400Radeon RX 480
1080p
low165 FPS156 FPS
medium130 FPS135 FPS
high97 FPS115 FPS
ultra63 FPS89 FPS
1440p
low108 FPS91 FPS
medium85 FPS71 FPS
high64 FPS56 FPS
ultra45 FPS44 FPS
4K
low56 FPS37 FPS
medium44 FPS29 FPS
high35 FPS23 FPS
ultra22 FPS18 FPS
League of Legends

League of Legends

PresetRadeon PRO W6400Radeon RX 480
1080p
low377 FPS385 FPS
medium303 FPS308 FPS
high249 FPS256 FPS
ultra190 FPS192 FPS
1440p
low265 FPS288 FPS
medium228 FPS231 FPS
high186 FPS192 FPS
ultra142 FPS144 FPS
4K
low155 FPS192 FPS
medium143 FPS154 FPS
high102 FPS128 FPS
ultra70 FPS96 FPS
Valorant

Valorant

PresetRadeon PRO W6400Radeon RX 480
1080p
low285 FPS290 FPS
medium206 FPS252 FPS
high180 FPS210 FPS
ultra146 FPS166 FPS
1440p
low210 FPS213 FPS
medium149 FPS190 FPS
high132 FPS153 FPS
ultra104 FPS118 FPS
4K
low105 FPS120 FPS
medium76 FPS98 FPS
high67 FPS80 FPS
ultra51 FPS62 FPS

Technical Specifications

Side-by-side comparison of Radeon PRO W6400 and Radeon RX 480

AMD

Radeon PRO W6400

The Radeon PRO W6400 is manufactured by AMD. It was released in January 19 2022. It features the RDNA 2.0 architecture. The core clock ranges from 2331 MHz to 2331 MHz. It has 768 shading units. The thermal design power (TDP) is 50W. Manufactured using 6 nm process technology. It features 12 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 8,428 points.

AMD

Radeon RX 480

The Radeon RX 480 is manufactured by AMD. It was released in June 29 2016. It features the GCN 4.0 architecture. The core clock ranges from 1120 MHz to 1266 MHz. It has 2304 shading units. The thermal design power (TDP) is 150W. Manufactured using 14 nm process technology. G3D Mark benchmark score: 8,546 points. Launch price was $229.

Graphics Performance

The Radeon PRO W6400 scores 8,428 and the Radeon RX 480 reaches 8,546 in the G3D Mark benchmark — just a 1.4% difference, making them near-identical in rasterization performance. The Radeon PRO W6400 is built on RDNA 2.0 while the Radeon RX 480 uses GCN 4.0, both on 6 nm vs 14 nm. Shader units: 768 (Radeon PRO W6400) vs 2,304 (Radeon RX 480). Raw compute: 3.58 TFLOPS (Radeon PRO W6400) vs 5.834 TFLOPS (Radeon RX 480). Boost clocks: 2331 MHz vs 1266 MHz.

FeatureRadeon PRO W6400Radeon RX 480
G3D Mark Score
8,428
8,546+1%
Architecture
RDNA 2.0
GCN 4.0
Process Node
6 nm
14 nm
Shading Units
768
2304+200%
Compute (TFLOPS)
3.58 TFLOPS
5.834 TFLOPS+63%
Boost Clock
2331 MHz+84%
1266 MHz
ROPs
32
32
TMUs
48
144+200%
L1 Cache
256 KB
576 KB+125%
L2 Cache
1 MB
2 MB+100%
Frame Generation
FSR upscaling + RSR
FSR upscaling

Advanced Features (DLSS/FSR)

FeatureRadeon PRO W6400Radeon RX 480
Upscaling Tech
FSR Upscaling / FSR 4
FSR Upscaling / FSR 4
Frame Generation
Not Supported
Not Supported
Ray Reconstruction
No
No
Low Latency
AMD Anti-Lag
AMD Anti-Lag
💾

Video Memory (VRAM)

The Radeon PRO W6400 comes with 4 GB of VRAM, while the Radeon RX 480 has 8 GB. The Radeon RX 480 offers 100% more capacity, crucial for higher resolutions and texture-heavy games. Bus width: 256-bit vs 256-bit. L2 Cache: 1 MB (Radeon PRO W6400) vs 2 MB (Radeon RX 480) — the Radeon RX 480 has significantly larger on-die cache to reduce VRAM reliance.

FeatureRadeon PRO W6400Radeon RX 480
VRAM Capacity
4 GB
8 GB+100%
Memory Type
GDDR6
GDDR5
Bus Width
256-bit
256-bit
L2 Cache
1 MB
2 MB+100%
🖥️

Display & API Support

DirectX support: 12.2 (Radeon PRO W6400) vs 12.0 (Radeon RX 480). Vulkan: 1.2 vs 1.3. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 2 vs 4.

FeatureRadeon PRO W6400Radeon RX 480
DirectX
12.2+2%
12.0
Vulkan
1.2
1.3+8%
OpenGL
4.6
4.6
Max Displays
2
4+100%
🎬

Media & Encoding

Hardware encoder: VCN 3.0 (Radeon PRO W6400) vs VCE 3.4 (Radeon RX 480). Decoder: VCN 3.0 vs UVD 6.3. Supported codecs: MPEG-2,H.264,HEVC,VP9,AV1 (Decode) (Radeon PRO W6400) vs MPEG-2,H.264,HEVC (Radeon RX 480).

FeatureRadeon PRO W6400Radeon RX 480
Encoder
VCN 3.0
VCE 3.4
Decoder
VCN 3.0
UVD 6.3
Codecs
MPEG-2,H.264,HEVC,VP9,AV1 (Decode)
MPEG-2,H.264,HEVC
🔌

Power & Dimensions

The Radeon PRO W6400 draws 50W versus the Radeon RX 480's 150W — a 100% difference. The Radeon PRO W6400 is more power-efficient. Recommended PSU: 500W (Radeon PRO W6400) vs 500W (Radeon RX 480). Power connectors: PCIe-powered vs 8-pin. Card length: 168mm vs 240mm, occupying 1 vs 2 slots. Typical load temperature: 70°C vs 85°C.

FeatureRadeon PRO W6400Radeon RX 480
TDP
50W-67%
150W
Recommended PSU
500W
500W
Power Connector
PCIe-powered
8-pin
Length
168mm
240mm
Height
69mm
95mm
Slots
1-50%
2
Temp (Load)
70°C-18%
85°C
Perf/Watt
168.6+196%
57.0
💰

Value Analysis

The Radeon PRO W6400 launched at $229 MSRP, while the Radeon RX 480 launched at $229. Performance per dollar on MSRP (G3D Mark / MSRP): 36.8 (Radeon PRO W6400) vs 37.3 (Radeon RX 480) — the Radeon RX 480 offers 1.4% better value. The Radeon PRO W6400 is the newer GPU (2022 vs 2016).

FeatureRadeon PRO W6400Radeon RX 480
MSRP
$229
$229
Performance per Dollar
36.8
37.3+1%
Codename
Navi 24
Ellesmere
Release
January 19 2022
June 29 2016
Ranking
#308
#305