Radeon PRO W6400 vs Radeon R9 295X2

AMD

Radeon PRO W6400

2022Core: 2331 MHzBoost: 2331 MHz

Popular choices:

VS
AMD

Radeon R9 295X2

2014Boost: 1018 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Radeon PRO W6400

2022

Why buy it

  • Costs $1,270 less on MSRP ($229 MSRP vs $1,499 MSRP).
  • Delivers 531.7% more G3D Mark for each dollar spent, at 36.8 vs 5.8 G3D/$ ($229 MSRP vs $1,499 MSRP).
  • More future proof: RDNA 2.0 (2020−2025) on 6nm with a newer platform for upcoming games.
  • Draws 50W instead of 500W, a 450W reduction.
  • Measures 168mm instead of 307mm, a 139mm shorter card that is more SFF-friendly.

Trade-offs

  • Less VRAM, with 4 GB vs 8 GB for high-resolution textures and newer games.

Radeon R9 295X2

2014

Why buy it

  • 100% more VRAM for high-resolution textures and newer games (8 GB vs 4 GB).

Trade-offs

  • Poor future-proofing: 2014-era hardware with 8 GB of VRAM is already a legacy-tier option for modern games.
  • 554.6% HIGHER MSRP
    $1,499 MSRPvs$229 MSRP
  • Lower G3D Mark per dollar, at 5.8 vs 36.8 G3D/$ ($1,499 MSRP vs $229 MSRP).
  • 900% higher power demand at 500W vs 50W.
  • 82.7% longer card at 307mm vs 168mm.

Quick Answers

So, is Radeon R9 295X2 better than Radeon PRO W6400?
Yes. Radeon R9 295X2 is clearly the better overall GPU here. You are also looking at 8,734 vs 8,428 in G3D Mark. On top of that, Radeon R9 295X2 is a 2014 card with FSR upscaling, while Radeon PRO W6400 is a 2022 model from an older generation with FSR upscaling. So this is not really a tight same-tier comparison. It is more a modern card against an older, weaker alternative.
Which one is more future-proof for 2026 and beyond?
Radeon PRO W6400 is the more future-proof choice for 2026 and beyond. You are getting a newer 2022 generation instead of 2014, 100.0% more ray-tracing hardware, and a 6nm process instead of 28nm. That makes it the safer long-run choice for modern games.
Which one is the smarter buy today, not just the cheaper card?
Radeon R9 295X2 is the smarter buy by a wide margin. Radeon R9 295X2 is about 554.6% more expensive on MSRP at $1,499 MSRP versus $229 MSRP, and you are getting 3.6% higher G3D Mark. Radeon PRO W6400 really only makes sense now as a very cheap stopgap or a used-market placeholder.
When does Radeon PRO W6400 make more sense than Radeon R9 295X2?
Yes. Radeon PRO W6400 is still an excellent gaming GPU in 2026: it is still comfortable for 1080p and decent for 1440p, though 4K is more situational. It makes more sense if your priority is newer architecture, lower power draw (50W vs 500W), future-proofing, and staying closer to $229 MSRP more than squeezing out the extra headroom of Radeon R9 295X2. The trade-off is that Radeon R9 295X2 currently gives you 3.6% higher G3D Mark. Radeon PRO W6400 still holds the G3D-per-dollar lead, so the performance win comes with a real value premium.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetRadeon PRO W6400Radeon R9 295X2
1080p
low132 FPS105 FPS
medium118 FPS89 FPS
high101 FPS73 FPS
ultra75 FPS49 FPS
1440p
low118 FPS89 FPS
medium100 FPS75 FPS
high83 FPS55 FPS
ultra62 FPS36 FPS
4K
low49 FPS36 FPS
medium46 FPS32 FPS
high34 FPS20 FPS
ultra30 FPS17 FPS
Counter-Strike 2

Counter-Strike 2

PresetRadeon PRO W6400Radeon R9 295X2
1080p
low169 FPS193 FPS
medium134 FPS169 FPS
high99 FPS141 FPS
ultra66 FPS110 FPS
1440p
low110 FPS137 FPS
medium86 FPS111 FPS
high64 FPS88 FPS
ultra46 FPS68 FPS
4K
low57 FPS63 FPS
medium44 FPS53 FPS
high35 FPS48 FPS
ultra22 FPS39 FPS
League of Legends

League of Legends

PresetRadeon PRO W6400Radeon R9 295X2
1080p
low377 FPS393 FPS
medium303 FPS314 FPS
high249 FPS262 FPS
ultra190 FPS197 FPS
1440p
low265 FPS295 FPS
medium228 FPS236 FPS
high186 FPS197 FPS
ultra142 FPS147 FPS
4K
low155 FPS197 FPS
medium143 FPS157 FPS
high102 FPS131 FPS
ultra70 FPS98 FPS
Valorant

Valorant

PresetRadeon PRO W6400Radeon R9 295X2
1080p
low285 FPS240 FPS
medium206 FPS207 FPS
high180 FPS168 FPS
ultra146 FPS143 FPS
1440p
low210 FPS179 FPS
medium149 FPS155 FPS
high132 FPS120 FPS
ultra104 FPS98 FPS
4K
low105 FPS103 FPS
medium76 FPS82 FPS
high67 FPS65 FPS
ultra51 FPS50 FPS

Technical Specifications

Side-by-side comparison of Radeon PRO W6400 and Radeon R9 295X2

AMD

Radeon PRO W6400

The Radeon PRO W6400 is manufactured by AMD. It was released in January 19 2022. It features the RDNA 2.0 architecture. The core clock ranges from 2331 MHz to 2331 MHz. It has 768 shading units. The thermal design power (TDP) is 50W. Manufactured using 6 nm process technology. It features 12 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 8,428 points.

AMD

Radeon R9 295X2

The Radeon R9 295X2 is manufactured by AMD. It was released in April 29 2014. It features the GCN 2.0 architecture. The boost clock speed is 1018 MHz. It has 2816 ×2 shading units. The thermal design power (TDP) is 500W. Manufactured using 28 nm process technology. G3D Mark benchmark score: 8,734 points. Launch price was $1,499.

Graphics Performance

The Radeon PRO W6400 scores 8,428 and the Radeon R9 295X2 reaches 8,734 in the G3D Mark benchmark — just a 3.6% difference, making them near-identical in rasterization performance. The Radeon PRO W6400 is built on RDNA 2.0 while the Radeon R9 295X2 uses GCN 2.0, both on 6 nm vs 28 nm. Shader units: 768 (Radeon PRO W6400) vs 2,816 (Radeon R9 295X2). Raw compute: 3.58 TFLOPS (Radeon PRO W6400) vs 5.733 TFLOPS ×2 (Radeon R9 295X2). Boost clocks: 2331 MHz vs 1018 MHz.

FeatureRadeon PRO W6400Radeon R9 295X2
G3D Mark Score
8,428
8,734+4%
Architecture
RDNA 2.0
GCN 2.0
Process Node
6 nm
28 nm
Shading Units
768
2816 ×2+267%
Compute (TFLOPS)
3.58 TFLOPS
5.733 TFLOPS ×2+60%
Boost Clock
2331 MHz+129%
1018 MHz
ROPs
32
64 ×2+100%
TMUs
48
176 ×2+267%
L1 Cache
256 KB
704 KB+175%
L2 Cache
1 MB
1 MB
Frame Generation
FSR upscaling + RSR
FSR upscaling

Advanced Features (DLSS/FSR)

FeatureRadeon PRO W6400Radeon R9 295X2
Upscaling Tech
FSR Upscaling / FSR 4
FSR Upscaling / FSR 4
Frame Generation
Not Supported
Not Supported
Ray Reconstruction
No
No
Low Latency
AMD Anti-Lag
AMD Anti-Lag
💾

Video Memory (VRAM)

The Radeon PRO W6400 comes with 4 GB of VRAM, while the Radeon R9 295X2 has 8 GB. The Radeon R9 295X2 offers 100% more capacity, crucial for higher resolutions and texture-heavy games. Bus width: 256-bit vs 512-bit x2.

FeatureRadeon PRO W6400Radeon R9 295X2
VRAM Capacity
4 GB
8 GB+100%
Memory Type
GDDR6
GDDR5
Bus Width
256-bit
512-bit x2+100%
L2 Cache
1 MB
1 MB
🖥️

Display & API Support

DirectX support: 12.2 (Radeon PRO W6400) vs 12.0 (Radeon R9 295X2). Vulkan: 1.2 vs 1.1. OpenGL: 4.6 vs 4.3. Maximum simultaneous displays: 2 vs 6.

FeatureRadeon PRO W6400Radeon R9 295X2
DirectX
12.2+2%
12.0
Vulkan
1.2+9%
1.1
OpenGL
4.6+7%
4.3
Max Displays
2
6+200%
🎬

Media & Encoding

Hardware encoder: VCN 3.0 (Radeon PRO W6400) vs VCE 2.0 (Radeon R9 295X2). Decoder: VCN 3.0 vs UVD 4.2. Supported codecs: MPEG-2,H.264,HEVC,VP9,AV1 (Decode) (Radeon PRO W6400) vs MPEG-2,H.264,VC-1 (Radeon R9 295X2).

FeatureRadeon PRO W6400Radeon R9 295X2
Encoder
VCN 3.0
VCE 2.0
Decoder
VCN 3.0
UVD 4.2
Codecs
MPEG-2,H.264,HEVC,VP9,AV1 (Decode)
MPEG-2,H.264,VC-1
🔌

Power & Dimensions

The Radeon PRO W6400 draws 50W versus the Radeon R9 295X2's 500W — a 163.6% difference. The Radeon PRO W6400 is more power-efficient. Recommended PSU: 500W (Radeon PRO W6400) vs 1000W (Radeon R9 295X2). Power connectors: PCIe-powered vs 2x 8-pin. Card length: 168mm vs 307mm, occupying 1 vs 2 slots. Typical load temperature: 70°C vs 65°C.

FeatureRadeon PRO W6400Radeon R9 295X2
TDP
50W-90%
500W
Recommended PSU
500W-50%
1000W
Power Connector
PCIe-powered
2x 8-pin
Length
168mm
307mm
Height
69mm
114mm
Slots
1-50%
2
Temp (Load)
70°C
65°C-7%
Perf/Watt
168.6+863%
17.5
💰

Value Analysis

The Radeon PRO W6400 launched at $229 MSRP, while the Radeon R9 295X2 launched at $1499. The Radeon PRO W6400 costs 84.7% less ($1270 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 36.8 (Radeon PRO W6400) vs 5.8 (Radeon R9 295X2) — the Radeon PRO W6400 offers 534.5% better value. The Radeon PRO W6400 is the newer GPU (2022 vs 2014).

FeatureRadeon PRO W6400Radeon R9 295X2
MSRP
$229-85%
$1499
Performance per Dollar
36.8+534%
5.8
Codename
Navi 24
Vesuvius
Release
January 19 2022
April 29 2014
Ranking
#308
#303