EPYC 75F3 vs EPYC 4564P

AMD

EPYC 75F3

32 Cores64 Thrd280 WWMax: 4 GHz2021

Popular choices:

VS
AMD

EPYC 4564P

16 Cores32 Thrd170 WWMax: 5.7 GHz2024

Popular choices:

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

EPYC 75F3

2021

Why buy it

  • +0.2% higher PassMark.
  • +300% larger total L3 cache (256 MB vs 64 MB).
  • 357.1% more PCIe lanes (128 vs 28) for storage and expansion-heavy builds.

Trade-offs

  • Worse for gaming: lower average FPS than EPYC 4564P across 4 shared CPU benchmark tests.
  • Lower PassMark per dollar, at 12.0 vs 42.4 PassMark/$ ($5,383 MSRP vs $1,517 MSRP).
  • 64.7% higher power demand at 280W vs 170W.
  • Older platform position on SP3 with DDR4, while EPYC 4564P moves to AM5 and DDR5.
  • No integrated graphics, while EPYC 4564P can still boot and troubleshoot without a discrete GPU.

EPYC 4564P

2024

Why buy it

  • Better for gaming: +33.9% higher average FPS across 4 shared CPU benchmark tests.
  • Costs $3,866 less on MSRP ($1,517 MSRP vs $5,383 MSRP).
  • Delivers 254.2% more PassMark for each dollar spent, at 42.4 vs 12.0 PassMark/$ ($1,517 MSRP vs $5,383 MSRP).
  • Draws 170W instead of 280W, a 110W reduction.
  • Newer platform on AM5 with DDR5 support instead of SP3 and DDR4.

Trade-offs

  • Lower PassMark (64,387 vs 64,505).
  • Smaller total L3 cache (64 MB vs 256 MB).

Quick Answers

So, is EPYC 4564P better than EPYC 75F3?
It depends on what matters more to you. For gaming, EPYC 4564P is ahead with a 33.9% average FPS lead across 4 shared CPU game tests in our data. For rendering, compiling, streaming, and heavier multitasking, EPYC 75F3 pulls ahead with 0.2% better PassMark. EPYC 75F3 also has the bigger cache pool with 300% larger total L3 cache (256 MB vs 64 MB).
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, EPYC 75F3 is the better fit. You are getting 0.2% better PassMark, backed by 32 cores and 64 threads. It also carries the larger cache pool with 300% larger total L3 cache (256 MB vs 64 MB).
Which one is the smarter buy today, not just the cheaper CPU?
EPYC 4564P is the smarter buy today. EPYC 4564P is $3,866 cheaper on MSRP at $1,517 MSRP versus $5,383 MSRP, and it gives you a 33.9% average FPS lead across 4 shared CPU game tests in our data. The trade-off is that EPYC 75F3 is still stronger for heavier multi-core work with 0.2% better PassMark. It is also 254.2% better value on MSRP (42.4 vs 12.0 PassMark/$), so the better CPU is not just faster, it is also the cleaner value play on paper.
Which one is more future-proof for 2026 and beyond?
EPYC 4564P is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2024 vs 2021), a healthier platform with AM5 and DDR5 instead of SP3, and AVX-512 support for heavier modern compute workloads. That should give you a better long-term upgrade path for motherboard, RAM, and future CPU swaps.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Path of Exile 2

Path of Exile 2

PresetEPYC 75F3EPYC 4564P
1080p
low198 FPS289 FPS
medium161 FPS262 FPS
high130 FPS216 FPS
ultra100 FPS183 FPS
1440p
low162 FPS271 FPS
medium126 FPS223 FPS
high98 FPS173 FPS
ultra78 FPS153 FPS
4K
low73 FPS186 FPS
medium61 FPS153 FPS
high47 FPS118 FPS
ultra39 FPS104 FPS
Counter-Strike 2

Counter-Strike 2

PresetEPYC 75F3EPYC 4564P
1080p
low507 FPS765 FPS
medium443 FPS631 FPS
high354 FPS468 FPS
ultra288 FPS396 FPS
1440p
low417 FPS628 FPS
medium373 FPS537 FPS
high308 FPS412 FPS
ultra243 FPS322 FPS
4K
low257 FPS353 FPS
medium234 FPS305 FPS
high205 FPS267 FPS
ultra171 FPS225 FPS
League of Legends

League of Legends

PresetEPYC 75F3EPYC 4564P
1080p
low948 FPS1025 FPS
medium792 FPS1139 FPS
high734 FPS1058 FPS
ultra657 FPS875 FPS
1440p
low661 FPS971 FPS
medium552 FPS858 FPS
high503 FPS772 FPS
ultra442 FPS656 FPS
4K
low472 FPS596 FPS
medium374 FPS518 FPS
high330 FPS465 FPS
ultra268 FPS393 FPS
Valorant

Valorant

PresetEPYC 75F3EPYC 4564P
1080p
low1006 FPS1294 FPS
medium908 FPS1015 FPS
high782 FPS982 FPS
ultra679 FPS855 FPS
1440p
low770 FPS1021 FPS
medium671 FPS890 FPS
high575 FPS764 FPS
ultra500 FPS640 FPS
4K
low556 FPS756 FPS
medium495 FPS659 FPS
high435 FPS571 FPS
ultra374 FPS437 FPS

Technical Specifications

Side-by-side comparison of EPYC 75F3 and EPYC 4564P

AMD

EPYC 75F3

The EPYC 75F3 is manufactured by AMD. It was released in 15 March 2021 (4 years ago). It is based on the Milan (2021−2023) architecture. It features 32 cores and 64 threads. Base frequency is 2.95 GHz, with boost up to 4 GHz. L3 cache: 256 MB (total). L2 cache: 512 kB (per core). Built on 7 nm+ process technology. Socket: SP3. Thermal design power (TDP): 280 Watt. Memory support: DDR4-3200. Passmark benchmark score: 64,505 points. Launch price was $4,860.

AMD

EPYC 4564P

The EPYC 4564P is manufactured by AMD. It was released in 21 May 2024 (1 year ago). It is based on the Raphael (2023−2025) architecture. It features 16 cores and 32 threads. Base frequency is 4.5 GHz, with boost up to 5.7 GHz. L3 cache: 64 MB (total). L2 cache: 1 MB (per core). Built on 5 nm process technology. Socket: AM5. Thermal design power (TDP): 170 Watt. Memory support: DDR5. Passmark benchmark score: 64,387 points. Launch price was $699.

Processing Power

The EPYC 75F3 packs 32 cores / 64 threads, while the EPYC 4564P offers 16 cores / 32 threads — the EPYC 75F3 has 16 more cores. Boost clocks reach 4 GHz on the EPYC 75F3 versus 5.7 GHz on the EPYC 4564P — a 35.1% clock advantage for the EPYC 4564P (base: 2.95 GHz vs 4.5 GHz). The EPYC 75F3 uses the Milan (2021−2023) architecture (7 nm+), while the EPYC 4564P uses Raphael (2023−2025) (5 nm). In PassMark, the EPYC 75F3 scores 64,505 against the EPYC 4564P's 64,387 — a 0.2% lead for the EPYC 75F3. L3 cache: 256 MB (total) on the EPYC 75F3 vs 64 MB (total) on the EPYC 4564P.

FeatureEPYC 75F3EPYC 4564P
Cores / Threads
32 / 64+100%
16 / 32
Boost Clock
4 GHz
5.7 GHz+43%
Base Clock
2.95 GHz
4.5 GHz+53%
L3 Cache
256 MB (total)+300%
64 MB (total)
L2 Cache
512 kB (per core)
1 MB (per core)+100%
Process
7 nm+
5 nm-29%
Architecture
Milan (2021−2023)
Raphael (2023−2025)
PassMark
64,505
64,387
Cinebench R23 Multi
38,500
Geekbench 6 Single
2,975
Geekbench 6 Multi
18,581
🧠

Memory & Platform

The EPYC 75F3 uses the SP3 socket (PCIe 4.0), while the EPYC 4564P uses AM5 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 3200 on the EPYC 75F3 versus DDR5-5200 on the EPYC 4564P — the EPYC 75F3 supports 199.4% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 75F3 supports up to 4096 of RAM compared to 192 GB 182.1% more capacity for professional workloads. Memory channels: 8 (EPYC 75F3) vs 2 (EPYC 4564P). PCIe lanes: 128 (EPYC 75F3) vs 28 (EPYC 4564P) — the EPYC 75F3 offers 100 more lanes for additional GPUs or NVMe drives. Chipset compatibility: SP3 (EPYC 75F3) and X670E,X670,B650E,B650 (EPYC 4564P).

FeatureEPYC 75F3EPYC 4564P
Socket
SP3
AM5
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
3200+63900%
DDR5-5200
Max RAM Capacity
4096
192 GB+4915100%
RAM Channels
8+300%
2
ECC Support
Yes
Yes
PCIe Lanes
128+357%
28
🔧

Advanced Features

Neither processor supports overclocking. Only the EPYC 4564P supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: VT-x, VT-d (EPYC 75F3) vs AMD-V, AMD-Vi (EPYC 4564P). The EPYC 4564P includes integrated graphics (Radeon Graphics), while the EPYC 75F3 requires a dedicated GPU. Primary use case: EPYC 4564P targets High-end Server / Workstation. Direct competitor: EPYC 75F3 rivals Xeon Platinum 8380; EPYC 4564P rivals Ryzen 9 7950X.

FeatureEPYC 75F3EPYC 4564P
Integrated GPU
No
Yes
IGPU Model
None
Radeon Graphics
Unlocked
No
No
AVX-512
No
Yes
Virtualization
VT-x, VT-d
AMD-V, AMD-Vi
Target Use
High-end Server / Workstation
💰

Value Analysis

The EPYC 75F3 launched at $5383 MSRP, while the EPYC 4564P debuted at $1517. On MSRP ($5383 vs $1517), the EPYC 4564P is $3866 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 75F3 delivers 12.0 pts/$ vs 42.4 pts/$ for the EPYC 4564P — making the EPYC 4564P the 111.9% better value option.

FeatureEPYC 75F3EPYC 4564P
MSRP
$5383
$1517-72%
Performance per Dollar
12.0
42.4+253%
Release Date
2021
2024