EPYC 4545P vs Xeon Platinum 8160M

CPU

GPU

EPYC 4545P

16 Cores32 Thrd65 WWMax: 5.4 GHz2025

Popular choices:

•••••••••

Xeon Platinum 8160M

24 Cores48 Thrd150 WWMax: 3.7 GHz2017

Popular choices:

•••••••••

Performance Spectrum - CPU

EPYC 4545P

16 / 32

54,255

+2.1%

Ryzen Threadripper PRO 7965WX

Ryzen Threadripper PRO 5995WX

Ryzen Threadripper 9970X

Xeon Platinum 8160M

24 / 48

53,158

0.0%

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

EPYC 4545P

2025

Why buy it

✅Better for gaming: +57.6% higher average FPS across 2 shared CPU benchmark tests.
✅+93.9% larger total L3 cache (64 MB vs 33 MB).
✅Costs $4,451 less on MSRP ($549 MSRP vs $5,000 MSRP).
✅Delivers 829.5% more PassMark for each dollar spent, at 98.8 vs 10.6 PassMark/$ ($549 MSRP vs $5,000 MSRP).
✅Draws 65W instead of 150W, a 85W reduction.

Trade-offs

❌Fewer obvious downsides in this matchup outside of normal market pricing swings.

Xeon Platinum 8160M

2017

Why buy it

✅71.4% more PCIe lanes (48 vs 28) for storage and expansion-heavy builds.

Trade-offs

❌Worse for gaming: lower average FPS than EPYC 4545P across 2 shared CPU benchmark tests.
❌Lower PassMark (53,158 vs 54,255).
❌Smaller total L3 cache (33 MB vs 64 MB).
❌Lower PassMark per dollar, at 10.6 vs 98.8 PassMark/$ ($5,000 MSRP vs $549 MSRP).
❌130.8% higher power demand at 150W vs 65W.

EPYC 4545P

2025

Xeon Platinum 8160M

2017

Why buy it

✅Better for gaming: +57.6% higher average FPS across 2 shared CPU benchmark tests.
✅+93.9% larger total L3 cache (64 MB vs 33 MB).
✅Costs $4,451 less on MSRP ($549 MSRP vs $5,000 MSRP).
✅Delivers 829.5% more PassMark for each dollar spent, at 98.8 vs 10.6 PassMark/$ ($549 MSRP vs $5,000 MSRP).
✅Draws 65W instead of 150W, a 85W reduction.

Why buy it

✅71.4% more PCIe lanes (48 vs 28) for storage and expansion-heavy builds.

Trade-offs

❌Fewer obvious downsides in this matchup outside of normal market pricing swings.

Trade-offs

❌Worse for gaming: lower average FPS than EPYC 4545P across 2 shared CPU benchmark tests.
❌Lower PassMark (53,158 vs 54,255).
❌Smaller total L3 cache (33 MB vs 64 MB).
❌Lower PassMark per dollar, at 10.6 vs 98.8 PassMark/$ ($5,000 MSRP vs $549 MSRP).
❌130.8% higher power demand at 150W vs 65W.

Quick Answers

So, is EPYC 4545P better than Xeon Platinum 8160M?

Yes. EPYC 4545P is the better overall CPU here. You are getting a 57.6% average FPS lead across 2 shared CPU game tests in our data, 2.1% better PassMark, and the stronger long-term platform, which makes it the stronger all-around choice.

Which one is better for gaming?

If gaming is the priority, EPYC 4545P is the better pick here. According to our tests, it delivers 57.6% more average FPS across 2 shared CPU game tests.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, EPYC 4545P is the better fit. You are getting 2.1% better PassMark, backed by 16 cores and 32 threads. It also carries the larger cache pool with 93.9% larger total L3 cache (64 MB vs 33 MB).

Which one is the smarter buy today, not just the cheaper CPU?

EPYC 4545P is the smarter buy today. EPYC 4545P is $4,451 cheaper on MSRP at $549 MSRP versus $5,000 MSRP, and it gives you a 57.6% average FPS lead across 2 shared CPU game tests in our data. It is also 829.5% better value on MSRP (98.8 vs 10.6 PassMark/$), so the better CPU is not just faster, it is also the cleaner value play on paper.

Which one is more future-proof for 2026 and beyond?

EPYC 4545P is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2025 vs 2017), a healthier platform with AM5 and DDR5 instead of LGA3647, 93.9% larger total L3 cache (64 MB vs 33 MB), and more multi-core headroom with 16 cores / 32 threads instead of 24/48. That should give you a better long-term upgrade path for motherboard, RAM, and future CPU swaps.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

EPYC 4545P Benchmark Check

Xeon Platinum 8160M Benchmark Check

Path of Exile 2

Preset	EPYC 4545P	Xeon Platinum 8160M
1080p
low	286 FPS	195 FPS
medium	262 FPS	158 FPS
high	215 FPS	128 FPS
ultra	181 FPS	100 FPS
1440p
low	262 FPS	157 FPS
medium	218 FPS	123 FPS
high	167 FPS	96 FPS
ultra	148 FPS	76 FPS
4K
low	182 FPS	72 FPS
medium	151 FPS	60 FPS
high	115 FPS	47 FPS
ultra	102 FPS	38 FPS

Open EPYC 4545P Open Xeon Platinum 8160M

Path of Exile 2

Path of Exile 2

Counter-Strike 2

Preset	EPYC 4545P	Xeon Platinum 8160M
1080p
low	674 FPS	212 FPS
medium	580 FPS	188 FPS
high	434 FPS	161 FPS
ultra	375 FPS	137 FPS
1440p
low	567 FPS	184 FPS
medium	506 FPS	167 FPS
high	392 FPS	143 FPS
ultra	312 FPS	120 FPS
4K
low	320 FPS	120 FPS
medium	289 FPS	109 FPS
high	255 FPS	100 FPS
ultra	219 FPS	82 FPS

Open EPYC 4545P Open Xeon Platinum 8160M

Counter-Strike 2

Counter-Strike 2

League of Legends

Preset	EPYC 4545P	Xeon Platinum 8160M
1080p
low	850 FPS	894 FPS
medium	679 FPS	779 FPS
high	601 FPS	736 FPS
ultra	515 FPS	652 FPS
1440p
low	679 FPS	710 FPS
medium	543 FPS	610 FPS
high	469 FPS	576 FPS
ultra	398 FPS	508 FPS
4K
low	484 FPS	458 FPS
medium	401 FPS	360 FPS
high	360 FPS	320 FPS
ultra	302 FPS	260 FPS

Open EPYC 4545P Open Xeon Platinum 8160M

League of Legends

League of Legends

Valorant

Preset	EPYC 4545P	Xeon Platinum 8160M
1080p
low	1072 FPS	848 FPS
medium	966 FPS	767 FPS
high	843 FPS	670 FPS
ultra	760 FPS	583 FPS
1440p
low	842 FPS	679 FPS
medium	747 FPS	593 FPS
high	652 FPS	515 FPS
ultra	566 FPS	442 FPS
4K
low	619 FPS	477 FPS
medium	553 FPS	427 FPS
high	487 FPS	381 FPS
ultra	421 FPS	330 FPS

Open EPYC 4545P Open Xeon Platinum 8160M

Valorant

Valorant

Check FPS for your specific build

Technical Specifications

Side-by-side comparison of EPYC 4545P and Xeon Platinum 8160M

EPYC 4545P

The EPYC 4545P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 16 cores and 32 threads. Base frequency is 3 GHz, with boost up to 5.4 GHz. L3 cache: 64 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 65 Watt. Memory support: DDR5. Passmark benchmark score: 54,255 points. Launch price was $549.

Xeon Platinum 8160M

The Xeon Platinum 8160M is manufactured by Intel. It was released in 25 April 2017 (8 years ago). It is based on the Skylake (server) (2017−2018) architecture. It features 24 cores and 48 threads. Base frequency is 2.1 GHz, with boost up to 3.7 GHz. L3 cache: 33 MB. L2 cache: 24 MB. Built on 14 nm process technology. Socket: LGA3647. Thermal design power (TDP): 150 Watt. Memory support: DDR4-2666. Passmark benchmark score: 53,158 points. Launch price was $7,704.

⚡

Processing Power

The EPYC 4545P packs 16 cores / 32 threads, while the Xeon Platinum 8160M offers 24 cores / 48 threads — the Xeon Platinum 8160M has 8 more cores. Boost clocks reach 5.4 GHz on the EPYC 4545P versus 3.7 GHz on the Xeon Platinum 8160M — a 37.4% clock advantage for the EPYC 4545P (base: 3 GHz vs 2.1 GHz). The EPYC 4545P uses the Grado (2025) architecture (4 nm), while the Xeon Platinum 8160M uses Skylake (server) (2017−2018) (14 nm). In PassMark, the EPYC 4545P scores 54,255 against the Xeon Platinum 8160M's 53,158 — a 2% lead for the EPYC 4545P. L3 cache: 64 MB (total) on the EPYC 4545P vs 33 MB on the Xeon Platinum 8160M.

Feature	EPYC 4545P	Xeon Platinum 8160M
Cores / Threads	16 / 32	24 / 48+50%
Boost Clock	5.4 GHz+46%	3.7 GHz
Base Clock	3 GHz+43%	2.1 GHz
L3 Cache	64 MB (total)+94%	33 MB
L2 Cache	1 MB (per core)	24 MB+2300%
Process	4 nm-71%	14 nm
Architecture	Grado (2025)	Skylake (server) (2017−2018)
PassMark	54,255+2%	53,158
Geekbench 6 Single	—	850
Geekbench 6 Multi	—	15,000

🧠

Memory & Platform

The EPYC 4545P uses the AM5 socket (PCIe 4.0), while the Xeon Platinum 8160M uses LGA3647 (PCIe 3.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 5600 on the EPYC 4545P versus DDR4-2666 on the Xeon Platinum 8160M — the EPYC 4545P supports 199.7% faster memory, which can translate to measurable gains in memory-sensitive workloads. The Xeon Platinum 8160M supports up to 1536 GB of RAM compared to 192 — 155.6% more capacity for professional workloads. Memory channels: 2 (EPYC 4545P) vs 6 (Xeon Platinum 8160M). PCIe lanes: 28 (EPYC 4545P) vs 48 (Xeon Platinum 8160M) — the Xeon Platinum 8160M offers 20 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AM5 (EPYC 4545P) and C621 (Xeon Platinum 8160M).

Feature	EPYC 4545P	Xeon Platinum 8160M
Socket	AM5	LGA3647
PCIe Generation	PCIe 4.0+33%	PCIe 3.0
Max RAM Speed	5600+139900%	DDR4-2666
Max RAM Capacity	192	1536 GB+838860700%
RAM Channels	2	6+200%
ECC Support	Yes	Yes
PCIe Lanes	28	48+71%

🔧

Advanced Features

Only the EPYC 4545P has an unlocked multiplier for overclocking — a significant advantage for enthusiasts seeking extra performance. Both support AVX-512 instructions, benefiting scientific computing, AI inference, and encryption workloads. Virtualization support: VT-x, VT-d, AMD-V (EPYC 4545P) vs VT-x, VT-d (Xeon Platinum 8160M). The EPYC 4545P includes integrated graphics (AMD Radeon Graphics), while the Xeon Platinum 8160M requires a dedicated GPU. Primary use case: Xeon Platinum 8160M targets Datacenter. Direct competitor: EPYC 4545P rivals Ryzen 9 7900X; Xeon Platinum 8160M rivals EPYC 7401.

Feature	EPYC 4545P	Xeon Platinum 8160M
Integrated GPU	Yes	No
IGPU Model	AMD Radeon Graphics	None
Unlocked	Yes	No
AVX-512	Yes	Yes
Virtualization	VT-x, VT-d, AMD-V	VT-x, VT-d
Target Use	—	Datacenter

💰

Value Analysis

The EPYC 4545P launched at $549 MSRP, while the Xeon Platinum 8160M debuted at $5000. On MSRP ($549 vs $5000), the EPYC 4545P is $4451 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 4545P delivers 98.8 pts/$ vs 10.6 pts/$ for the Xeon Platinum 8160M — making the EPYC 4545P the 161.1% better value option.