EPYC 4545P vs EPYC 7401

AMD

EPYC 4545P

16 Cores32 Thrd65 WWMax: 5.4 GHz2025

Popular choices:

VS
AMD

EPYC 7401

24 Cores48 Thrd155 WWMax: 3 GHz2017

Popular choices:

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

EPYC 4545P

2025

Why buy it

  • Better for gaming: +64.0% higher average FPS across 2 shared CPU benchmark tests.
  • Costs $951 less on MSRP ($549 MSRP vs $1,500 MSRP).
  • Delivers 168.2% more PassMark for each dollar spent, at 98.8 vs 36.9 PassMark/$ ($549 MSRP vs $1,500 MSRP).
  • Draws 65W instead of 155W, a 90W reduction.
  • Newer platform on AM5 with DDR5 support instead of TR4 and DDR4.

Trade-offs

  • Lower PassMark (54,255 vs 55,280).

EPYC 7401

2017

Why buy it

  • +1.9% higher PassMark.
  • 357.1% more PCIe lanes (128 vs 28) for storage and expansion-heavy builds.

Trade-offs

  • Worse for gaming: lower average FPS than EPYC 4545P across 2 shared CPU benchmark tests.
  • Lower PassMark per dollar, at 36.9 vs 98.8 PassMark/$ ($1,500 MSRP vs $549 MSRP).
  • 138.5% higher power demand at 155W vs 65W.
  • Older platform position on TR4 with DDR4, while EPYC 4545P moves to AM5 and DDR5.
  • No integrated graphics, while EPYC 4545P can still boot and troubleshoot without a discrete GPU.

Quick Answers

So, is EPYC 4545P better than EPYC 7401?
It depends on what matters more to you. For gaming, EPYC 4545P is ahead with a 64.0% average FPS lead across 2 shared CPU game tests in our data. For rendering, compiling, streaming, and heavier multitasking, EPYC 7401 pulls ahead with 1.9% better PassMark.
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, EPYC 7401 is the better fit. You are getting 1.9% better PassMark, backed by 24 cores and 48 threads.
Which one is the smarter buy today, not just the cheaper CPU?
EPYC 4545P is the smarter buy today. EPYC 4545P is $951 cheaper on MSRP at $549 MSRP versus $1,500 MSRP, and it gives you a 64.0% average FPS lead across 2 shared CPU game tests in our data. The trade-off is that EPYC 7401 is still stronger for heavier multi-core work with 1.9% better PassMark. It is also 168.2% better value on MSRP (98.8 vs 36.9 PassMark/$), so the better CPU is not just faster, it is also the cleaner value play on paper.
Which one is more future-proof for 2026 and beyond?
EPYC 4545P is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2025 vs 2017), a healthier platform with AM5 and DDR5 instead of TR4, and AVX-512 support for heavier modern compute workloads. That should give you a better long-term upgrade path for motherboard, RAM, and future CPU swaps.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Path of Exile 2

Path of Exile 2

PresetEPYC 4545PEPYC 7401
1080p
low286 FPS187 FPS
medium262 FPS165 FPS
high215 FPS132 FPS
ultra181 FPS105 FPS
1440p
low262 FPS153 FPS
medium218 FPS127 FPS
high167 FPS97 FPS
ultra148 FPS78 FPS
4K
low182 FPS71 FPS
medium151 FPS63 FPS
high115 FPS48 FPS
ultra102 FPS39 FPS
Counter-Strike 2

Counter-Strike 2

PresetEPYC 4545PEPYC 7401
1080p
low674 FPS207 FPS
medium580 FPS188 FPS
high434 FPS160 FPS
ultra375 FPS131 FPS
1440p
low567 FPS178 FPS
medium506 FPS163 FPS
high392 FPS141 FPS
ultra312 FPS111 FPS
4K
low320 FPS112 FPS
medium289 FPS103 FPS
high255 FPS92 FPS
ultra219 FPS75 FPS
League of Legends

League of Legends

PresetEPYC 4545PEPYC 7401
1080p
low850 FPS620 FPS
medium679 FPS518 FPS
high601 FPS466 FPS
ultra515 FPS399 FPS
1440p
low679 FPS517 FPS
medium543 FPS432 FPS
high469 FPS378 FPS
ultra398 FPS325 FPS
4K
low484 FPS383 FPS
medium401 FPS308 FPS
high360 FPS270 FPS
ultra302 FPS220 FPS
Valorant

Valorant

PresetEPYC 4545PEPYC 7401
1080p
low1072 FPS834 FPS
medium966 FPS758 FPS
high843 FPS651 FPS
ultra760 FPS561 FPS
1440p
low842 FPS667 FPS
medium747 FPS584 FPS
high652 FPS500 FPS
ultra566 FPS420 FPS
4K
low619 FPS475 FPS
medium553 FPS427 FPS
high487 FPS375 FPS
ultra421 FPS320 FPS

Technical Specifications

Side-by-side comparison of EPYC 4545P and EPYC 7401

AMD

EPYC 4545P

The EPYC 4545P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 16 cores and 32 threads. Base frequency is 3 GHz, with boost up to 5.4 GHz. L3 cache: 64 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 65 Watt. Memory support: DDR5. Passmark benchmark score: 54,255 points. Launch price was $549.

AMD

EPYC 7401

The EPYC 7401 is manufactured by AMD. It was released in 29 June 2017 (8 years ago). It is based on the Naples (2017−2018) architecture. It features 24 cores and 48 threads. Base frequency is 2 GHz, with boost up to 3 GHz. L3 cache: 64 MB (total). L2 cache: 512K (per core). Built on 14 nm process technology. Socket: TR4. Thermal design power (TDP): 170 Watt. Memory support: DDR4 Eight-channel. Passmark benchmark score: 55,280 points. Launch price was $1,850.

Processing Power

The EPYC 4545P packs 16 cores / 32 threads, while the EPYC 7401 offers 24 cores / 48 threads — the EPYC 7401 has 8 more cores. Boost clocks reach 5.4 GHz on the EPYC 4545P versus 3 GHz on the EPYC 7401 — a 57.1% clock advantage for the EPYC 4545P (base: 3 GHz vs 2 GHz). The EPYC 4545P uses the Grado (2025) architecture (4 nm), while the EPYC 7401 uses Naples (2017−2018) (14 nm). In PassMark, the EPYC 4545P scores 54,255 against the EPYC 7401's 55,280 — a 1.9% lead for the EPYC 7401. Both processors carry 64 MB (total) of L3 cache.

FeatureEPYC 4545PEPYC 7401
Cores / Threads
16 / 32
24 / 48+50%
Boost Clock
5.4 GHz+80%
3 GHz
Base Clock
3 GHz+50%
2 GHz
L3 Cache
64 MB (total)
64 MB (total)
L2 Cache
1 MB (per core)+100%
512K (per core)
Process
4 nm-71%
14 nm
Architecture
Grado (2025)
Naples (2017−2018)
PassMark
54,255
55,280+2%
🧠

Memory & Platform

The EPYC 4545P uses the AM5 socket (PCIe 4.0), while the EPYC 7401 uses TR4 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 5600 on the EPYC 4545P versus 2666 on the EPYC 7401 — the EPYC 4545P supports 71% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7401 supports up to 2048 of RAM compared to 192 165.7% more capacity for professional workloads. Memory channels: 2 (EPYC 4545P) vs 8 (EPYC 7401). PCIe lanes: 28 (EPYC 4545P) vs 128 (EPYC 7401) — the EPYC 7401 offers 100 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AM5 (EPYC 4545P) and SP3 (EPYC 7401).

FeatureEPYC 4545PEPYC 7401
Socket
AM5
TR4
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
5600+110%
2666
Max RAM Capacity
192
2048+967%
RAM Channels
2
8+300%
ECC Support
Yes
Yes
PCIe Lanes
28
128+357%
🔧

Advanced Features

Only the EPYC 4545P has an unlocked multiplier for overclocking — a significant advantage for enthusiasts seeking extra performance. Only the EPYC 4545P supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: VT-x, VT-d, AMD-V (EPYC 4545P) vs VT-x, VT-d (EPYC 7401). The EPYC 4545P includes integrated graphics (AMD Radeon Graphics), while the EPYC 7401 requires a dedicated GPU. Direct competitor: EPYC 4545P rivals Ryzen 9 7900X; EPYC 7401 rivals Xeon Silver 4114.

FeatureEPYC 4545PEPYC 7401
Integrated GPU
Yes
No
IGPU Model
AMD Radeon Graphics
None
Unlocked
Yes
No
AVX-512
Yes
No
Virtualization
VT-x, VT-d, AMD-V
VT-x, VT-d
💰

Value Analysis

The EPYC 4545P launched at $549 MSRP, while the EPYC 7401 debuted at $1500. On MSRP ($549 vs $1500), the EPYC 4545P is $951 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 4545P delivers 98.8 pts/$ vs 36.9 pts/$ for the EPYC 7401 — making the EPYC 4545P the 91.4% better value option.

FeatureEPYC 4545PEPYC 7401
MSRP
$549-63%
$1500
Performance per Dollar
98.8+168%
36.9
Release Date
2025
2017