EPYC 4545P vs Ryzen 9 5900X

AMD

EPYC 4545P

16 Cores32 Thrd65 WWMax: 5.4 GHz2025

Popular choices:

VS
AMD

Ryzen 9 5900X

12 Cores24 Thrd105 WWMax: 4.8 GHz2020

Popular choices:

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

EPYC 4545P

2025

Why buy it

  • +39.3% higher PassMark.
  • Better for workstations and heavier parallel workloads: 16 cores / 32 threads, plus 28 PCIe lanes vs 24.
  • Delivers 39.3% more PassMark for each dollar spent, at 98.8 vs 71.0 PassMark/$ ($549 MSRP vs $549 MSRP).
  • Draws 65W instead of 105W, a 40W reduction.
  • Newer platform on AM5 with DDR5 support instead of AM4 and DDR4.

Trade-offs

  • Worse for gaming: lower average FPS than Ryzen 9 5900X across 4 shared CPU benchmark tests.

Ryzen 9 5900X

2020

Why buy it

  • Better for gaming: +5.3% higher average FPS across 4 shared CPU benchmark tests.

Trade-offs

  • Lower PassMark (38,955 vs 54,255).
  • Less compelling for workstation-style loads than EPYC 4545P, which brings 16 cores / 32 threads and 28 PCIe lanes.
  • Lower PassMark per dollar, at 71.0 vs 98.8 PassMark/$ ($549 MSRP vs $549 MSRP).
  • 61.5% higher power demand at 105W vs 65W.
  • Older platform position on AM4 with DDR4, while EPYC 4545P moves to AM5 and DDR5.

Quick Answers

So, is EPYC 4545P better than Ryzen 9 5900X?
Not in a simple one-size-fits-all way. EPYC 4545P makes more sense for workstation-style multi-core throughput, while Ryzen 9 5900X is the better mainstream desktop choice for gaming, platform cost, and day-to-day practicality.
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, EPYC 4545P is the better fit. You are getting 39.3% better PassMark, backed by 16 cores and 32 threads.
Which one is the smarter buy today, not just the cheaper CPU?
EPYC 4545P is the smarter buy today. EPYC 4545P is in basically the same MSRP band at $549 MSRP versus $549 MSRP, and it gives you 39.3% better PassMark. The trade-off is that Ryzen 9 5900X is still the better pure gaming CPU with a 5.3% average FPS lead across 4 shared CPU game tests in our data. It is also 39.3% better value on MSRP (98.8 vs 71.0 PassMark/$), so the better CPU is not just faster, it is also the cleaner value play on paper.
Which one is more future-proof for 2026 and beyond?
EPYC 4545P is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2025 vs 2020), a healthier platform with AM5 and DDR5 instead of AM4, more multi-core headroom with 16 cores / 32 threads instead of 12/24, and AVX-512 support for heavier modern compute workloads. That should give you a better long-term upgrade path for motherboard, RAM, and future CPU swaps.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Path of Exile 2

Path of Exile 2

PresetEPYC 4545PRyzen 9 5900X
1080p
low286 FPS323 FPS
medium262 FPS291 FPS
high215 FPS243 FPS
ultra181 FPS193 FPS
1440p
low262 FPS307 FPS
medium218 FPS248 FPS
high167 FPS192 FPS
ultra148 FPS157 FPS
4K
low182 FPS193 FPS
medium151 FPS156 FPS
high115 FPS115 FPS
ultra102 FPS103 FPS
Counter-Strike 2

Counter-Strike 2

PresetEPYC 4545PRyzen 9 5900X
1080p
low674 FPS772 FPS
medium580 FPS647 FPS
high434 FPS508 FPS
ultra375 FPS450 FPS
1440p
low567 FPS619 FPS
medium506 FPS536 FPS
high392 FPS443 FPS
ultra312 FPS364 FPS
4K
low320 FPS365 FPS
medium289 FPS318 FPS
high255 FPS289 FPS
ultra219 FPS255 FPS
League of Legends

League of Legends

PresetEPYC 4545PRyzen 9 5900X
1080p
low850 FPS832 FPS
medium679 FPS645 FPS
high601 FPS558 FPS
ultra515 FPS459 FPS
1440p
low679 FPS721 FPS
medium543 FPS565 FPS
high469 FPS488 FPS
ultra398 FPS407 FPS
4K
low484 FPS511 FPS
medium401 FPS421 FPS
high360 FPS374 FPS
ultra302 FPS308 FPS
Valorant

Valorant

PresetEPYC 4545PRyzen 9 5900X
1080p
low1072 FPS974 FPS
medium966 FPS974 FPS
high843 FPS934 FPS
ultra760 FPS826 FPS
1440p
low842 FPS959 FPS
medium747 FPS843 FPS
high652 FPS726 FPS
ultra566 FPS617 FPS
4K
low619 FPS694 FPS
medium553 FPS621 FPS
high487 FPS541 FPS
ultra421 FPS437 FPS

Technical Specifications

Side-by-side comparison of EPYC 4545P and Ryzen 9 5900X

AMD

EPYC 4545P

The EPYC 4545P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 16 cores and 32 threads. Base frequency is 3 GHz, with boost up to 5.4 GHz. L3 cache: 64 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 65 Watt. Memory support: DDR5. Passmark benchmark score: 54,255 points. Launch price was $549.

AMD

Ryzen 9 5900X

The Ryzen 9 5900X is manufactured by AMD. It was released in 5 November 2020 (5 years ago). It is based on the Vermeer (Zen3) (2020−2022) architecture. It features 12 cores and 24 threads. Base frequency is 3.7 GHz, with boost up to 4.8 GHz. L3 cache: 64 MB. L2 cache: 512K (per core). Built on 7 nm, 12 nm process technology. Socket: AM4. Thermal design power (TDP): 105 Watt. Memory support: DDR4-3200. Passmark benchmark score: 38,955 points. Launch price was $549.

Processing Power

The EPYC 4545P packs 16 cores / 32 threads, while the Ryzen 9 5900X offers 12 cores / 24 threads — the EPYC 4545P has 4 more cores. Boost clocks reach 5.4 GHz on the EPYC 4545P versus 4.8 GHz on the Ryzen 9 5900X — a 11.8% clock advantage for the EPYC 4545P (base: 3 GHz vs 3.7 GHz). The EPYC 4545P uses the Grado (2025) architecture (4 nm), while the Ryzen 9 5900X uses Vermeer (Zen3) (2020−2022) (7 nm, 12 nm). In PassMark, the EPYC 4545P scores 54,255 against the Ryzen 9 5900X's 38,955 — a 32.8% lead for the EPYC 4545P. L3 cache: 64 MB (total) on the EPYC 4545P vs 64 MB on the Ryzen 9 5900X.

FeatureEPYC 4545PRyzen 9 5900X
Cores / Threads
16 / 32+33%
12 / 24
Boost Clock
5.4 GHz+13%
4.8 GHz
Base Clock
3 GHz
3.7 GHz+23%
L3 Cache
64 MB (total)
64 MB
L2 Cache
1 MB (per core)+100%
512K (per core)
Process
4 nm-43%
7 nm, 12 nm
Architecture
Grado (2025)
Vermeer (Zen3) (2020−2022)
PassMark
54,255+39%
38,955
Cinebench R23 Multi
21,000
Geekbench 6 Single
2,174
Geekbench 6 Multi
11,888
🧠

Memory & Platform

The EPYC 4545P uses the AM5 socket (PCIe 4.0), while the Ryzen 9 5900X uses AM4 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 5600 on the EPYC 4545P versus DDR4-3200 on the Ryzen 9 5900X — the EPYC 4545P supports 199.7% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 4545P supports up to 192 of RAM compared to 128 GB 40% more capacity for professional workloads. Both feature 2-channel memory with ECC support. PCIe lanes: 28 (EPYC 4545P) vs 24 (Ryzen 9 5900X) — the EPYC 4545P offers 4 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AM5 (EPYC 4545P) and A320,B350,X370,B450,X470,B550,X570 (Ryzen 9 5900X).

FeatureEPYC 4545PRyzen 9 5900X
Socket
AM5
AM4
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
5600+139900%
DDR4-3200
Max RAM Capacity
192
128 GB+69904967%
RAM Channels
2
2
ECC Support
Yes
Yes
PCIe Lanes
28+17%
24
🔧

Advanced Features

Both processors feature an unlocked multiplier for overclocking. Only the EPYC 4545P supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: VT-x, VT-d, AMD-V (EPYC 4545P) vs AMD-V (Ryzen 9 5900X). The EPYC 4545P includes integrated graphics (AMD Radeon Graphics), while the Ryzen 9 5900X requires a dedicated GPU. Primary use case: Ryzen 9 5900X targets Workstation. Direct competitor: EPYC 4545P rivals Ryzen 9 7900X; Ryzen 9 5900X rivals Core i9-12900K.

FeatureEPYC 4545PRyzen 9 5900X
Integrated GPU
Yes
No
IGPU Model
AMD Radeon Graphics
Unlocked
Yes
Yes
AVX-512
Yes
No
Virtualization
VT-x, VT-d, AMD-V
AMD-V
Target Use
Workstation
💰

Value Analysis

The EPYC 4545P launched at $549 MSRP, while the Ryzen 9 5900X debuted at $549. On MSRP ($549 vs $549), the Ryzen 9 5900X is $0 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 4545P delivers 98.8 pts/$ vs 71.0 pts/$ for the Ryzen 9 5900X — making the EPYC 4545P the 32.8% better value option.

FeatureEPYC 4545PRyzen 9 5900X
MSRP
$549
$549
Performance per Dollar
98.8+39%
71.0
Release Date
2025
2020