Radeon Instinct MI60 vs Radeon RX 5600

AMD

Radeon Instinct MI60

2018Core: 1200 MHzBoost: 1800 MHz

Popular choices:

VS
AMD

Radeon RX 5600

2020Core: 1035 MHzBoost: 1265 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Radeon Instinct MI60

2018

Why buy it

  • 45.2% more average FPS across 50 tracked games in our benchmark data.
  • 33.3% more VRAM for high-resolution textures and newer games (8 GB vs 6 GB).

Trade-offs

  • No equivalent frame-generation stack like FSR Frame Generation (2023).
  • Limited future-proofing: older hardware, 8 GB of VRAM, and weaker feature support mean it will age faster in upcoming AAA games.
  • 2520.1% HIGHER MSRP
    $6,000 MSRPvs$229 MSRP
  • Lower G3D Mark per dollar, at 1.9 vs 51.3 G3D/$ ($6,000 MSRP vs $229 MSRP).
  • 100% higher power demand at 300W vs 150W.

Radeon RX 5600

2020

Why buy it

  • Costs $5,771 less on MSRP ($229 MSRP vs $6,000 MSRP).
  • Delivers 2546% more G3D Mark for each dollar spent, at 51.3 vs 1.9 G3D/$ ($229 MSRP vs $6,000 MSRP).
  • Access to a newer frame-generation stack with FSR Frame Generation (2023).
  • More future proof: RDNA 1.0 (2019−2020) on 7nm with a newer platform for upcoming games.
  • Draws 150W instead of 300W, a 150W reduction.

Trade-offs

  • Lower average FPS than Radeon Instinct MI60 across 50 tracked games in our benchmark data.
  • Less VRAM, with 6 GB vs 8 GB for high-resolution textures and newer games.

Quick Answers

So, is Radeon RX 5600 better than Radeon Instinct MI60?
Yes. Radeon RX 5600 is the better GPU overall here. You are getting 1% higher PassMark G3D performance. It also comes from 2020 instead of 2018, which helps its case as the more complete modern gaming card.
Which one is more future-proof for 2026 and beyond?
Radeon RX 5600 is the more future-proof choice for 2026 and beyond. You are getting a newer 2020 generation instead of 2018 and better frame-generation support with FSR Frame Generation (2023) instead of FSR upscaling. That broader feature stack should age better as more games lean on modern upscaling and frame-generation support.
Which one is the smarter buy today, not just the cheaper card?
Radeon RX 5600 is the smarter buy today, but it is not as lopsided as a simple winner label makes it sound. Radeon RX 5600 is about $5,771 cheaper on MSRP at $229 MSRP versus $6,000 MSRP, and you are getting lower estimated average FPS across 50 tracked games in our benchmark data and 1.0% higher G3D Mark. It also leads G3D-per-dollar by 2546%. That is why the better overall card still comes out as the smarter buy today, not just the faster one.
Is Radeon Instinct MI60 still worth buying for gaming in 2026?
Yes. Radeon Instinct MI60 is still a strong modern gaming GPU: it is still comfortable for 1080p and decent for 1440p, though 4K is more situational. It remains a good buy when you can get it meaningfully cheaper than the alternative around $6,000 MSRP, even if Radeon RX 5600 is still the cleaner recommendation on overall value today.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetRadeon Instinct MI60Radeon RX 5600
1080p
low137 FPS80 FPS
medium117 FPS70 FPS
high101 FPS58 FPS
ultra70 FPS38 FPS
1440p
low108 FPS72 FPS
medium89 FPS63 FPS
high73 FPS47 FPS
ultra51 FPS30 FPS
4K
low50 FPS27 FPS
medium43 FPS25 FPS
high33 FPS17 FPS
ultra28 FPS15 FPS
Counter-Strike 2

Counter-Strike 2

PresetRadeon Instinct MI60Radeon RX 5600
1080p
low316 FPS211 FPS
medium274 FPS179 FPS
high224 FPS129 FPS
ultra180 FPS95 FPS
1440p
low214 FPS144 FPS
medium185 FPS119 FPS
high159 FPS88 FPS
ultra126 FPS63 FPS
4K
low101 FPS79 FPS
medium85 FPS66 FPS
high73 FPS52 FPS
ultra56 FPS36 FPS
League of Legends

League of Legends

PresetRadeon Instinct MI60Radeon RX 5600
1080p
low524 FPS529 FPS
medium419 FPS423 FPS
high349 FPS353 FPS
ultra262 FPS264 FPS
1440p
low393 FPS397 FPS
medium314 FPS317 FPS
high262 FPS264 FPS
ultra196 FPS198 FPS
4K
low262 FPS264 FPS
medium209 FPS212 FPS
high175 FPS176 FPS
ultra131 FPS132 FPS
Valorant

Valorant

PresetRadeon Instinct MI60Radeon RX 5600
1080p
low276 FPS247 FPS
medium237 FPS210 FPS
high202 FPS173 FPS
ultra164 FPS145 FPS
1440p
low211 FPS192 FPS
medium186 FPS170 FPS
high158 FPS135 FPS
ultra126 FPS111 FPS
4K
low125 FPS105 FPS
medium108 FPS88 FPS
high85 FPS71 FPS
ultra68 FPS56 FPS

Technical Specifications

Side-by-side comparison of Radeon Instinct MI60 and Radeon RX 5600

AMD

Radeon Instinct MI60

The Radeon Instinct MI60 is manufactured by AMD. It was released in November 18 2018. It features the GCN 5.1 architecture. The core clock ranges from 1200 MHz to 1800 MHz. It has 4096 shading units. The thermal design power (TDP) is 300W. Manufactured using 7 nm process technology. G3D Mark benchmark score: 11,638 points.

AMD

Radeon RX 5600

The Radeon RX 5600 is manufactured by AMD. It was released in July 7 2020. It features the RDNA 1.0 architecture. The core clock ranges from 1035 MHz to 1265 MHz. It has 2304 shading units. The thermal design power (TDP) is 150W. Manufactured using 7 nm process technology. G3D Mark benchmark score: 11,753 points.

Graphics Performance

The Radeon Instinct MI60 scores 11,638 and the Radeon RX 5600 reaches 11,753 in the G3D Mark benchmark — just a 1% difference, making them near-identical in rasterization performance. The Radeon Instinct MI60 is built on GCN 5.1 while the Radeon RX 5600 uses RDNA 1.0, both on a 7 nm process. Shader units: 4,096 (Radeon Instinct MI60) vs 2,304 (Radeon RX 5600). Raw compute: 14.75 TFLOPS (Radeon Instinct MI60) vs 5.829 TFLOPS (Radeon RX 5600). Boost clocks: 1800 MHz vs 1265 MHz.

FeatureRadeon Instinct MI60Radeon RX 5600
G3D Mark Score
11,638
11,753
Architecture
GCN 5.1
RDNA 1.0
Process Node
7 nm
7 nm
Shading Units
4096+78%
2304
Compute (TFLOPS)
14.75 TFLOPS+153%
5.829 TFLOPS
Boost Clock
1800 MHz+42%
1265 MHz
ROPs
64
64
TMUs
256+78%
144
L2 Cache
4 MB+33%
3 MB
Frame Generation
FSR upscaling
FSR upscaling + limited Frame Generation

Advanced Features (DLSS/FSR)

A critical advantage for the Radeon RX 5600 is support for FSR Frame Generation. This allows it to generate entire frames using AI/Algorithms, essentially doubling the frame rate in CPU-bound scenarios or heavy ray-tracing titles. The Radeon Instinct MI60 lacks specific hardware/driver support for this native frame generation tier.

FeatureRadeon Instinct MI60Radeon RX 5600
Upscaling Tech
FSR Upscaling / FSR 4
FSR Upscaling / FSR 4
Frame Generation
Not Supported
FSR Frame Generation
Ray Reconstruction
No
No
Low Latency
AMD Anti-Lag
AMD Anti-Lag
💾

Video Memory (VRAM)

The Radeon Instinct MI60 comes with 8 GB of VRAM, while the Radeon RX 5600 has 6 GB. The Radeon Instinct MI60 offers 33.3% more capacity, crucial for higher resolutions and texture-heavy games. Bus width: 128-bit vs 192-bit. L2 Cache: 4 MB (Radeon Instinct MI60) vs 3 MB (Radeon RX 5600) — the Radeon Instinct MI60 has significantly larger on-die cache to reduce VRAM reliance.

FeatureRadeon Instinct MI60Radeon RX 5600
VRAM Capacity
8 GB+33%
6 GB
Memory Type
GDDR6
GDDR6
Bus Width
128-bit
192-bit+50%
L2 Cache
4 MB+33%
3 MB
🖥️

Display & API Support

DirectX support: 12.1 (Radeon Instinct MI60) vs 12.1 (Radeon RX 5600). Vulkan: 1.3 vs 1.2. OpenGL: 4.5 vs 4.6. Maximum simultaneous displays: 1 vs 4.

FeatureRadeon Instinct MI60Radeon RX 5600
DirectX
12.1
12.1
Vulkan
1.3+8%
1.2
OpenGL
4.5
4.6+2%
Max Displays
1
4+300%
🎬

Media & Encoding

Hardware encoder: VCE 4.1 (Radeon Instinct MI60) vs VCN 2.0 (Radeon RX 5600). Decoder: UVD 7.2 vs VCN 2.0. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Radeon Instinct MI60) vs MPEG-2,H.264,HEVC,VP9 (Radeon RX 5600).

FeatureRadeon Instinct MI60Radeon RX 5600
Encoder
VCE 4.1
VCN 2.0
Decoder
UVD 7.2
VCN 2.0
Codecs
MPEG-2,H.264,HEVC,VP9
MPEG-2,H.264,HEVC,VP9
🔌

Power & Dimensions

The Radeon Instinct MI60 draws 300W versus the Radeon RX 5600's 150W — a 66.7% difference. The Radeon RX 5600 is more power-efficient. Recommended PSU: 500W (Radeon Instinct MI60) vs 500W (Radeon RX 5600). Power connectors: PCIe-powered vs PCIe-powered. Card length: 267mm vs 241mm, occupying 2 vs 2 slots. Typical load temperature: 85°C vs 80°C.

FeatureRadeon Instinct MI60Radeon RX 5600
TDP
300W
150W-50%
Recommended PSU
500W
500W
Power Connector
PCIe-powered
PCIe-powered
Length
267mm
241mm
Height
111mm
111mm
Slots
2
2
Temp (Load)
85°C
80°C-6%
Perf/Watt
38.8
78.4+102%
💰

Value Analysis

The Radeon Instinct MI60 launched at $6000 MSRP, while the Radeon RX 5600 launched at $229. The Radeon RX 5600 costs 96.2% less ($5771 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 1.9 (Radeon Instinct MI60) vs 51.3 (Radeon RX 5600) — the Radeon RX 5600 offers 2600% better value. The Radeon RX 5600 is the newer GPU (2020 vs 2018).

FeatureRadeon Instinct MI60Radeon RX 5600
MSRP
$6000
$229-96%
Performance per Dollar
1.9
51.3+2600%
Codename
Vega 20
Navi 10
Release
November 18 2018
July 7 2020
Ranking
#232
#295