Ryzen Threadripper PRO 3975WX vs Xeon Platinum 8380

AMD

Ryzen Threadripper PRO 3975WX

32 Cores64 Thrd280 WWMax: 4.2 GHz2020

Popular choices:

VS
Intel

Xeon Platinum 8380

40 Cores80 Thrd270 WWMax: 3.4 GHz2021

Popular choices:

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

Ryzen Threadripper PRO 3975WX

2020

Why buy it

  • +113.3% larger total L3 cache (128 MB vs 60 MB).
  • Costs $673 less on MSRP ($1,337 MSRP vs $2,010 MSRP).
  • Delivers 50.2% more PassMark for each dollar spent, at 46.6 vs 31.0 PassMark/$ ($1,337 MSRP vs $2,010 MSRP).
  • 100% more PCIe lanes (128 vs 64) for storage and expansion-heavy builds.

Trade-offs

  • Worse for gaming: lower average FPS than Xeon Platinum 8380 across 4 shared CPU benchmark tests.
  • Lower Geekbench multi-core (25,211 vs 40,000).
  • No AVX-512 support for niche heavy compute workloads where it can matter.

Xeon Platinum 8380

2021

Why buy it

  • Better for gaming: +6.7% higher average FPS across 4 shared CPU benchmark tests.
  • Draws 270W instead of 280W, a 10W reduction.
  • AVX-512 support for select workstation, AI, and scientific workloads.

Trade-offs

  • Smaller total L3 cache (60 MB vs 128 MB).
  • Lower PassMark per dollar, at 31.0 vs 46.6 PassMark/$ ($2,010 MSRP vs $1,337 MSRP).

Quick Answers

So, is Xeon Platinum 8380 better than Ryzen Threadripper PRO 3975WX?
Yes. Xeon Platinum 8380 is the better overall CPU here. You are getting a 6.7% average FPS lead across 4 shared CPU game tests in our data, 58.7% better Geekbench multi-core, 0.1% higher PassMark, and the stronger long-term platform, which makes it the stronger all-around choice.
Which one is better for gaming?
If gaming is the priority, Xeon Platinum 8380 is the better pick here. According to our tests, it delivers 6.7% more average FPS across 4 shared CPU game tests.
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, Xeon Platinum 8380 is the better fit. You are getting 58.7% better Geekbench multi-core, backed by 40 cores and 80 threads.
Which one is the smarter buy today, not just the cheaper CPU?
Xeon Platinum 8380 is still the faster CPU overall, but Ryzen Threadripper PRO 3975WX makes more sense if price matters more than absolute performance. Xeon Platinum 8380 is 50.3% more expensive on MSRP at $2,010 MSRP versus $1,337 MSRP, and it gives you a 6.7% average FPS lead across 4 shared CPU game tests in our data. Ryzen Threadripper PRO 3975WX is also 50.2% better value on MSRP (46.6 vs 31.0 PassMark/$), which is why it is easier to justify for price-conscious builds on paper.
Which one is more future-proof for 2026 and beyond?
Xeon Platinum 8380 is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2021 vs 2020), more multi-core headroom with 40 cores / 80 threads instead of 32/64, and AVX-512 support for heavier modern compute workloads. That extra compute headroom should age better as games, background tasks, and creator workloads get heavier.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Path of Exile 2

Path of Exile 2

PresetRyzen Threadripper PRO 3975WXXeon Platinum 8380
1080p
low183 FPS185 FPS
medium149 FPS149 FPS
high126 FPS120 FPS
ultra98 FPS94 FPS
1440p
low160 FPS154 FPS
medium127 FPS120 FPS
high101 FPS93 FPS
ultra79 FPS74 FPS
4K
low73 FPS72 FPS
medium61 FPS60 FPS
high48 FPS46 FPS
ultra40 FPS38 FPS
Counter-Strike 2

Counter-Strike 2

PresetRyzen Threadripper PRO 3975WXXeon Platinum 8380
1080p
low579 FPS412 FPS
medium499 FPS361 FPS
high383 FPS294 FPS
ultra327 FPS235 FPS
1440p
low485 FPS353 FPS
medium425 FPS314 FPS
high338 FPS264 FPS
ultra274 FPS203 FPS
4K
low304 FPS219 FPS
medium270 FPS198 FPS
high231 FPS167 FPS
ultra202 FPS135 FPS
League of Legends

League of Legends

PresetRyzen Threadripper PRO 3975WXXeon Platinum 8380
1080p
low681 FPS935 FPS
medium564 FPS817 FPS
high497 FPS766 FPS
ultra425 FPS680 FPS
1440p
low570 FPS746 FPS
medium479 FPS643 FPS
high424 FPS603 FPS
ultra364 FPS535 FPS
4K
low417 FPS479 FPS
medium333 FPS378 FPS
high293 FPS334 FPS
ultra234 FPS272 FPS
Valorant

Valorant

PresetRyzen Threadripper PRO 3975WXXeon Platinum 8380
1080p
low1020 FPS900 FPS
medium917 FPS817 FPS
high765 FPS705 FPS
ultra664 FPS606 FPS
1440p
low802 FPS703 FPS
medium701 FPS617 FPS
high584 FPS530 FPS
ultra496 FPS454 FPS
4K
low559 FPS507 FPS
medium504 FPS454 FPS
high437 FPS398 FPS
ultra373 FPS346 FPS

Technical Specifications

Side-by-side comparison of Ryzen Threadripper PRO 3975WX and Xeon Platinum 8380

AMD

Ryzen Threadripper PRO 3975WX

The Ryzen Threadripper PRO 3975WX is manufactured by AMD. It was released in 2020-07-14. It is based on the Matisse (2019−2020) architecture. It features 32 cores and 64 threads. Base frequency is 3.5 GHz, with boost up to 4.2 GHz. L3 cache: 128 MB. L2 cache: 512K (per core). Built on 7 nm, 12 nm process technology. Socket: sWRX8. Thermal design power (TDP): 280 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,261 points. Launch price was $4,499.

Intel

Xeon Platinum 8380

The Xeon Platinum 8380 is manufactured by Intel. It was released in 2021-04-06. It is based on the Ice Lake-SP (2021) architecture. It features 40 cores and 80 threads. Base frequency is 2.3 GHz, with boost up to 3.4 GHz. L3 cache: 60 MB (total). L2 cache: 1 MB (per core). Built on 10 nm process technology. Socket: LGA4189. Thermal design power (TDP): 270 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,318 points. Launch price was $5,846.

Processing Power

The Ryzen Threadripper PRO 3975WX packs 32 cores / 64 threads, while the Xeon Platinum 8380 offers 40 cores / 80 threads — the Xeon Platinum 8380 has 8 more cores. Boost clocks reach 4.2 GHz on the Ryzen Threadripper PRO 3975WX versus 3.4 GHz on the Xeon Platinum 8380 — a 21.1% clock advantage for the Ryzen Threadripper PRO 3975WX (base: 3.5 GHz vs 2.3 GHz). The Ryzen Threadripper PRO 3975WX uses the Matisse (2019−2020) architecture (7 nm, 12 nm), while the Xeon Platinum 8380 uses Ice Lake-SP (2021) (10 nm). In PassMark, the Ryzen Threadripper PRO 3975WX scores 62,261 against the Xeon Platinum 8380's 62,318 — a 0.1% lead for the Xeon Platinum 8380. Geekbench 6 single-core — the metric most relevant to gaming — records 1,260 vs 1,300, a 3.1% lead for the Xeon Platinum 8380 that directly translates to higher frame rates. Multi-core Geekbench: 25,211 vs 40,000 (45.4% advantage for the Xeon Platinum 8380). L3 cache: 128 MB on the Ryzen Threadripper PRO 3975WX vs 60 MB (total) on the Xeon Platinum 8380.

FeatureRyzen Threadripper PRO 3975WXXeon Platinum 8380
Cores / Threads
32 / 64
40 / 80+25%
Boost Clock
4.2 GHz+24%
3.4 GHz
Base Clock
3.5 GHz+52%
2.3 GHz
L3 Cache
128 MB+113%
60 MB (total)
L2 Cache
512K (per core)
1 MB (per core)+100%
Process
7 nm, 12 nm-30%
10 nm
Architecture
Matisse (2019−2020)
Ice Lake-SP (2021)
PassMark
62,261
62,318
Cinebench R23 Multi
42,986
Geekbench 6 Single
1,260
1,300+3%
Geekbench 6 Multi
25,211
40,000+59%
🧠

Memory & Platform

The Ryzen Threadripper PRO 3975WX uses the sWRX8 socket (PCIe 4.0), while the Xeon Platinum 8380 uses LGA4189 (PCIe 4.0) — making them incompatible on the same motherboard. Both support up to DDR4-3200 memory speed. The Xeon Platinum 8380 supports up to 6144 GB of RAM compared to 2048 GB 100% more capacity for professional workloads. Both feature 8-channel memory with ECC support. PCIe lanes: 128 (Ryzen Threadripper PRO 3975WX) vs 64 (Xeon Platinum 8380) — the Ryzen Threadripper PRO 3975WX offers 64 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AMD WRX80 (Ryzen Threadripper PRO 3975WX) and C621A (Xeon Platinum 8380).

FeatureRyzen Threadripper PRO 3975WXXeon Platinum 8380
Socket
sWRX8
LGA4189
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
DDR4-3200
DDR4-3200
Max RAM Capacity
2048 GB
6144 GB+200%
RAM Channels
8
8
ECC Support
Yes
Yes
PCIe Lanes
128+100%
64
🔧

Advanced Features

Only the Ryzen Threadripper PRO 3975WX has an unlocked multiplier for overclocking — a significant advantage for enthusiasts seeking extra performance. Only the Xeon Platinum 8380 supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: true (Ryzen Threadripper PRO 3975WX) vs VT-x, VT-d (Xeon Platinum 8380). Primary use case: Xeon Platinum 8380 targets Datacenter. Direct competitor: Ryzen Threadripper PRO 3975WX rivals Xeon W-3375; Xeon Platinum 8380 rivals EPYC 7543.

FeatureRyzen Threadripper PRO 3975WXXeon Platinum 8380
Integrated GPU
No
No
IGPU Model
None
None
Unlocked
Yes
No
AVX-512
No
Yes
Virtualization
true
VT-x, VT-d
Target Use
Datacenter
💰

Value Analysis

The Ryzen Threadripper PRO 3975WX launched at $1337 MSRP, while the Xeon Platinum 8380 debuted at $2010. On MSRP ($1337 vs $2010), the Ryzen Threadripper PRO 3975WX is $673 cheaper. In terms of value on MSRP (PassMark points per dollar), the Ryzen Threadripper PRO 3975WX delivers 46.6 pts/$ vs 31.0 pts/$ for the Xeon Platinum 8380 — making the Ryzen Threadripper PRO 3975WX the 40.1% better value option.

FeatureRyzen Threadripper PRO 3975WXXeon Platinum 8380
MSRP
$1337-33%
$2010
Performance per Dollar
46.6+50%
31.0
Release Date
2020
2021