Quadro RTX 4000 vs Radeon RX 6600

NVIDIA

Quadro RTX 4000

2018Core: 1005 MHzBoost: 1545 MHz

Popular choices:

VS
AMD

Radeon RX 6600

2021Core: 1626 MHzBoost: 2491 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Quadro RTX 4000

2018

Why buy it

  • Access to DLSS 3.5 Super Resolution (2023).

Trade-offs

  • Lower average FPS than Radeon RX 6600 across 50 tracked games in our benchmark data.
  • Weaker long-term outlook: Radeon RX 6600 is the safer future-proof pick thanks to newer hardware and better gaming feature support.
  • 173.3% HIGHER MSRP
    $899 MSRPvs$329 MSRP
  • Lower G3D Mark per dollar, at 16.6 vs 45.9 G3D/$ ($899 MSRP vs $329 MSRP).
  • 21.2% higher power demand at 160W vs 132W.

Radeon RX 6600

2021

Why buy it

  • 1.3% more average FPS across 50 tracked games in our benchmark data.
  • Costs $570 less on MSRP ($329 MSRP vs $899 MSRP).
  • Delivers 176.3% more G3D Mark for each dollar spent, at 45.9 vs 16.6 G3D/$ ($329 MSRP vs $899 MSRP).
  • More future proof: RDNA 2.0 (2020−2025) on 7nm with a newer platform for upcoming games.
  • Draws 132W instead of 160W, a 28W reduction.

Trade-offs

  • No DLSS support; it relies on FSR 3 (2023) instead.

Quick Answers

So, is Radeon RX 6600 better than Quadro RTX 4000?
Yes. Radeon RX 6600 is clearly the better overall GPU here. Radeon RX 6600 averages 1.3% more FPS across 50 tracked games in our benchmark data. You are also looking at 15,089 vs 14,925 in G3D Mark. On top of that, Radeon RX 6600 is a 2021 card with FSR 3 + AFMF, while Quadro RTX 4000 is a 2018 model from an older generation with DLSS 3.5 + Frame Generation. So this is not really a tight same-tier comparison. It is more a modern card against an older, weaker alternative.
Which one is more future-proof for 2026 and beyond?
Radeon RX 6600 is the more future-proof choice for 2026 and beyond. You are getting a newer 2021 generation instead of 2018, better frame-generation support with FSR Frame Generation + AFMF (2023) instead of DLSS 3.5 + Frame Generation (2023), and a 7nm process instead of 12nm. That broader feature stack should age better as more games lean on modern upscaling and frame-generation support.
Which one is the smarter buy today, not just the cheaper card?
Radeon RX 6600 can still make sense if you find it at the right price, especially around $329 MSRP. Radeon RX 6600 is still the smarter buy for most people, though, because the raw performance is close while the overall package is cleaner. Radeon RX 6600 is about $570 cheaper on MSRP at $329 MSRP versus $899 MSRP, and you are getting 1.3% more estimated average FPS across 50 tracked games in our benchmark data and 1.1% higher G3D Mark. Moving to $329 MSRP gets you newer hardware, lower power draw (132W vs 160W), and FSR 3 + AFMF.
Is Quadro RTX 4000 still worth buying for gaming in 2026?
Yes. Quadro RTX 4000 is still a strong gaming card in 2026: it is very strong for 1080p, good for 1440p, and more limited at 4K. Price is really the swing factor here. If you find it at or below $899 MSRP, it remains a very sensible buy. Radeon RX 6600 is still the safer recommendation for most fresh builds because it offers a cleaner overall package with newer hardware and FSR 3 + AFMF.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetQuadro RTX 4000Radeon RX 6600
1080p
low129 FPS167 FPS
medium111 FPS147 FPS
high92 FPS130 FPS
ultra63 FPS110 FPS
1440p
low105 FPS140 FPS
medium87 FPS114 FPS
high67 FPS101 FPS
ultra46 FPS91 FPS
4K
low46 FPS84 FPS
medium40 FPS71 FPS
high28 FPS58 FPS
ultra24 FPS51 FPS
Counter-Strike 2

Counter-Strike 2

PresetQuadro RTX 4000Radeon RX 6600
1080p
low270 FPS332 FPS
medium225 FPS276 FPS
high185 FPS217 FPS
ultra156 FPS166 FPS
1440p
low203 FPS210 FPS
medium168 FPS174 FPS
high136 FPS140 FPS
ultra109 FPS111 FPS
4K
low117 FPS103 FPS
medium100 FPS85 FPS
high80 FPS73 FPS
ultra58 FPS55 FPS
League of Legends

League of Legends

PresetQuadro RTX 4000Radeon RX 6600
1080p
low672 FPS644 FPS
medium537 FPS512 FPS
high448 FPS431 FPS
ultra336 FPS340 FPS
1440p
low504 FPS489 FPS
medium403 FPS406 FPS
high336 FPS332 FPS
ultra252 FPS255 FPS
4K
low336 FPS331 FPS
medium269 FPS271 FPS
high224 FPS202 FPS
ultra168 FPS161 FPS
Valorant

Valorant

PresetQuadro RTX 4000Radeon RX 6600
1080p
low248 FPS535 FPS
medium215 FPS468 FPS
high172 FPS380 FPS
ultra145 FPS313 FPS
1440p
low190 FPS408 FPS
medium168 FPS349 FPS
high132 FPS259 FPS
ultra108 FPS211 FPS
4K
low113 FPS240 FPS
medium95 FPS211 FPS
high77 FPS187 FPS
ultra58 FPS143 FPS

Technical Specifications

Side-by-side comparison of Quadro RTX 4000 and Radeon RX 6600

NVIDIA

Quadro RTX 4000

The Quadro RTX 4000 is manufactured by NVIDIA. It was released in November 13 2018. It features the Turing architecture. The core clock ranges from 1005 MHz to 1545 MHz. It has 2304 shading units. The thermal design power (TDP) is 160W. Manufactured using 12 nm process technology. It features 36 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 14,925 points. Launch price was $899.

AMD

Radeon RX 6600

The Radeon RX 6600 is manufactured by AMD. It was released in October 13 2021. It features the RDNA 2.0 architecture. The core clock ranges from 1626 MHz to 2491 MHz. It has 1792 shading units. The thermal design power (TDP) is 132W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 15,089 points. Launch price was $329.

Graphics Performance

The Quadro RTX 4000 scores 14,925 and the Radeon RX 6600 reaches 15,089 in the G3D Mark benchmark — just a 1.1% difference, making them near-identical in rasterization performance. The Quadro RTX 4000 is built on Turing while the Radeon RX 6600 uses RDNA 2.0, both on 12 nm vs 7 nm. Shader units: 2,304 (Quadro RTX 4000) vs 1,792 (Radeon RX 6600). Raw compute: 7.119 TFLOPS (Quadro RTX 4000) vs 8.928 TFLOPS (Radeon RX 6600). Boost clocks: 1545 MHz vs 2491 MHz. Ray tracing: 36 RT cores (Quadro RTX 4000) vs 28 (Radeon RX 6600) with 288 Tensor cores.

FeatureQuadro RTX 4000Radeon RX 6600
G3D Mark Score
14,925
15,089+1%
Architecture
Turing
RDNA 2.0
Process Node
12 nm
7 nm
Shading Units
2304+29%
1792
Compute (TFLOPS)
7.119 TFLOPS
8.928 TFLOPS+25%
Boost Clock
1545 MHz
2491 MHz+61%
ROPs
64
64
TMUs
144+29%
112
L1 Cache
2.3 MB+360%
0.5 MB
L2 Cache
4 MB+100%
2 MB
Ray Tracing Cores
36+29%
28

Advanced Features (DLSS/FSR)

Both GPUs support Frame Generation technologies, but they achieve it differently. The Quadro RTX 4000 uses DLSS 3.5 + Frame Generation, while the Radeon RX 6600 relies on FSR Frame Generation + AFMF. Both can significantly boost FPS in supported titles, but they are not on the same feature stack.The Quadro RTX 4000 gives access to NVIDIA DLSS (Deep Learning Super Sampling), widely regarding as the superior upscaling method for image quality. The Radeon RX 6600 relies on FSR (FidelityFX Super Resolution), which is capable but generally slightly noisier than DLSS in motion.

FeatureQuadro RTX 4000Radeon RX 6600
Upscaling Tech
DLSS 3.5 Super Resolution
FSR 3
Frame Generation
DLSS 3.5 + Frame Generation
FSR Frame Generation + AFMF
Ray Reconstruction
Yes (DLSS 3.5)
No
Low Latency
NVIDIA Reflex
AMD Anti-Lag
💾

Video Memory (VRAM)

Both cards feature 8 GB of GDDR6. Memory bandwidth: 448 GB/s (Quadro RTX 4000) vs 224 GB/s (Radeon RX 6600) — a 100% advantage for the Quadro RTX 4000. Bus width: 256-bit vs 128-bit. L2 Cache: 4 MB (Quadro RTX 4000) vs 2 MB (Radeon RX 6600) — the Quadro RTX 4000 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro RTX 4000Radeon RX 6600
VRAM Capacity
8 GB
8 GB
Memory Type
GDDR6
GDDR6
Memory Bandwidth
448 GB/s+100%
224 GB/s
Bus Width
256-bit+100%
128-bit
L2 Cache
4 MB+100%
2 MB
🖥️

Display & API Support

DirectX support: 12.2 (Quadro RTX 4000) vs 12 Ultimate (Radeon RX 6600). Vulkan: 1.1 vs 1.4. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 4.

FeatureQuadro RTX 4000Radeon RX 6600
DirectX
12.2+2%
12 Ultimate
Vulkan
1.1
1.4+27%
OpenGL
4.6
4.6
Max Displays
4
4
🎬

Media & Encoding

Hardware encoder: NVENC 7.0 (Quadro RTX 4000) vs VCE (Radeon RX 6600). Decoder: PureVideo HD VP10 vs UVD. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro RTX 4000) vs H.264,H.265/HEVC,AV1 (Radeon RX 6600).

FeatureQuadro RTX 4000Radeon RX 6600
Encoder
NVENC 7.0
VCE
Decoder
PureVideo HD VP10
UVD
Codecs
MPEG-2,H.264,HEVC,VP9
H.264,H.265/HEVC,AV1
🔌

Power & Dimensions

The Quadro RTX 4000 draws 160W versus the Radeon RX 6600's 132W — a 19.2% difference. The Radeon RX 6600 is more power-efficient. Recommended PSU: 500W (Quadro RTX 4000) vs 450W (Radeon RX 6600). Power connectors: PCIe-powered vs 1x 8-pin. Card length: 241mm vs 190mm, occupying 2 vs 2 slots. Typical load temperature: 80°C vs 70°C.

FeatureQuadro RTX 4000Radeon RX 6600
TDP
160W
132W-18%
Recommended PSU
500W
450W-10%
Power Connector
PCIe-powered
1x 8-pin
Length
241mm
190mm
Height
111mm
110mm
Slots
2
2
Temp (Load)
80°C
70°C-13%
Perf/Watt
93.3
114.3+23%
💰

Value Analysis

The Quadro RTX 4000 launched at $899 MSRP, while the Radeon RX 6600 launched at $329. The Radeon RX 6600 costs 63.4% less ($570 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 16.6 (Quadro RTX 4000) vs 45.9 (Radeon RX 6600) — the Radeon RX 6600 offers 176.5% better value. The Radeon RX 6600 is the newer GPU (2021 vs 2018).

FeatureQuadro RTX 4000Radeon RX 6600
MSRP
$899
$329-63%
Performance per Dollar
16.6
45.9+177%
Codename
TU104
Navi 23
Release
November 13 2018
October 13 2021
Ranking
#154
#150