Quadro RTX 4000 vs Radeon RX 6650M

NVIDIA

Quadro RTX 4000

2018Core: 1005 MHzBoost: 1545 MHz

Popular choices:

VS
AMD

Radeon RX 6650M

2022Core: 2068 MHzBoost: 2416 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Quadro RTX 4000

2018

Why buy it

  • Delivers 100+% more G3D Mark for each dollar spent, at 16.6 vs 0 G3D/$ ($899 MSRP vs Unknown MSRP).
  • Access to DLSS 3.5 Super Resolution (2023).

Trade-offs

  • Lower average FPS than Radeon RX 6650M across 40 tracked games in our benchmark data.
  • Weaker long-term outlook: Radeon RX 6650M is the safer future-proof pick thanks to newer hardware and better gaming feature support.
  • 33.3% higher power demand at 160W vs 120W.

Radeon RX 6650M

2022

Why buy it

  • 3.7% more average FPS across 40 tracked games in our benchmark data.
  • More future proof: RDNA 2.0 on 7nm with a newer platform for upcoming games.
  • Draws 120W instead of 160W, a 40W reduction.

Trade-offs

  • No DLSS support; it relies on FSR 3 (2023) instead.
  • Lower G3D Mark per dollar, at 0 vs 16.6 G3D/$ (Unknown MSRP vs $899 MSRP).

Quick Answers

So, is Radeon RX 6650M better than Quadro RTX 4000?
Yes. Radeon RX 6650M is clearly the better overall GPU here. Radeon RX 6650M averages 3.7% more FPS across 40 tracked games in our benchmark data. You are also looking at 15,171 vs 14,925 in G3D Mark. On top of that, Radeon RX 6650M is a 2022 card with FSR 3 + AFMF, while Quadro RTX 4000 is a 2018 model from an older generation with DLSS 3.5 + Frame Generation. So this is not really a tight same-tier comparison. It is more a modern card against an older, weaker alternative.
Which one is more future-proof for 2026 and beyond?
Radeon RX 6650M is the more future-proof choice for 2026 and beyond. You are getting a newer 2022 generation instead of 2018, better frame-generation support with FSR Frame Generation + AFMF (2023) instead of DLSS 3.5 + Frame Generation (2023), and a 7nm process instead of 12nm. That broader feature stack should age better as more games lean on modern upscaling and frame-generation support.
Which one is the smarter buy today, not just the cheaper card?
Quadro RTX 4000 can still make sense if you find it at the right price, especially around $899 MSRP. Radeon RX 6650M is still the smarter buy for most people, though, because the raw performance is close while the overall package is cleaner. Radeon RX 6650M is priced in an unclear MSRP range at an unclear MSRP versus $899 MSRP, and you are getting 3.7% more estimated average FPS across 40 tracked games in our benchmark data and 1.6% higher G3D Mark. Moving to an unclear MSRP gets you newer hardware, lower power draw (120W vs 160W), and FSR 3 + AFMF.
Is Quadro RTX 4000 still worth buying for gaming in 2026?
Yes. Quadro RTX 4000 is still a strong gaming card in 2026: it is very strong for 1080p, good for 1440p, and more limited at 4K. Price is really the swing factor here. If you find it at or below $899 MSRP, it remains a very sensible buy. Radeon RX 6650M is still the safer recommendation for most fresh builds because it offers a cleaner overall package with newer hardware and FSR 3 + AFMF.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetQuadro RTX 4000Radeon RX 6650M
1080p
low129 FPS167 FPS
medium111 FPS148 FPS
high92 FPS131 FPS
ultra63 FPS111 FPS
1440p
low105 FPS140 FPS
medium87 FPS113 FPS
high67 FPS101 FPS
ultra46 FPS91 FPS
4K
low46 FPS84 FPS
medium40 FPS71 FPS
high28 FPS58 FPS
ultra24 FPS50 FPS
Counter-Strike 2

Counter-Strike 2

PresetQuadro RTX 4000Radeon RX 6650M
1080p
low270 FPS305 FPS
medium225 FPS255 FPS
high185 FPS201 FPS
ultra156 FPS156 FPS
1440p
low203 FPS195 FPS
medium168 FPS163 FPS
high136 FPS129 FPS
ultra109 FPS103 FPS
4K
low117 FPS105 FPS
medium100 FPS87 FPS
high80 FPS74 FPS
ultra58 FPS56 FPS
League of Legends

League of Legends

PresetQuadro RTX 4000Radeon RX 6650M
1080p
low672 FPS652 FPS
medium537 FPS518 FPS
high448 FPS435 FPS
ultra336 FPS341 FPS
1440p
low504 FPS495 FPS
medium403 FPS410 FPS
high336 FPS336 FPS
ultra252 FPS256 FPS
4K
low336 FPS333 FPS
medium269 FPS272 FPS
high224 FPS206 FPS
ultra168 FPS166 FPS
Valorant

Valorant

PresetQuadro RTX 4000Radeon RX 6650M
1080p
low248 FPS473 FPS
medium215 FPS394 FPS
high172 FPS330 FPS
ultra145 FPS277 FPS
1440p
low190 FPS371 FPS
medium168 FPS306 FPS
high132 FPS243 FPS
ultra108 FPS198 FPS
4K
low113 FPS212 FPS
medium95 FPS171 FPS
high77 FPS160 FPS
ultra58 FPS124 FPS

Technical Specifications

Side-by-side comparison of Quadro RTX 4000 and Radeon RX 6650M

NVIDIA

Quadro RTX 4000

The Quadro RTX 4000 is manufactured by NVIDIA. It was released in November 13 2018. It features the Turing architecture. The core clock ranges from 1005 MHz to 1545 MHz. It has 2304 shading units. The thermal design power (TDP) is 160W. Manufactured using 12 nm process technology. It features 36 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 14,925 points. Launch price was $899.

AMD

Radeon RX 6650M

The Radeon RX 6650M is manufactured by AMD. It was released in January 4 2022. It features the RDNA 2.0 architecture. The core clock ranges from 2068 MHz to 2416 MHz. It has 1792 shading units. The thermal design power (TDP) is 120W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 15,171 points.

Graphics Performance

The Quadro RTX 4000 scores 14,925 and the Radeon RX 6650M reaches 15,171 in the G3D Mark benchmark — just a 1.6% difference, making them near-identical in rasterization performance. The Quadro RTX 4000 is built on Turing while the Radeon RX 6650M uses RDNA 2.0, both on 12 nm vs 7 nm. Shader units: 2,304 (Quadro RTX 4000) vs 1,792 (Radeon RX 6650M). Raw compute: 7.119 TFLOPS (Quadro RTX 4000) vs 8.659 TFLOPS (Radeon RX 6650M). Boost clocks: 1545 MHz vs 2416 MHz. Ray tracing: 36 RT cores (Quadro RTX 4000) vs 28 (Radeon RX 6650M) with 288 Tensor cores.

FeatureQuadro RTX 4000Radeon RX 6650M
G3D Mark Score
14,925
15,171+2%
Architecture
Turing
RDNA 2.0
Process Node
12 nm
7 nm
Shading Units
2304+29%
1792
Compute (TFLOPS)
7.119 TFLOPS
8.659 TFLOPS+22%
Boost Clock
1545 MHz
2416 MHz+56%
ROPs
64
64
TMUs
144+29%
112
L1 Cache
2.3 MB+360%
0.5 MB
L2 Cache
4 MB+100%
2 MB
Ray Tracing Cores
36+29%
28

Advanced Features (DLSS/FSR)

Both GPUs support Frame Generation technologies, but they achieve it differently. The Quadro RTX 4000 uses DLSS 3.5 + Frame Generation, while the Radeon RX 6650M relies on FSR Frame Generation + AFMF. Both can significantly boost FPS in supported titles, but they are not on the same feature stack.The Quadro RTX 4000 gives access to NVIDIA DLSS (Deep Learning Super Sampling), widely regarding as the superior upscaling method for image quality. The Radeon RX 6650M relies on FSR (FidelityFX Super Resolution), which is capable but generally slightly noisier than DLSS in motion.

FeatureQuadro RTX 4000Radeon RX 6650M
Upscaling Tech
DLSS 3.5 Super Resolution
FSR 3
Frame Generation
DLSS 3.5 + Frame Generation
FSR Frame Generation + AFMF
Ray Reconstruction
Yes (DLSS 3.5)
No
Low Latency
NVIDIA Reflex
AMD Anti-Lag
💾

Video Memory (VRAM)

Both cards feature 8 GB of GDDR6. Memory bandwidth: 448 GB/s (Quadro RTX 4000) vs 224 GB/s (Radeon RX 6650M) — a 100% advantage for the Quadro RTX 4000. Bus width: 256-bit vs 128-bit. L2 Cache: 4 MB (Quadro RTX 4000) vs 2 MB (Radeon RX 6650M) — the Quadro RTX 4000 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro RTX 4000Radeon RX 6650M
VRAM Capacity
8 GB
8 GB
Memory Type
GDDR6
GDDR6
Memory Bandwidth
448 GB/s+100%
224 GB/s
Bus Width
256-bit+100%
128-bit
L2 Cache
4 MB+100%
2 MB
🖥️

Display & API Support

DirectX support: 12.2 (Quadro RTX 4000) vs 12.2 (Radeon RX 6650M). Vulkan: 1.1 vs 1.4. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 1.

FeatureQuadro RTX 4000Radeon RX 6650M
DirectX
12.2
12.2
Vulkan
1.1
1.4+27%
OpenGL
4.6
4.6
Max Displays
4+300%
1
🎬

Media & Encoding

Hardware encoder: NVENC 7.0 (Quadro RTX 4000) vs VCN 3.0 (Radeon RX 6650M). Decoder: PureVideo HD VP10 vs VCN 3.0. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro RTX 4000) vs MPEG-2,H.264,HEVC,VP9 (Radeon RX 6650M).

FeatureQuadro RTX 4000Radeon RX 6650M
Encoder
NVENC 7.0
VCN 3.0
Decoder
PureVideo HD VP10
VCN 3.0
Codecs
MPEG-2,H.264,HEVC,VP9
MPEG-2,H.264,HEVC,VP9
🔌

Power & Dimensions

The Quadro RTX 4000 draws 160W versus the Radeon RX 6650M's 120W — a 28.6% difference. The Radeon RX 6650M is more power-efficient. Recommended PSU: 500W (Quadro RTX 4000) vs 650W (Radeon RX 6650M). Power connectors: PCIe-powered vs Mobile. Card length: 241mm vs 0mm, occupying 2 vs 0 slots. Typical load temperature: 80°C vs 80°C.

FeatureQuadro RTX 4000Radeon RX 6650M
TDP
160W
120W-25%
Recommended PSU
500W-23%
650W
Power Connector
PCIe-powered
Mobile
Length
241mm
0mm
Height
111mm
0mm
Slots
2
0-100%
Temp (Load)
80°C
80°C
Perf/Watt
93.3
126.4+35%
💰

Value Analysis

The Radeon RX 6650M is the newer GPU (2022 vs 2018).

FeatureQuadro RTX 4000Radeon RX 6650M
MSRP
$899
Codename
TU104
Navi 23
Release
November 13 2018
January 4 2022
Ranking
#154
#148