G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Quadro RTX 4000

2018

Why buy it

✅Access to a newer frame-generation stack with DLSS 3.5 + Frame Generation (2023).

Trade-offs

❌Lower average FPS than Radeon PRO W6600 across 50 tracked games in our benchmark data.
❌Weaker long-term outlook: Radeon PRO W6600 is the safer future-proof pick thanks to newer hardware and better gaming feature support.
❌
38.5% HIGHER MSRP
$899 MSRPvs$649 MSRP
❌Lower G3D Mark per dollar, at 16.6 vs 23.0 G3D/$ ($899 MSRP vs $649 MSRP).
❌60% higher power demand at 160W vs 100W.

Radeon PRO W6600

2021

Why buy it

✅5.9% more average FPS across 50 tracked games in our benchmark data.
✅Costs $250 less on MSRP ($649 MSRP vs $899 MSRP).
✅Delivers 38.6% more G3D Mark for each dollar spent, at 23.0 vs 16.6 G3D/$ ($649 MSRP vs $899 MSRP).
✅More future proof: RDNA 2.0 on 7nm with a newer platform for upcoming games.
✅Draws 100W instead of 160W, a 60W reduction.

Trade-offs

❌No equivalent frame-generation stack like DLSS 3.5 + Frame Generation (2023).

Quadro RTX 4000

2018

Radeon PRO W6600

2021

Why buy it

✅Access to a newer frame-generation stack with DLSS 3.5 + Frame Generation (2023).

Why buy it

✅5.9% more average FPS across 50 tracked games in our benchmark data.
✅Costs $250 less on MSRP ($649 MSRP vs $899 MSRP).
✅Delivers 38.6% more G3D Mark for each dollar spent, at 23.0 vs 16.6 G3D/$ ($649 MSRP vs $899 MSRP).
✅More future proof: RDNA 2.0 on 7nm with a newer platform for upcoming games.
✅Draws 100W instead of 160W, a 60W reduction.

Trade-offs

❌Lower average FPS than Radeon PRO W6600 across 50 tracked games in our benchmark data.
❌Weaker long-term outlook: Radeon PRO W6600 is the safer future-proof pick thanks to newer hardware and better gaming feature support.
❌
38.5% HIGHER MSRP
$899 MSRPvs$649 MSRP
❌Lower G3D Mark per dollar, at 16.6 vs 23.0 G3D/$ ($899 MSRP vs $649 MSRP).
❌60% higher power demand at 160W vs 100W.

Trade-offs

❌No equivalent frame-generation stack like DLSS 3.5 + Frame Generation (2023).

Quick Answers

So, is Radeon PRO W6600 better than Quadro RTX 4000?

Yes, but this is not really about a huge raw performance gap. Radeon PRO W6600 averages 5.9% more FPS across 50 tracked games in our benchmark data. The broader synthetic picture is also very close at 14,925 vs 14,932 in G3D Mark. The bigger reason to prefer Radeon PRO W6600 is the overall package: you are getting a newer generation, FSR upscaling, plus much lower power draw (100W vs 160W).

Which one is more future-proof for 2026 and beyond?

Radeon PRO W6600 is the more future-proof choice for 2026 and beyond. You are getting a newer 2021 generation instead of 2018, better upscaling support with FSR Upscaling / FSR 4 (2025) instead of DLSS 3.5 Super Resolution (2023), and a 7nm process instead of 12nm. That broader feature stack should age better as more games lean on modern upscaling and frame-generation support.

Which one is the smarter buy today, not just the cheaper card?

Radeon PRO W6600 can still make sense if you find it at the right price, especially around $649 MSRP. Radeon PRO W6600 is still the smarter buy for most people, though, because the raw performance is close while the overall package is cleaner. Radeon PRO W6600 is about $250 cheaper on MSRP at $649 MSRP versus $899 MSRP, and you are getting 5.9% more estimated average FPS across 50 tracked games in our benchmark data and 0.0% higher G3D Mark. Moving to $649 MSRP gets you newer hardware, lower power draw (100W vs 160W), and FSR upscaling.

Is Quadro RTX 4000 still worth buying for gaming in 2026?

Yes. Quadro RTX 4000 is still a strong gaming card in 2026: it is very strong for 1080p, good for 1440p, and more limited at 4K. Price is really the swing factor here. If you find it at or below $899 MSRP, it remains a very sensible buy. Radeon PRO W6600 is still the safer recommendation for most fresh builds because it offers a cleaner overall package with newer hardware and FSR upscaling.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Quadro RTX 4000 Benchmark Check

Radeon PRO W6600 Benchmark Check

Path of Exile 2

Preset	Quadro RTX 4000	Radeon PRO W6600
1080p
low	129 FPS	172 FPS
medium	111 FPS	151 FPS
high	92 FPS	134 FPS
ultra	63 FPS	113 FPS
1440p
low	105 FPS	140 FPS
medium	87 FPS	114 FPS
high	67 FPS	101 FPS
ultra	46 FPS	91 FPS
4K
low	46 FPS	84 FPS
medium	40 FPS	71 FPS
high	28 FPS	59 FPS
ultra	24 FPS	51 FPS

Open Quadro RTX 4000 Open Radeon PRO W6600

Path of Exile 2

Path of Exile 2

Counter-Strike 2

Preset	Quadro RTX 4000	Radeon PRO W6600
1080p
low	270 FPS	387 FPS
medium	225 FPS	313 FPS
high	185 FPS	239 FPS
ultra	156 FPS	185 FPS
1440p
low	203 FPS	231 FPS
medium	168 FPS	191 FPS
high	136 FPS	150 FPS
ultra	109 FPS	120 FPS
4K
low	117 FPS	113 FPS
medium	100 FPS	93 FPS
high	80 FPS	78 FPS
ultra	58 FPS	60 FPS

Open Quadro RTX 4000 Open Radeon PRO W6600

Counter-Strike 2

Counter-Strike 2

League of Legends

Preset	Quadro RTX 4000	Radeon PRO W6600
1080p
low	672 FPS	666 FPS
medium	537 FPS	529 FPS
high	448 FPS	445 FPS
ultra	336 FPS	336 FPS
1440p
low	504 FPS	495 FPS
medium	403 FPS	403 FPS
high	336 FPS	336 FPS
ultra	252 FPS	252 FPS
4K
low	336 FPS	336 FPS
medium	269 FPS	269 FPS
high	224 FPS	224 FPS
ultra	168 FPS	168 FPS

Open Quadro RTX 4000 Open Radeon PRO W6600

League of Legends

League of Legends

Valorant

Preset	Quadro RTX 4000	Radeon PRO W6600
1080p
low	248 FPS	623 FPS
medium	215 FPS	518 FPS
high	172 FPS	448 FPS
ultra	145 FPS	336 FPS
1440p
low	190 FPS	472 FPS
medium	168 FPS	387 FPS
high	132 FPS	325 FPS
ultra	108 FPS	252 FPS
4K
low	113 FPS	298 FPS
medium	95 FPS	268 FPS
high	77 FPS	224 FPS
ultra	58 FPS	168 FPS

Open Quadro RTX 4000 Open Radeon PRO W6600

Valorant

Valorant

Check FPS for your specific build

Technical Specifications

Side-by-side comparison of Quadro RTX 4000 and Radeon PRO W6600

Quadro RTX 4000

The Quadro RTX 4000 is manufactured by NVIDIA. It was released in November 13 2018. It features the Turing architecture. The core clock ranges from 1005 MHz to 1545 MHz. It has 2304 shading units. The thermal design power (TDP) is 160W. Manufactured using 12 nm process technology. It features 36 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 14,925 points. Launch price was $899.

Radeon PRO W6600

The Radeon PRO W6600 is manufactured by AMD. It was released in June 8 2021. It features the RDNA 2.0 architecture. The core clock ranges from 2331 MHz to 2903 MHz. It has 1792 shading units. The thermal design power (TDP) is 100W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 14,932 points. Launch price was $649.

⚡

Graphics Performance

The Quadro RTX 4000 scores 14,925 and the Radeon PRO W6600 reaches 14,932 in the G3D Mark benchmark — just a 0% difference, making them near-identical in rasterization performance. The Quadro RTX 4000 is built on Turing while the Radeon PRO W6600 uses RDNA 2.0, both on 12 nm vs 7 nm. Shader units: 2,304 (Quadro RTX 4000) vs 1,792 (Radeon PRO W6600). Raw compute: 7.119 TFLOPS (Quadro RTX 4000) vs 10.4 TFLOPS (Radeon PRO W6600). Boost clocks: 1545 MHz vs 2903 MHz. Ray tracing: 36 RT cores (Quadro RTX 4000) vs 28 (Radeon PRO W6600) with 288 Tensor cores.

Feature	Quadro RTX 4000	Radeon PRO W6600
G3D Mark Score	14,925	14,932
Architecture	Turing	RDNA 2.0
Process Node	12 nm	7 nm
Shading Units	2304+29%	1792
Compute (TFLOPS)	7.119 TFLOPS	10.4 TFLOPS+46%
Boost Clock	1545 MHz	2903 MHz+88%
ROPs	64	64
TMUs	144+29%	112
L1 Cache	2.3 MB+360%	0.5 MB
L2 Cache	4 MB+100%	2 MB
Ray Tracing Cores	36+29%	28

✨

Advanced Features (DLSS/FSR)

A critical advantage for the Quadro RTX 4000 is support for DLSS 3.5 + Frame Generation. This allows it to generate entire frames using AI/Algorithms, essentially doubling the frame rate in CPU-bound scenarios or heavy ray-tracing titles. The Radeon PRO W6600 lacks specific hardware/driver support for this native frame generation tier.The Quadro RTX 4000 gives access to NVIDIA DLSS (Deep Learning Super Sampling), widely regarding as the superior upscaling method for image quality. The Radeon PRO W6600 relies on FSR (FidelityFX Super Resolution), which is capable but generally slightly noisier than DLSS in motion.

Feature	Quadro RTX 4000	Radeon PRO W6600
Upscaling Tech	DLSS 3.5 Super Resolution	FSR Upscaling / FSR 4
Frame Generation	DLSS 3.5 + Frame Generation	Not Supported
Ray Reconstruction	Yes (DLSS 3.5)	No
Low Latency	NVIDIA Reflex	AMD Anti-Lag

💾

Video Memory (VRAM)

Both cards feature 8 GB of GDDR6. Memory bandwidth: 448 GB/s (Quadro RTX 4000) vs 224 GB/s (Radeon PRO W6600) — a 100% advantage for the Quadro RTX 4000. Bus width: 256-bit vs 256-bit. L2 Cache: 4 MB (Quadro RTX 4000) vs 2 MB (Radeon PRO W6600) — the Quadro RTX 4000 has significantly larger on-die cache to reduce VRAM reliance.

Feature	Quadro RTX 4000	Radeon PRO W6600
VRAM Capacity	8 GB	8 GB
Memory Type	GDDR6	GDDR6
Memory Bandwidth	448 GB/s+100%	224 GB/s
Bus Width	256-bit	256-bit
L2 Cache	4 MB+100%	2 MB

🖥️

Display & API Support

DirectX support: 12.2 (Quadro RTX 4000) vs 12.2 (Radeon PRO W6600). Vulkan: 1.1 vs 1.4. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 3.

Feature	Quadro RTX 4000	Radeon PRO W6600
DirectX	12.2	12.2
Vulkan	1.1	1.4+27%
OpenGL	4.6	4.6
Max Displays	4+33%	3

🎬

Media & Encoding

Hardware encoder: NVENC 7.0 (Quadro RTX 4000) vs VCN 3.0 (Radeon PRO W6600). Decoder: PureVideo HD VP10 vs VCN 3.0. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro RTX 4000) vs MPEG-2,H.264,HEVC,VP9 (Radeon PRO W6600).

Feature	Quadro RTX 4000	Radeon PRO W6600
Encoder	NVENC 7.0	VCN 3.0
Decoder	PureVideo HD VP10	VCN 3.0
Codecs	MPEG-2,H.264,HEVC,VP9	MPEG-2,H.264,HEVC,VP9

🔌

Power & Dimensions

The Quadro RTX 4000 draws 160W versus the Radeon PRO W6600's 100W — a 46.2% difference. The Radeon PRO W6600 is more power-efficient. Recommended PSU: 500W (Quadro RTX 4000) vs 500W (Radeon PRO W6600). Power connectors: PCIe-powered vs PCIe-powered. Card length: 241mm vs 190mm, occupying 2 vs 2 slots. Typical load temperature: 80°C vs 75°C.

Feature	Quadro RTX 4000	Radeon PRO W6600
TDP	160W	100W-38%
Recommended PSU	500W	500W
Power Connector	PCIe-powered	PCIe-powered
Length	241mm	190mm
Height	111mm	111mm
Slots	2	2
Temp (Load)	80°C	75°C-6%
Perf/Watt	93.3	149.3+60%

💰

Value Analysis

The Quadro RTX 4000 launched at $899 MSRP, while the Radeon PRO W6600 launched at $649. The Radeon PRO W6600 costs 27.8% less ($250 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 16.6 (Quadro RTX 4000) vs 23.0 (Radeon PRO W6600) — the Radeon PRO W6600 offers 38.6% better value. The Radeon PRO W6600 is the newer GPU (2021 vs 2018).