Ryzen Threadripper PRO 3995WX vs Xeon 6780E

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

Ryzen Threadripper PRO 3995WX

2020

Why buy it

✅+137% larger total L3 cache (256 MB vs 108 MB).
✅Costs $5,861 less on MSRP ($5,489 MSRP vs $11,350 MSRP).
✅Delivers 98.4% more PassMark for each dollar spent, at 15.2 vs 7.6 PassMark/$ ($5,489 MSRP vs $11,350 MSRP).
✅Draws 280W instead of 330W, a 50W reduction.
✅45.5% more PCIe lanes (128 vs 88) for storage and expansion-heavy builds.

Trade-offs

❌Worse for gaming: lower average FPS than Xeon 6780E across 4 shared CPU benchmark tests.
❌Lower PassMark (83,235 vs 86,734).
❌Older platform position on sWRX8 with DDR4, while Xeon 6780E moves to LGA4710 and DDR5.

Xeon 6780E

2024

Why buy it

✅Better for gaming: +5.6% higher average FPS across 4 shared CPU benchmark tests.
✅Newer platform on LGA4710 with DDR5 support instead of sWRX8 and DDR4.

Trade-offs

❌Smaller total L3 cache (108 MB vs 256 MB).
❌Lower PassMark per dollar, at 7.6 vs 15.2 PassMark/$ ($11,350 MSRP vs $5,489 MSRP).
❌17.9% higher power demand at 330W vs 280W.

Ryzen Threadripper PRO 3995WX

2020

Xeon 6780E

2024

Why buy it

✅+137% larger total L3 cache (256 MB vs 108 MB).
✅Costs $5,861 less on MSRP ($5,489 MSRP vs $11,350 MSRP).
✅Delivers 98.4% more PassMark for each dollar spent, at 15.2 vs 7.6 PassMark/$ ($5,489 MSRP vs $11,350 MSRP).
✅Draws 280W instead of 330W, a 50W reduction.
✅45.5% more PCIe lanes (128 vs 88) for storage and expansion-heavy builds.

Why buy it

✅Better for gaming: +5.6% higher average FPS across 4 shared CPU benchmark tests.
✅Newer platform on LGA4710 with DDR5 support instead of sWRX8 and DDR4.

Trade-offs

❌Worse for gaming: lower average FPS than Xeon 6780E across 4 shared CPU benchmark tests.
❌Lower PassMark (83,235 vs 86,734).
❌Older platform position on sWRX8 with DDR4, while Xeon 6780E moves to LGA4710 and DDR5.

Trade-offs

❌Smaller total L3 cache (108 MB vs 256 MB).
❌Lower PassMark per dollar, at 7.6 vs 15.2 PassMark/$ ($11,350 MSRP vs $5,489 MSRP).
❌17.9% higher power demand at 330W vs 280W.

Quick Answers

So, is Xeon 6780E better than Ryzen Threadripper PRO 3995WX?

Yes. Xeon 6780E is the better overall CPU here. You are getting a 5.6% average FPS lead across 4 shared CPU game tests in our data, 4.2% better PassMark, and the stronger long-term platform, which makes it the stronger all-around choice.

Which one is better for gaming?

If gaming is the priority, Xeon 6780E is the better pick here. According to our tests, it delivers 5.6% more average FPS across 4 shared CPU game tests.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, Xeon 6780E is the better fit. You are getting 4.2% better PassMark, backed by 144 cores and 144 threads.

Which one is the smarter buy today, not just the cheaper CPU?

Xeon 6780E is still the faster CPU overall, but Ryzen Threadripper PRO 3995WX makes more sense if price matters more than absolute performance. Xeon 6780E is 106.8% more expensive on MSRP at $11,350 MSRP versus $5,489 MSRP, and it gives you a 5.6% average FPS lead across 4 shared CPU game tests in our data. Ryzen Threadripper PRO 3995WX is also 98.4% better value on MSRP (15.2 vs 7.6 PassMark/$), which is why it is easier to justify for price-conscious builds on paper.

Which one is more future-proof for 2026 and beyond?

Xeon 6780E is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2024 vs 2020), a healthier platform with LGA4710 and DDR5 instead of sWRX8, and more multi-core headroom with 144 cores / 144 threads instead of 64/128. That should give you a better long-term upgrade path for motherboard, RAM, and future CPU swaps.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Ryzen Threadripper PRO 3995WX Benchmark Check

Xeon 6780E Benchmark Check

Path of Exile 2

Preset	Ryzen Threadripper PRO 3995WX	Xeon 6780E
1080p
low	173 FPS	189 FPS
medium	142 FPS	152 FPS
high	121 FPS	121 FPS
ultra	97 FPS	95 FPS
1440p
low	152 FPS	153 FPS
medium	122 FPS	119 FPS
high	97 FPS	91 FPS
ultra	78 FPS	73 FPS
4K
low	71 FPS	71 FPS
medium	61 FPS	59 FPS
high	48 FPS	46 FPS
ultra	40 FPS	38 FPS

Open Ryzen Threadripper PRO 3995WX Open Xeon 6780E

Path of Exile 2

Path of Exile 2

Counter-Strike 2

Preset	Ryzen Threadripper PRO 3995WX	Xeon 6780E
1080p
low	571 FPS	244 FPS
medium	495 FPS	216 FPS
high	380 FPS	178 FPS
ultra	325 FPS	142 FPS
1440p
low	480 FPS	200 FPS
medium	423 FPS	181 FPS
high	336 FPS	154 FPS
ultra	272 FPS	120 FPS
4K
low	301 FPS	124 FPS
medium	269 FPS	115 FPS
high	230 FPS	100 FPS
ultra	201 FPS	81 FPS

Open Ryzen Threadripper PRO 3995WX Open Xeon 6780E

Counter-Strike 2

Counter-Strike 2

League of Legends

Preset	Ryzen Threadripper PRO 3995WX	Xeon 6780E
1080p
low	660 FPS	934 FPS
medium	546 FPS	831 FPS
high	481 FPS	779 FPS
ultra	412 FPS	693 FPS
1440p
low	555 FPS	746 FPS
medium	465 FPS	655 FPS
high	412 FPS	614 FPS
ultra	354 FPS	546 FPS
4K
low	406 FPS	479 FPS
medium	323 FPS	378 FPS
high	285 FPS	334 FPS
ultra	227 FPS	272 FPS

Open Ryzen Threadripper PRO 3995WX Open Xeon 6780E

League of Legends

League of Legends

Valorant

Preset	Ryzen Threadripper PRO 3995WX	Xeon 6780E
1080p
low	909 FPS	897 FPS
medium	818 FPS	807 FPS
high	695 FPS	691 FPS
ultra	604 FPS	588 FPS
1440p
low	739 FPS	697 FPS
medium	643 FPS	606 FPS
high	545 FPS	517 FPS
ultra	463 FPS	436 FPS
4K
low	514 FPS	500 FPS
medium	461 FPS	446 FPS
high	407 FPS	390 FPS
ultra	346 FPS	334 FPS

Open Ryzen Threadripper PRO 3995WX Open Xeon 6780E

Valorant

Valorant

Check FPS for your specific build

Technical Specifications

Side-by-side comparison of Ryzen Threadripper PRO 3995WX and Xeon 6780E

Ryzen Threadripper PRO 3995WX

The Ryzen Threadripper PRO 3995WX is manufactured by AMD. It was released in 14 July 2020 (5 years ago). It is based on the Matisse (2019−2020) architecture. It features 64 cores and 128 threads. Base frequency is 2.7 GHz, with boost up to 4.2 GHz. L3 cache: 256 MB. L2 cache: 512K (per core). Built on 7 nm, 12 nm process technology. Socket: sWRX8. Thermal design power (TDP): 280 Watt. Memory support: DDR4-3200. Passmark benchmark score: 83,235 points. Launch price was $5,500.

Xeon 6780E

The Xeon 6780E is manufactured by Intel. It was released in 3 June 2024 (1 year ago). It is based on the Sierra Forest (2024) architecture. It features 144 cores and 144 threads. Base frequency is 2.2 GHz, with boost up to 3 GHz. L3 cache: 108 MB (total). L2 cache: 4 MB (per module). Built on Intel 3 nm process technology. Socket: LGA4710. Thermal design power (TDP): 330 Watt. Memory support: DDR5-6400. Passmark benchmark score: 86,734 points. Launch price was $11,350.

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Processing Power

The Ryzen Threadripper PRO 3995WX packs 64 cores / 128 threads, while the Xeon 6780E offers 144 cores / 144 threads — the Xeon 6780E has 80 more cores. Boost clocks reach 4.2 GHz on the Ryzen Threadripper PRO 3995WX versus 3 GHz on the Xeon 6780E — a 33.3% clock advantage for the Ryzen Threadripper PRO 3995WX (base: 2.7 GHz vs 2.2 GHz). The Ryzen Threadripper PRO 3995WX uses the Matisse (2019−2020) architecture (7 nm, 12 nm), while the Xeon 6780E uses Sierra Forest (2024) (Intel 3 nm). In PassMark, the Ryzen Threadripper PRO 3995WX scores 83,235 against the Xeon 6780E's 86,734 — a 4.1% lead for the Xeon 6780E. L3 cache: 256 MB on the Ryzen Threadripper PRO 3995WX vs 108 MB (total) on the Xeon 6780E.

Feature	Ryzen Threadripper PRO 3995WX	Xeon 6780E
Cores / Threads	64 / 128	144 / 144+125%
Boost Clock	4.2 GHz+40%	3 GHz
Base Clock	2.7 GHz+23%	2.2 GHz
L3 Cache	256 MB+137%	108 MB (total)
L2 Cache	512K (per core)	4 MB (per module)+700%
Process	7 nm, 12 nm	Intel 3 nm-57%
Architecture	Matisse (2019−2020)	Sierra Forest (2024)
PassMark	83,235	86,734+4%
Cinebench R23 Multi	64,355	—
Geekbench 6 Single	1,266	—
Geekbench 6 Multi	20,256	—

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Memory & Platform

The Ryzen Threadripper PRO 3995WX uses the sWRX8 socket (PCIe 4.0), while the Xeon 6780E uses LGA4710 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches DDR4-3200 on the Ryzen Threadripper PRO 3995WX versus DDR5-6400 on the Xeon 6780E — the Xeon 6780E supports 22.2% faster memory, which can translate to measurable gains in memory-sensitive workloads. The Ryzen Threadripper PRO 3995WX supports up to 2048 GB of RAM compared to 4 TB — 199.2% more capacity for professional workloads. Both feature 8-channel memory with ECC support. PCIe lanes: 128 (Ryzen Threadripper PRO 3995WX) vs 88 (Xeon 6780E) — the Ryzen Threadripper PRO 3995WX offers 40 more lanes for additional GPUs or NVMe drives.

Feature	Ryzen Threadripper PRO 3995WX	Xeon 6780E
Socket	sWRX8	LGA4710
PCIe Generation	PCIe 4.0	PCIe 4.0
Max RAM Speed	DDR4-3200	DDR5-6400+25%
Max RAM Capacity	2048 GB	4 TB+100%
RAM Channels	8	8
ECC Support	Yes	Yes
PCIe Lanes	128+45%	88

🔧

Advanced Features

Virtualization support: true (Ryzen Threadripper PRO 3995WX) vs VT-x, VT-d, VT-x EPT (Xeon 6780E). Primary use case: Xeon 6780E targets Cloud Native Compute. Direct competitor: Ryzen Threadripper PRO 3995WX rivals Xeon Platinum 8280; Xeon 6780E rivals EPYC 9754.

Feature	Ryzen Threadripper PRO 3995WX	Xeon 6780E
Integrated GPU	No	No
IGPU Model	None	—
Unlocked	Yes	—
AVX-512	No	—
Virtualization	true	VT-x, VT-d, VT-x EPT
Target Use	—	Cloud Native Compute

💰

Value Analysis

The Ryzen Threadripper PRO 3995WX launched at $5489 MSRP, while the Xeon 6780E debuted at $11350. On MSRP ($5489 vs $11350), the Ryzen Threadripper PRO 3995WX is $5861 cheaper. In terms of value on MSRP (PassMark points per dollar), the Ryzen Threadripper PRO 3995WX delivers 15.2 pts/$ vs 7.6 pts/$ for the Xeon 6780E — making the Ryzen Threadripper PRO 3995WX the 66% better value option.