Ryzen 5 PRO 4650GE vs Xeon E5-4660 v4

AMD

Ryzen 5 PRO 4650GE

6 Cores12 Thrd35 WWMax: 4.2 GHz2020

Popular choices:

VS
Intel

Xeon E5-4660 v4

16 Cores32 Thrd120 WWMax: 3 GHz2016

Popular choices:

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

Ryzen 5 PRO 4650GE

2020

Why buy it

  • Better for gaming: +6.0% higher average FPS across 4 shared CPU benchmark tests.
  • Draws 35W instead of 120W, a 85W reduction.

Trade-offs

  • Lower PassMark (15,316 vs 15,375).
  • Smaller total L3 cache (8 MB vs 40 MB).
  • Less compelling for workstation-style loads than Xeon E5-4660 v4, which brings 16 cores / 32 threads.
  • Launch MSRP is still $209 MSRP, while Xeon E5-4660 v4 mostly shows up through inconsistent older-market listings.

Xeon E5-4660 v4

2016

Why buy it

  • +0.4% higher PassMark.
  • +400% larger total L3 cache (40 MB vs 8 MB).
  • Better for workstations and heavier parallel workloads: 16 cores / 32 threads.

Trade-offs

  • Worse for gaming: lower average FPS than Ryzen 5 PRO 4650GE across 4 shared CPU benchmark tests.
  • 242.9% higher power demand at 120W vs 35W.

Quick Answers

So, is Ryzen 5 PRO 4650GE better than Xeon E5-4660 v4?
Not in a simple one-size-fits-all way. Xeon E5-4660 v4 makes more sense for workstation-style multi-core throughput, while Ryzen 5 PRO 4650GE is the better mainstream desktop choice for gaming, platform cost, and day-to-day practicality.
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, Xeon E5-4660 v4 is the better fit. You are getting 0.4% better PassMark, backed by 16 cores and 32 threads. It also carries the larger cache pool with 400% larger total L3 cache (40 MB vs 8 MB).
Which one is the smarter buy today, not just the cheaper CPU?
Ryzen 5 PRO 4650GE is the smarter buy today. Ryzen 5 PRO 4650GE is at an unclear MSRP at $209 MSRP versus unclear MSRP, and it gives you a 6.0% average FPS lead across 4 shared CPU game tests in our data. The trade-off is that Xeon E5-4660 v4 is still stronger for heavier multi-core work with 0.4% better PassMark. It is also 100.0% better value on MSRP (73.3 vs 0.0 PassMark/$), so the better CPU is not just faster, it is also the cleaner value play on paper.
Which one is more future-proof for 2026 and beyond?
Ryzen 5 PRO 4650GE is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2020 vs 2016). That makes it the safer long-term pick.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Path of Exile 2

Path of Exile 2

PresetRyzen 5 PRO 4650GEXeon E5-4660 v4
1080p
low177 FPS176 FPS
medium143 FPS152 FPS
high114 FPS119 FPS
ultra90 FPS95 FPS
1440p
low152 FPS147 FPS
medium121 FPS123 FPS
high94 FPS94 FPS
ultra74 FPS76 FPS
4K
low69 FPS68 FPS
medium59 FPS61 FPS
high46 FPS47 FPS
ultra37 FPS38 FPS
Counter-Strike 2

Counter-Strike 2

PresetRyzen 5 PRO 4650GEXeon E5-4660 v4
1080p
low298 FPS210 FPS
medium257 FPS191 FPS
high229 FPS162 FPS
ultra198 FPS131 FPS
1440p
low261 FPS180 FPS
medium229 FPS164 FPS
high208 FPS142 FPS
ultra179 FPS110 FPS
4K
low225 FPS114 FPS
medium202 FPS105 FPS
high182 FPS92 FPS
ultra156 FPS73 FPS
League of Legends

League of Legends

PresetRyzen 5 PRO 4650GEXeon E5-4660 v4
1080p
low383 FPS384 FPS
medium383 FPS384 FPS
high383 FPS384 FPS
ultra383 FPS384 FPS
1440p
low383 FPS384 FPS
medium383 FPS384 FPS
high383 FPS384 FPS
ultra362 FPS384 FPS
4K
low383 FPS384 FPS
medium332 FPS363 FPS
high286 FPS328 FPS
ultra227 FPS274 FPS
Valorant

Valorant

PresetRyzen 5 PRO 4650GEXeon E5-4660 v4
1080p
low383 FPS384 FPS
medium383 FPS384 FPS
high383 FPS384 FPS
ultra383 FPS384 FPS
1440p
low383 FPS384 FPS
medium383 FPS384 FPS
high383 FPS384 FPS
ultra383 FPS384 FPS
4K
low383 FPS384 FPS
medium383 FPS384 FPS
high378 FPS384 FPS
ultra316 FPS353 FPS

Technical Specifications

Side-by-side comparison of Ryzen 5 PRO 4650GE and Xeon E5-4660 v4

AMD

Ryzen 5 PRO 4650GE

The Ryzen 5 PRO 4650GE is manufactured by AMD. It was released in 21 July 2020 (5 years ago). It is based on the Renoir (2020−2023) architecture. It features 6 cores and 12 threads. Base frequency is 3.3 GHz, with boost up to 4.2 GHz. L3 cache: 8 MB (total). L2 cache: 512 kB (per core). Built on 7 nm process technology. Socket: AM4. Thermal design power (TDP): 35 Watt. Memory support: DDR4-3200. Passmark benchmark score: 15,316 points. Launch price was $299.

Intel

Xeon E5-4660 v4

The Xeon E5-4660 v4 is manufactured by Intel. It was released in 20 June 2016 (9 years ago). It is based on the Broadwell (2015−2019) architecture. It features 16 cores and 32 threads. Base frequency is 2.2 GHz, with boost up to 3 GHz. L3 cache: 40 MB. L2 cache: 4 MB. Built on 14 nm process technology. Socket: LGA2011. Thermal design power (TDP): 120 Watt. Memory support: DDR4. Passmark benchmark score: 15,375 points. Launch price was $4,727.

Processing Power

The Ryzen 5 PRO 4650GE packs 6 cores / 12 threads, while the Xeon E5-4660 v4 offers 16 cores / 32 threads — the Xeon E5-4660 v4 has 10 more cores. Boost clocks reach 4.2 GHz on the Ryzen 5 PRO 4650GE versus 3 GHz on the Xeon E5-4660 v4 — a 33.3% clock advantage for the Ryzen 5 PRO 4650GE (base: 3.3 GHz vs 2.2 GHz). The Ryzen 5 PRO 4650GE uses the Renoir (2020−2023) architecture (7 nm), while the Xeon E5-4660 v4 uses Broadwell (2015−2019) (14 nm). In PassMark, the Ryzen 5 PRO 4650GE scores 15,316 against the Xeon E5-4660 v4's 15,375 — a 0.4% lead for the Xeon E5-4660 v4. L3 cache: 8 MB (total) on the Ryzen 5 PRO 4650GE vs 40 MB on the Xeon E5-4660 v4.

FeatureRyzen 5 PRO 4650GEXeon E5-4660 v4
Cores / Threads
6 / 12
16 / 32+167%
Boost Clock
4.2 GHz+40%
3 GHz
Base Clock
3.3 GHz+50%
2.2 GHz
L3 Cache
8 MB (total)
40 MB+400%
L2 Cache
512 kB (per core)
4 MB+700%
Process
7 nm-50%
14 nm
Architecture
Renoir (2020−2023)
Broadwell (2015−2019)
PassMark
15,316
15,375
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Memory & Platform

The Ryzen 5 PRO 4650GE uses the AM4 socket (PCIe 3.0), while the Xeon E5-4660 v4 uses LGA2011 (PCIe 3.0) — making them incompatible on the same motherboard.

FeatureRyzen 5 PRO 4650GEXeon E5-4660 v4
Socket
AM4
LGA2011
PCIe Generation
PCIe 3.0
PCIe 3.0