
Quadro GP100
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Radeon Pro Vega 64X
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Performance Spectrum - GPU
About G3D Mark
G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.
Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook
This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.
Quadro GP100
2016Why buy it
- ✅43.0% more average FPS across 48 tracked games in our benchmark data.
- ✅100+% more VRAM for high-resolution textures and newer games (16 GB vs Unknown).
- ✅Less risky long-term buy than Radeon Pro Vega 64X: it remains the more sensible modern option while Radeon Pro Vega 64X is already legacy-tier future-proofing.
Trade-offs
- ❌Poor future-proofing: 2016-era hardware with 16 GB of VRAM is already a legacy-tier option for modern games.
- ❌218.2% HIGHER MSRP$7,000 MSRPvs$2,200 MSRP
- ❌Lower G3D Mark per dollar, at 2.0 vs 6.1 G3D/$ ($7,000 MSRP vs $2,200 MSRP).
Radeon Pro Vega 64X
2019Why buy it
- ✅Costs $4,800 less on MSRP ($2,200 MSRP vs $7,000 MSRP).
- ✅Delivers 210.3% more G3D Mark for each dollar spent, at 6.1 vs 2.0 G3D/$ ($2,200 MSRP vs $7,000 MSRP).
- ✅More future proof: GCN 5.0 (2017−2020) on 14nm with a newer platform for upcoming games.
Trade-offs
- ❌Lower average FPS than Quadro GP100 across 48 tracked games in our benchmark data.
- ❌Less VRAM, with Unknown vs 16 GB for high-resolution textures and newer games.
- ❌Poor future-proofing: 2019-era hardware with Unknown of VRAM is already a legacy-tier option for modern games.
Quadro GP100
2016Radeon Pro Vega 64X
2019Why buy it
- ✅43.0% more average FPS across 48 tracked games in our benchmark data.
- ✅100+% more VRAM for high-resolution textures and newer games (16 GB vs Unknown).
- ✅Less risky long-term buy than Radeon Pro Vega 64X: it remains the more sensible modern option while Radeon Pro Vega 64X is already legacy-tier future-proofing.
Why buy it
- ✅Costs $4,800 less on MSRP ($2,200 MSRP vs $7,000 MSRP).
- ✅Delivers 210.3% more G3D Mark for each dollar spent, at 6.1 vs 2.0 G3D/$ ($2,200 MSRP vs $7,000 MSRP).
- ✅More future proof: GCN 5.0 (2017−2020) on 14nm with a newer platform for upcoming games.
Trade-offs
- ❌Poor future-proofing: 2016-era hardware with 16 GB of VRAM is already a legacy-tier option for modern games.
- ❌218.2% HIGHER MSRP$7,000 MSRPvs$2,200 MSRP
- ❌Lower G3D Mark per dollar, at 2.0 vs 6.1 G3D/$ ($7,000 MSRP vs $2,200 MSRP).
Trade-offs
- ❌Lower average FPS than Quadro GP100 across 48 tracked games in our benchmark data.
- ❌Less VRAM, with Unknown vs 16 GB for high-resolution textures and newer games.
- ❌Poor future-proofing: 2019-era hardware with Unknown of VRAM is already a legacy-tier option for modern games.
Quick Answers
So, is Quadro GP100 better than Radeon Pro Vega 64X?
Which one is more future-proof for 2026 and beyond?
Which one is the smarter buy today, not just the cheaper card?
When does Radeon Pro Vega 64X make more sense than Quadro GP100?
Games Benchmarks
Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.
Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2
| Preset | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| 1080p | ||
| low | 190 FPS | 108 FPS |
| medium | 177 FPS | 98 FPS |
| high | 152 FPS | 83 FPS |
| ultra | 138 FPS | 69 FPS |
| 1440p | ||
| low | 177 FPS | 96 FPS |
| medium | 149 FPS | 82 FPS |
| high | 118 FPS | 66 FPS |
| ultra | 108 FPS | 56 FPS |
| 4K | ||
| low | 109 FPS | 48 FPS |
| medium | 91 FPS | 43 FPS |
| high | 67 FPS | 33 FPS |
| ultra | 61 FPS | 29 FPS |

Counter-Strike 2
| Preset | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| 1080p | ||
| low | 313 FPS | 301 FPS |
| medium | 274 FPS | 262 FPS |
| high | 207 FPS | 203 FPS |
| ultra | 171 FPS | 164 FPS |
| 1440p | ||
| low | 212 FPS | 204 FPS |
| medium | 181 FPS | 175 FPS |
| high | 145 FPS | 144 FPS |
| ultra | 118 FPS | 114 FPS |
| 4K | ||
| low | 108 FPS | 100 FPS |
| medium | 91 FPS | 84 FPS |
| high | 75 FPS | 71 FPS |
| ultra | 59 FPS | 56 FPS |

League of Legends
| Preset | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| 1080p | ||
| low | 617 FPS | 526 FPS |
| medium | 494 FPS | 452 FPS |
| high | 411 FPS | 383 FPS |
| ultra | 308 FPS | 301 FPS |
| 1440p | ||
| low | 463 FPS | 413 FPS |
| medium | 370 FPS | 347 FPS |
| high | 308 FPS | 296 FPS |
| ultra | 231 FPS | 226 FPS |
| 4K | ||
| low | 308 FPS | 258 FPS |
| medium | 247 FPS | 214 FPS |
| high | 206 FPS | 173 FPS |
| ultra | 154 FPS | 135 FPS |

Valorant
| Preset | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| 1080p | ||
| low | 455 FPS | 258 FPS |
| medium | 417 FPS | 213 FPS |
| high | 334 FPS | 180 FPS |
| ultra | 286 FPS | 151 FPS |
| 1440p | ||
| low | 365 FPS | 197 FPS |
| medium | 337 FPS | 162 FPS |
| high | 259 FPS | 133 FPS |
| ultra | 218 FPS | 112 FPS |
| 4K | ||
| low | 234 FPS | 118 FPS |
| medium | 218 FPS | 105 FPS |
| high | 177 FPS | 85 FPS |
| ultra | 146 FPS | 70 FPS |
Technical Specifications
Side-by-side comparison of Quadro GP100 and Radeon Pro Vega 64X

Quadro GP100
Quadro GP100
The Quadro GP100 is manufactured by NVIDIA. It was released in October 1 2016. It features the Pascal architecture. The core clock ranges from 1304 MHz to 1442 MHz. It has 3584 shading units. The thermal design power (TDP) is 235W. Manufactured using 16 nm process technology. G3D Mark benchmark score: 13,710 points.

Radeon Pro Vega 64X
Radeon Pro Vega 64X
The Radeon Pro Vega 64X is manufactured by AMD. It was released in March 19 2019. It features the GCN 5.0 architecture. The core clock ranges from 1250 MHz to 1468 MHz. It has 4096 shading units. The thermal design power (TDP) is 250W. Manufactured using 14 nm process technology. G3D Mark benchmark score: 13,369 points.
Graphics Performance
The Quadro GP100 scores 13,710 and the Radeon Pro Vega 64X reaches 13,369 in the G3D Mark benchmark — just a 2.6% difference, making them near-identical in rasterization performance. The Quadro GP100 is built on Pascal while the Radeon Pro Vega 64X uses GCN 5.0, both on 16 nm vs 14 nm. Shader units: 3,584 (Quadro GP100) vs 4,096 (Radeon Pro Vega 64X). Raw compute: 10.34 TFLOPS (Quadro GP100) vs 12.03 TFLOPS (Radeon Pro Vega 64X). Boost clocks: 1442 MHz vs 1468 MHz.
| Feature | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| G3D Mark Score | 13,710+3% | 13,369 |
| Architecture | Pascal | GCN 5.0 |
| Process Node | 16 nm | 14 nm |
| Shading Units | 3584 | 4096+14% |
| Compute (TFLOPS) | 10.34 TFLOPS | 12.03 TFLOPS+16% |
| Boost Clock | 1442 MHz | 1468 MHz+2% |
| ROPs | 96+50% | 64 |
| TMUs | 224 | 256+14% |
| L1 Cache | 1.3 MB+30% | 1 MB |
| L2 Cache | 4 MB | 4 MB |
Advanced Features (DLSS/FSR)
| Feature | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| Upscaling Tech | Upscaling support | FSR Upscaling / FSR 4 |
| Frame Generation | Not Supported | Not Supported |
| Ray Reconstruction | No | No |
| Low Latency | Standard | AMD Anti-Lag |
Video Memory (VRAM)
The Quadro GP100 comes with 16 GB of VRAM, while the Radeon Pro Vega 64X has 0 MB. The Quadro GP100 offers 100+% more capacity, crucial for higher resolutions and texture-heavy games. Bus width: 4096-bit vs 128-bit.
| Feature | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| VRAM Capacity | 16 GB | Shared System RAM |
| Memory Type | HBM2 | GDDR6 |
| Bus Width | 4096-bit+3100% | 128-bit |
| L2 Cache | 4 MB | 4 MB |
Display & API Support
DirectX support: 12 (Quadro GP100) vs 12.1 (Radeon Pro Vega 64X). Vulkan: 1.3 vs 1.1. OpenGL: 4.5 vs 4.6. Maximum simultaneous displays: 4 vs 4.
| Feature | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| DirectX | 12 | 12.1 |
| Vulkan | 1.3+18% | 1.1 |
| OpenGL | 4.5 | 4.6+2% |
| Max Displays | 4 | 4 |
Media & Encoding
Hardware encoder: NVENC 4th gen (Quadro GP100) vs VCE 4.0 (Radeon Pro Vega 64X). Decoder: NVDEC 3rd gen vs UVD 7.0. Supported codecs: H.264,H.265/HEVC,MPEG-2,VC-1,VP8,VP9 (Quadro GP100) vs MPEG-2,H.264,HEVC,VP9 (Radeon Pro Vega 64X).
| Feature | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| Encoder | NVENC 4th gen | VCE 4.0 |
| Decoder | NVDEC 3rd gen | UVD 7.0 |
| Codecs | H.264,H.265/HEVC,MPEG-2,VC-1,VP8,VP9 | MPEG-2,H.264,HEVC,VP9 |
Power & Dimensions
The Quadro GP100 draws 235W versus the Radeon Pro Vega 64X's 250W — a 6.2% difference. The Quadro GP100 is more power-efficient. Recommended PSU: 500W (Quadro GP100) vs 1W (Radeon Pro Vega 64X). Power connectors: PCIe-powered vs Integrated. Card length: 267mm vs 0mm, occupying 2 vs 0 slots. Typical load temperature: 80°C vs 85°C.
| Feature | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| TDP | 235W-6% | 250W |
| Recommended PSU | 500W | 1W-100% |
| Power Connector | PCIe-powered | Integrated |
| Length | 267mm | 0mm |
| Height | 111mm | 0mm |
| Slots | 2 | 0-100% |
| Temp (Load) | 80°C-6% | 85°C |
| Perf/Watt | 58.3+9% | 53.5 |
Value Analysis
The Quadro GP100 launched at $7000 MSRP, while the Radeon Pro Vega 64X launched at $2200. The Radeon Pro Vega 64X costs 68.6% less ($4800 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 2.0 (Quadro GP100) vs 6.1 (Radeon Pro Vega 64X) — the Radeon Pro Vega 64X offers 205% better value. The Radeon Pro Vega 64X is the newer GPU (2019 vs 2016).
| Feature | Quadro GP100 | Radeon Pro Vega 64X |
|---|---|---|
| MSRP | $7000 | $2200-69% |
| Performance per Dollar | 2.0 | 6.1+205% |
| Codename | GP100 | Vega 10 |
| Release | October 1 2016 | March 19 2019 |
| Ranking | #178 | #190 |
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