PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

EPYC 7543

2021

Why buy it

✅Better for gaming: +8.3% higher average FPS across 4 shared CPU benchmark tests.
✅+100% larger total L3 cache (256 MB vs 128 MB).
✅Draws 225W instead of 280W, a 55W reduction.

Trade-offs

❌Lower PassMark per dollar, at 6.1 vs 46.6 PassMark/$ ($10,257 MSRP vs $1,337 MSRP).

Ryzen Threadripper PRO 3975WX

2020

Why buy it

✅Costs $8,920 less on MSRP ($1,337 MSRP vs $10,257 MSRP).
✅Delivers 658.7% more PassMark for each dollar spent, at 46.6 vs 6.1 PassMark/$ ($1,337 MSRP vs $10,257 MSRP).

Trade-offs

❌Worse for gaming: lower average FPS than EPYC 7543 across 4 shared CPU benchmark tests.
❌Lower PassMark (62,261 vs 62,952).
❌Smaller total L3 cache (128 MB vs 256 MB).
❌24.4% higher power demand at 280W vs 225W.

EPYC 7543

2021

Ryzen Threadripper PRO 3975WX

2020

Why buy it

✅Better for gaming: +8.3% higher average FPS across 4 shared CPU benchmark tests.
✅+100% larger total L3 cache (256 MB vs 128 MB).
✅Draws 225W instead of 280W, a 55W reduction.

Why buy it

✅Costs $8,920 less on MSRP ($1,337 MSRP vs $10,257 MSRP).
✅Delivers 658.7% more PassMark for each dollar spent, at 46.6 vs 6.1 PassMark/$ ($1,337 MSRP vs $10,257 MSRP).

Trade-offs

❌Lower PassMark per dollar, at 6.1 vs 46.6 PassMark/$ ($10,257 MSRP vs $1,337 MSRP).

Trade-offs

❌Worse for gaming: lower average FPS than EPYC 7543 across 4 shared CPU benchmark tests.
❌Lower PassMark (62,261 vs 62,952).
❌Smaller total L3 cache (128 MB vs 256 MB).
❌24.4% higher power demand at 280W vs 225W.

Quick Answers

So, is EPYC 7543 better than Ryzen Threadripper PRO 3975WX?

Yes. EPYC 7543 is the better overall CPU here. You are getting a 8.3% average FPS lead across 4 shared CPU game tests in our data, 1.1% better PassMark, and the stronger long-term platform, which makes it the stronger all-around choice.

Which one is better for gaming?

If gaming is the priority, EPYC 7543 is the better pick here. According to our tests, it delivers 8.3% more average FPS across 4 shared CPU game tests.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, EPYC 7543 is the better fit. You are getting 1.1% better PassMark, backed by 32 cores and 64 threads. It also carries the larger cache pool with 100% larger total L3 cache (256 MB vs 128 MB).

Which one is the smarter buy today, not just the cheaper CPU?

EPYC 7543 is still the faster CPU overall, but Ryzen Threadripper PRO 3975WX makes more sense if price matters more than absolute performance. EPYC 7543 is 667.2% more expensive on MSRP at $10,257 MSRP versus $1,337 MSRP, and it gives you a 8.3% average FPS lead across 4 shared CPU game tests in our data. Ryzen Threadripper PRO 3975WX is also 658.7% better value on MSRP (46.6 vs 6.1 PassMark/$), which is why it is easier to justify for price-conscious builds on paper.

Which one is more future-proof for 2026 and beyond?

EPYC 7543 is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2021 vs 2020), 100% larger total L3 cache (256 MB vs 128 MB), and more multi-core headroom with 32 cores / 64 threads instead of 32/64. That extra cache should hold up really well in CPU-limited games and high-refresh builds.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

EPYC 7543 Benchmark Check

Ryzen Threadripper PRO 3975WX Benchmark Check

Path of Exile 2

Preset	EPYC 7543	Ryzen Threadripper PRO 3975WX
1080p
low	198 FPS	183 FPS
medium	161 FPS	149 FPS
high	129 FPS	126 FPS
ultra	100 FPS	98 FPS
1440p
low	161 FPS	160 FPS
medium	126 FPS	127 FPS
high	98 FPS	101 FPS
ultra	78 FPS	79 FPS
4K
low	73 FPS	73 FPS
medium	61 FPS	61 FPS
high	47 FPS	48 FPS
ultra	39 FPS	40 FPS

Open EPYC 7543 Open Ryzen Threadripper PRO 3975WX

Path of Exile 2

Path of Exile 2

Counter-Strike 2

Preset	EPYC 7543	Ryzen Threadripper PRO 3975WX
1080p
low	507 FPS	579 FPS
medium	443 FPS	499 FPS
high	354 FPS	383 FPS
ultra	288 FPS	327 FPS
1440p
low	417 FPS	485 FPS
medium	373 FPS	425 FPS
high	308 FPS	338 FPS
ultra	243 FPS	274 FPS
4K
low	257 FPS	304 FPS
medium	234 FPS	270 FPS
high	205 FPS	231 FPS
ultra	171 FPS	202 FPS

Open EPYC 7543 Open Ryzen Threadripper PRO 3975WX

Counter-Strike 2

Counter-Strike 2

League of Legends

Preset	EPYC 7543	Ryzen Threadripper PRO 3975WX
1080p
low	850 FPS	681 FPS
medium	705 FPS	564 FPS
high	657 FPS	497 FPS
ultra	580 FPS	425 FPS
1440p
low	612 FPS	570 FPS
medium	506 FPS	479 FPS
high	464 FPS	424 FPS
ultra	405 FPS	364 FPS
4K
low	437 FPS	417 FPS
medium	339 FPS	333 FPS
high	303 FPS	293 FPS
ultra	245 FPS	234 FPS

Open EPYC 7543 Open Ryzen Threadripper PRO 3975WX

League of Legends

League of Legends

Valorant

Preset	EPYC 7543	Ryzen Threadripper PRO 3975WX
1080p
low	992 FPS	1020 FPS
medium	900 FPS	917 FPS
high	775 FPS	765 FPS
ultra	671 FPS	664 FPS
1440p
low	763 FPS	802 FPS
medium	665 FPS	701 FPS
high	569 FPS	584 FPS
ultra	490 FPS	496 FPS
4K
low	547 FPS	559 FPS
medium	488 FPS	504 FPS
high	428 FPS	437 FPS
ultra	370 FPS	373 FPS

Open EPYC 7543 Open Ryzen Threadripper PRO 3975WX

Valorant

Valorant

Check FPS for your specific build

Technical Specifications

Side-by-side comparison of EPYC 7543 and Ryzen Threadripper PRO 3975WX

EPYC 7543

The EPYC 7543 is manufactured by AMD. It was released in 15 March 2021 (4 years ago). It is based on the Milan (2021−2023) architecture. It features 32 cores and 64 threads. Base frequency is 2.8 GHz, with boost up to 3.7 GHz. L3 cache: 256 MB (total). L2 cache: 512 kB (per core). Built on 7 nm+ process technology. Socket: SP3. Thermal design power (TDP): 225 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,952 points. Launch price was $3,761.

Ryzen Threadripper PRO 3975WX

The Ryzen Threadripper PRO 3975WX is manufactured by AMD. It was released in 2020-07-14. It is based on the Matisse (2019−2020) architecture. It features 32 cores and 64 threads. Base frequency is 3.5 GHz, with boost up to 4.2 GHz. L3 cache: 128 MB. L2 cache: 512K (per core). Built on 7 nm, 12 nm process technology. Socket: sWRX8. Thermal design power (TDP): 280 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,261 points. Launch price was $4,499.

⚡

Processing Power

Both the EPYC 7543 and Ryzen Threadripper PRO 3975WX share an identical 32-core/64-thread configuration. Boost clocks reach 3.7 GHz on the EPYC 7543 versus 4.2 GHz on the Ryzen Threadripper PRO 3975WX — a 12.7% clock advantage for the Ryzen Threadripper PRO 3975WX (base: 2.8 GHz vs 3.5 GHz). The EPYC 7543 uses the Milan (2021−2023) architecture (7 nm+), while the Ryzen Threadripper PRO 3975WX uses Matisse (2019−2020) (7 nm, 12 nm). In PassMark, the EPYC 7543 scores 62,952 against the Ryzen Threadripper PRO 3975WX's 62,261 — a 1.1% lead for the EPYC 7543. L3 cache: 256 MB (total) on the EPYC 7543 vs 128 MB on the Ryzen Threadripper PRO 3975WX.

Feature	EPYC 7543	Ryzen Threadripper PRO 3975WX
Cores / Threads	32 / 64	32 / 64
Boost Clock	3.7 GHz	4.2 GHz+14%
Base Clock	2.8 GHz	3.5 GHz+25%
L3 Cache	256 MB (total)+100%	128 MB
L2 Cache	512 kB (per core)	512K (per core)
Process	7 nm+	7 nm, 12 nm
Architecture	Milan (2021−2023)	Matisse (2019−2020)
PassMark	62,952+1%	62,261
Cinebench R23 Multi	—	42,986
Geekbench 6 Single	—	1,260
Geekbench 6 Multi	—	25,211

🧠

Memory & Platform

The EPYC 7543 uses the SP3 socket (PCIe 4.0), while the Ryzen Threadripper PRO 3975WX uses sWRX8 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 3200 on the EPYC 7543 versus DDR4-3200 on the Ryzen Threadripper PRO 3975WX — the EPYC 7543 supports 199.5% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7543 supports up to 4096 of RAM compared to 2048 GB — 66.7% more capacity for professional workloads. Both feature 8-channel memory with ECC support. Both provide 128 PCIe lanes. Chipset compatibility: SP3 (EPYC 7543) and AMD WRX80 (Ryzen Threadripper PRO 3975WX).

Feature	EPYC 7543	Ryzen Threadripper PRO 3975WX
Socket	SP3	sWRX8
PCIe Generation	PCIe 4.0	PCIe 4.0
Max RAM Speed	3200+79900%	DDR4-3200
Max RAM Capacity	4096	2048 GB+52428700%
RAM Channels	8	8
ECC Support	Yes	Yes
PCIe Lanes	128	128

🔧

Advanced Features

Only the Ryzen Threadripper PRO 3975WX has an unlocked multiplier for overclocking — a significant advantage for enthusiasts seeking extra performance. Virtualization support: VT-x, VT-d (EPYC 7543) vs true (Ryzen Threadripper PRO 3975WX). Direct competitor: EPYC 7543 rivals Xeon Platinum 8380; Ryzen Threadripper PRO 3975WX rivals Xeon W-3375.

Feature	EPYC 7543	Ryzen Threadripper PRO 3975WX
Integrated GPU	No	No
IGPU Model	None	None
Unlocked	No	Yes
AVX-512	No	No
Virtualization	VT-x, VT-d	true

💰

Value Analysis

The EPYC 7543 launched at $10257 MSRP, while the Ryzen Threadripper PRO 3975WX debuted at $1337. On MSRP ($10257 vs $1337), the Ryzen Threadripper PRO 3975WX is $8920 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 7543 delivers 6.1 pts/$ vs 46.6 pts/$ for the Ryzen Threadripper PRO 3975WX — making the Ryzen Threadripper PRO 3975WX the 153.4% better value option.