Xeon E-2378G vs Xeon Silver 4216

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

Xeon E-2378G

2021

Why buy it

✅Better for gaming: +52.7% higher average FPS across 3 shared CPU benchmark tests.
✅Draws 80W instead of 100W, a 20W reduction.

Trade-offs

❌Smaller total L3 cache (16 MB vs 22 MB).
❌No AVX-512 support for niche heavy compute workloads where it can matter.

Xeon Silver 4216

2019

Why buy it

✅+37.5% larger total L3 cache (22 MB vs 16 MB).
✅100+% more PCIe lanes (48 vs 0) for storage and expansion-heavy builds.
✅AVX-512 support for select workstation, AI, and scientific workloads.

Trade-offs

❌Worse for gaming: lower average FPS than Xeon E-2378G across 3 shared CPU benchmark tests.
❌Lower PassMark (21,022 vs 21,153).
❌Launch MSRP is still $1,011 MSRP, while Xeon E-2378G mostly shows up through inconsistent older-market listings.
❌25% higher power demand at 100W vs 80W.

Xeon E-2378G

2021

Xeon Silver 4216

2019

Why buy it

✅Better for gaming: +52.7% higher average FPS across 3 shared CPU benchmark tests.
✅Draws 80W instead of 100W, a 20W reduction.

Why buy it

✅+37.5% larger total L3 cache (22 MB vs 16 MB).
✅100+% more PCIe lanes (48 vs 0) for storage and expansion-heavy builds.
✅AVX-512 support for select workstation, AI, and scientific workloads.

Trade-offs

❌Smaller total L3 cache (16 MB vs 22 MB).
❌No AVX-512 support for niche heavy compute workloads where it can matter.

Trade-offs

❌Worse for gaming: lower average FPS than Xeon E-2378G across 3 shared CPU benchmark tests.
❌Lower PassMark (21,022 vs 21,153).
❌Launch MSRP is still $1,011 MSRP, while Xeon E-2378G mostly shows up through inconsistent older-market listings.
❌25% higher power demand at 100W vs 80W.

Quick Answers

So, is Xeon E-2378G better than Xeon Silver 4216?

Yes. Xeon E-2378G is the better overall CPU here. You are getting a 52.7% average FPS lead across 3 shared CPU game tests in our data, 0.6% better PassMark, and the stronger long-term platform, which makes it the stronger all-around choice.

Which one is better for gaming?

If gaming is the priority, Xeon E-2378G is the better pick here. According to our tests, it delivers 52.7% more average FPS across 3 shared CPU game tests.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, Xeon E-2378G is the better fit. You are getting 0.6% better PassMark, backed by 8 cores and 16 threads.

Which one is the smarter buy today, not just the cheaper CPU?

Xeon E-2378G is still the faster CPU overall, but Xeon Silver 4216 makes more sense if price matters more than absolute performance. Xeon E-2378G is at an unclear MSRP at unclear MSRP versus $1,011 MSRP, and it gives you a 52.7% average FPS lead across 3 shared CPU game tests in our data. Xeon Silver 4216 is also 100.0% better value on MSRP (20.8 vs 0.0 PassMark/$), which is why it is easier to justify for price-conscious builds on paper.

Which one is more future-proof for 2026 and beyond?

Xeon E-2378G is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2021 vs 2019) and more multi-core headroom with 8 cores / 16 threads instead of 16/32. That extra compute headroom should age better as games, background tasks, and creator workloads get heavier.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Xeon E-2378G Benchmark Check

Xeon Silver 4216 Benchmark Check

Path of Exile 2

Preset	Xeon E-2378G	Xeon Silver 4216
1080p
low	292 FPS	174 FPS
medium	260 FPS	139 FPS
high	219 FPS	111 FPS
ultra	188 FPS	87 FPS
1440p
low	240 FPS	139 FPS
medium	192 FPS	109 FPS
high	157 FPS	86 FPS
ultra	138 FPS	68 FPS
4K
low	166 FPS	66 FPS
medium	135 FPS	55 FPS
high	104 FPS	43 FPS
ultra	91 FPS	34 FPS

Open Xeon E-2378G Open Xeon Silver 4216

Path of Exile 2

Path of Exile 2

Counter-Strike 2

Preset	Xeon E-2378G	Xeon Silver 4216
1080p
low	529 FPS	188 FPS
medium	520 FPS	167 FPS
high	453 FPS	145 FPS
ultra	399 FPS	118 FPS
1440p
low	529 FPS	162 FPS
medium	484 FPS	148 FPS
high	417 FPS	128 FPS
ultra	353 FPS	104 FPS
4K
low	395 FPS	105 FPS
medium	335 FPS	97 FPS
high	316 FPS	85 FPS
ultra	268 FPS	68 FPS

Open Xeon E-2378G Open Xeon Silver 4216

Counter-Strike 2

Counter-Strike 2

League of Legends

Preset	Xeon E-2378G	Xeon Silver 4216
1080p
low	529 FPS	526 FPS
medium	529 FPS	526 FPS
high	529 FPS	526 FPS
ultra	529 FPS	526 FPS
1440p
low	529 FPS	526 FPS
medium	529 FPS	526 FPS
high	514 FPS	526 FPS
ultra	441 FPS	526 FPS
4K
low	529 FPS	473 FPS
medium	454 FPS	372 FPS
high	404 FPS	331 FPS
ultra	339 FPS	269 FPS

Open Xeon E-2378G Open Xeon Silver 4216

League of Legends

League of Legends

Valorant

Preset	Xeon E-2378G	Xeon Silver 4216
1080p
low	529 FPS	526 FPS
medium	529 FPS	526 FPS
high	529 FPS	526 FPS
ultra	529 FPS	526 FPS
1440p
low	529 FPS	526 FPS
medium	529 FPS	526 FPS
high	529 FPS	508 FPS
ultra	529 FPS	430 FPS
4K
low	529 FPS	466 FPS
medium	529 FPS	417 FPS
high	503 FPS	372 FPS
ultra	436 FPS	321 FPS

Open Xeon E-2378G Open Xeon Silver 4216

Valorant

Valorant

Check FPS for your specific build

Technical Specifications

Side-by-side comparison of Xeon E-2378G and Xeon Silver 4216

Xeon E-2378G

The Xeon E-2378G is manufactured by Intel. It was released in 2015-01-01. It is based on the Rocket Lake-E (2021) architecture. It features 8 cores and 16 threads. Base frequency is 2.8 GHz, with boost up to 5.1 GHz. L3 cache: 16 MB (total). L2 cache: 512K (per core). Built on 14 nm process technology. Socket: LGA1200. Thermal design power (TDP): 80 Watt. Memory support: DDR4-3200. Passmark benchmark score: 21,153 points. Launch price was $800.

Xeon Silver 4216

The Xeon Silver 4216 is manufactured by Intel. It was released in 2 April 2019 (6 years ago). It is based on the Cascade Lake (2019−2020) architecture. It features 16 cores and 32 threads. Base frequency is 2.1 GHz, with boost up to 3.2 GHz. L3 cache: 22 MB. L2 cache: 16 MB. Built on 14 nm process technology. Socket: LGA3647. Thermal design power (TDP): 100 Watt. Memory support: DDR4-2400. Passmark benchmark score: 21,022 points. Launch price was $1,002.

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Processing Power

The Xeon E-2378G packs 8 cores / 16 threads, while the Xeon Silver 4216 offers 16 cores / 32 threads — the Xeon Silver 4216 has 8 more cores. Boost clocks reach 5.1 GHz on the Xeon E-2378G versus 3.2 GHz on the Xeon Silver 4216 — a 45.8% clock advantage for the Xeon E-2378G (base: 2.8 GHz vs 2.1 GHz). The Xeon E-2378G uses the Rocket Lake-E (2021) architecture (14 nm), while the Xeon Silver 4216 uses Cascade Lake (2019−2020) (14 nm). In PassMark, the Xeon E-2378G scores 21,153 against the Xeon Silver 4216's 21,022 — a 0.6% lead for the Xeon E-2378G. L3 cache: 16 MB (total) on the Xeon E-2378G vs 22 MB on the Xeon Silver 4216.

Feature	Xeon E-2378G	Xeon Silver 4216
Cores / Threads	8 / 16	16 / 32+100%
Boost Clock	5.1 GHz+59%	3.2 GHz
Base Clock	2.8 GHz+33%	2.1 GHz
L3 Cache	16 MB (total)	22 MB+38%
L2 Cache	512K (per core)	16 MB+3100%
Process	14 nm	14 nm
Architecture	Rocket Lake-E (2021)	Cascade Lake (2019−2020)
PassMark	21,153	21,022
Cinebench R23 Multi	—	16,500
Geekbench 6 Single	—	1,013
Geekbench 6 Multi	—	12,286

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Memory & Platform

The Xeon E-2378G uses the LGA1200 socket (PCIe 4.0), while the Xeon Silver 4216 uses LGA3647 (PCIe 3.0) — making them incompatible on the same motherboard.

Feature	Xeon E-2378G	Xeon Silver 4216
Socket	LGA1200	LGA3647
PCIe Generation	PCIe 4.0+33%	PCIe 3.0
Max RAM Speed	—	DDR4-2400
Max RAM Capacity	—	1024 GB
RAM Channels	—	6
ECC Support	—	Yes
PCIe Lanes	—	48

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Advanced Features

Virtualization: not specified (Xeon E-2378G) / VT-x, VT-d, EPT (Xeon Silver 4216). Primary use case: Xeon Silver 4216 targets Server / Edge computing. Direct competitor: Xeon Silver 4216 rivals EPYC 7262.