Xeon E5-2643 v3 vs Xeon Silver 4110

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

Xeon E5-2643 v3

2014

Why buy it

✅Better for gaming: +17.8% higher average FPS across 4 shared CPU benchmark tests.
✅+81.8% larger total L3 cache (20 MB vs 11 MB).

Trade-offs

❌Lower PassMark (10,265 vs 10,314).
❌Launch MSRP is still $219 MSRP, while Xeon Silver 4110 mostly shows up through inconsistent older-market listings.
❌58.8% higher power demand at 135W vs 85W.

Xeon Silver 4110

2017

Why buy it

✅+0.5% higher PassMark.
✅Draws 85W instead of 135W, a 50W reduction.
✅100+% more PCIe lanes (48 vs 0) for storage and expansion-heavy builds.

Trade-offs

❌Worse for gaming: lower average FPS than Xeon E5-2643 v3 across 4 shared CPU benchmark tests.
❌Smaller total L3 cache (11 MB vs 20 MB).

Xeon E5-2643 v3

2014

Xeon Silver 4110

2017

Why buy it

✅Better for gaming: +17.8% higher average FPS across 4 shared CPU benchmark tests.
✅+81.8% larger total L3 cache (20 MB vs 11 MB).

Why buy it

✅+0.5% higher PassMark.
✅Draws 85W instead of 135W, a 50W reduction.
✅100+% more PCIe lanes (48 vs 0) for storage and expansion-heavy builds.

Trade-offs

❌Lower PassMark (10,265 vs 10,314).
❌Launch MSRP is still $219 MSRP, while Xeon Silver 4110 mostly shows up through inconsistent older-market listings.
❌58.8% higher power demand at 135W vs 85W.

Trade-offs

❌Worse for gaming: lower average FPS than Xeon E5-2643 v3 across 4 shared CPU benchmark tests.
❌Smaller total L3 cache (11 MB vs 20 MB).

Quick Answers

So, is Xeon Silver 4110 better than Xeon E5-2643 v3?

It depends on what matters more to you. For gaming, Xeon E5-2643 v3 is ahead with a 17.8% average FPS lead across 4 shared CPU game tests in our data. For rendering, compiling, streaming, and heavier multitasking, Xeon Silver 4110 pulls ahead with 0.5% better PassMark. Xeon E5-2643 v3 also has the bigger cache pool with 81.8% larger total L3 cache (20 MB vs 11 MB).

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, Xeon Silver 4110 is the better fit. You are getting 0.5% better PassMark, backed by 8 cores and 16 threads.

Which one is the smarter buy today, not just the cheaper CPU?

Xeon Silver 4110 is still the faster CPU overall, but Xeon E5-2643 v3 makes more sense if price matters more than absolute performance. Xeon Silver 4110 is at an unclear MSRP at unclear MSRP versus $219 MSRP, and it gives you 0.5% better PassMark. The trade-off is that Xeon E5-2643 v3 is still the better pure gaming CPU with a 17.8% average FPS lead across 4 shared CPU game tests in our data. Xeon E5-2643 v3 is also 100.0% better value on MSRP (46.9 vs 0.0 PassMark/$), which is why it is easier to justify for price-conscious builds on paper.

Which one is more future-proof for 2026 and beyond?

Xeon Silver 4110 is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2017 vs 2014), more multi-core headroom with 8 cores / 16 threads instead of 6/12, and AVX-512 support for heavier modern compute workloads. That extra compute headroom should age better as games, background tasks, and creator workloads get heavier.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Xeon E5-2643 v3 Benchmark Check

Xeon Silver 4110 Benchmark Check

Path of Exile 2

Preset	Xeon E5-2643 v3	Xeon Silver 4110
1080p
low	172 FPS	169 FPS
medium	147 FPS	134 FPS
high	119 FPS	108 FPS
ultra	98 FPS	87 FPS
1440p
low	143 FPS	138 FPS
medium	119 FPS	107 FPS
high	95 FPS	85 FPS
ultra	77 FPS	68 FPS
4K
low	65 FPS	65 FPS
medium	57 FPS	54 FPS
high	45 FPS	43 FPS
ultra	36 FPS	34 FPS

Open Xeon E5-2643 v3 Open Xeon Silver 4110

Path of Exile 2

Path of Exile 2

Counter-Strike 2

Preset	Xeon E5-2643 v3	Xeon Silver 4110
1080p
low	257 FPS	124 FPS
medium	257 FPS	110 FPS
high	235 FPS	103 FPS
ultra	195 FPS	82 FPS
1440p
low	257 FPS	110 FPS
medium	237 FPS	100 FPS
high	205 FPS	93 FPS
ultra	173 FPS	75 FPS
4K
low	192 FPS	91 FPS
medium	167 FPS	84 FPS
high	147 FPS	75 FPS
ultra	112 FPS	58 FPS

Open Xeon E5-2643 v3 Open Xeon Silver 4110

Counter-Strike 2

Counter-Strike 2

League of Legends

Preset	Xeon E5-2643 v3	Xeon Silver 4110
1080p
low	257 FPS	258 FPS
medium	257 FPS	258 FPS
high	257 FPS	258 FPS
ultra	257 FPS	258 FPS
1440p
low	257 FPS	258 FPS
medium	257 FPS	258 FPS
high	257 FPS	258 FPS
ultra	257 FPS	258 FPS
4K
low	257 FPS	258 FPS
medium	257 FPS	258 FPS
high	257 FPS	258 FPS
ultra	245 FPS	258 FPS

Open Xeon E5-2643 v3 Open Xeon Silver 4110

League of Legends

League of Legends

Valorant

Preset	Xeon E5-2643 v3	Xeon Silver 4110
1080p
low	257 FPS	258 FPS
medium	257 FPS	258 FPS
high	257 FPS	258 FPS
ultra	257 FPS	258 FPS
1440p
low	257 FPS	258 FPS
medium	257 FPS	258 FPS
high	257 FPS	258 FPS
ultra	257 FPS	258 FPS
4K
low	257 FPS	258 FPS
medium	257 FPS	258 FPS
high	257 FPS	258 FPS
ultra	257 FPS	258 FPS

Open Xeon E5-2643 v3 Open Xeon Silver 4110

Valorant

Valorant

Check FPS for your specific build

Technical Specifications

Side-by-side comparison of Xeon E5-2643 v3 and Xeon Silver 4110

Xeon E5-2643 v3

The Xeon E5-2643 v3 is manufactured by Intel. It was released in 2015-01-01. It is based on the Haswell-EP (2014−2015) architecture. It features 6 cores and 12 threads. Base frequency is 3.4 GHz, with boost up to 3.7 GHz. L3 cache: 20 MB (total). L2 cache: 256K (per core). Built on 22 nm process technology. Socket: LGA2011. Thermal design power (TDP): 135 Watt. Memory support: DDR4-1600, DDR4-1866, DDR4-2133. Passmark benchmark score: 10,265 points. Launch price was $800.

Xeon Silver 4110

The Xeon Silver 4110 is manufactured by Intel. It was released in 11 July 2017 (8 years ago). It is based on the Skylake (server) (2017−2018) architecture. It features 8 cores and 16 threads. Base frequency is 2.1 GHz, with boost up to 3 GHz. L3 cache: 11 MB. L2 cache: 8 MB. Built on 14 nm process technology. Socket: LGA3647. Thermal design power (TDP): 85 Watt. Memory support: DDR4-2400. Passmark benchmark score: 10,314 points. Launch price was $501.

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Processing Power

The Xeon E5-2643 v3 packs 6 cores / 12 threads, while the Xeon Silver 4110 offers 8 cores / 16 threads — the Xeon Silver 4110 has 2 more cores. Boost clocks reach 3.7 GHz on the Xeon E5-2643 v3 versus 3 GHz on the Xeon Silver 4110 — a 20.9% clock advantage for the Xeon E5-2643 v3 (base: 3.4 GHz vs 2.1 GHz). The Xeon E5-2643 v3 uses the Haswell-EP (2014−2015) architecture (22 nm), while the Xeon Silver 4110 uses Skylake (server) (2017−2018) (14 nm). In PassMark, the Xeon E5-2643 v3 scores 10,265 against the Xeon Silver 4110's 10,314 — a 0.5% lead for the Xeon Silver 4110. L3 cache: 20 MB (total) on the Xeon E5-2643 v3 vs 11 MB on the Xeon Silver 4110.

Feature	Xeon E5-2643 v3	Xeon Silver 4110
Cores / Threads	6 / 12	8 / 16+33%
Boost Clock	3.7 GHz+23%	3 GHz
Base Clock	3.4 GHz+62%	2.1 GHz
L3 Cache	20 MB (total)+82%	11 MB
L2 Cache	256K (per core)	8 MB+3100%
Process	22 nm	14 nm-36%
Architecture	Haswell-EP (2014−2015)	Skylake (server) (2017−2018)
PassMark	10,265	10,314

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Memory & Platform

The Xeon E5-2643 v3 uses the LGA2011 socket (PCIe 5.0), while the Xeon Silver 4110 uses LGA3647 (PCIe 3.0) — making them incompatible on the same motherboard.