EPYC 4345P vs Xeon Platinum 8268

AMD

EPYC 4345P

8 Cores16 Thrd65 WWMax: 5.5 GHz2025

Popular choices:

VS
Intel

Xeon Platinum 8268

24 Cores48 Thrd205 WWMax: 3.9 GHz2019

Popular choices:

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

EPYC 4345P

2025

Why buy it

  • Better for gaming: +8.0% higher average FPS across 4 shared CPU benchmark tests.
  • Costs $5,973 less on MSRP ($329 MSRP vs $6,302 MSRP).
  • Delivers 1866.0% more PassMark for each dollar spent, at 109.4 vs 5.6 PassMark/$ ($329 MSRP vs $6,302 MSRP).
  • Draws 65W instead of 205W, a 140W reduction.
  • Newer platform on AM5 with DDR5 support instead of LGA3647 and DDR4.

Trade-offs

  • Fewer obvious downsides in this matchup outside of normal market pricing swings.

Xeon Platinum 8268

2019

Why buy it

  • 71.4% more PCIe lanes (48 vs 28) for storage and expansion-heavy builds.

Trade-offs

  • Worse for gaming: lower average FPS than EPYC 4345P across 4 shared CPU benchmark tests.
  • Lower PassMark (35,081 vs 36,006).
  • Lower PassMark per dollar, at 5.6 vs 109.4 PassMark/$ ($6,302 MSRP vs $329 MSRP).
  • 215.4% higher power demand at 205W vs 65W.
  • Older platform position on LGA3647 with DDR4, while EPYC 4345P moves to AM5 and DDR5.

Quick Answers

So, is EPYC 4345P better than Xeon Platinum 8268?
Yes. EPYC 4345P is the better overall CPU here. You are getting a 8.0% average FPS lead across 4 shared CPU game tests in our data, 2.6% better PassMark, and the stronger long-term platform, which makes it the stronger all-around choice.
Which one is better for gaming?
If gaming is the priority, EPYC 4345P is the better pick here. According to our tests, it delivers 8.0% more average FPS across 4 shared CPU game tests.
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, EPYC 4345P is the better fit. You are getting 2.6% better PassMark, backed by 8 cores and 16 threads.
Which one is the smarter buy today, not just the cheaper CPU?
EPYC 4345P is the smarter buy today. EPYC 4345P is $5,973 cheaper on MSRP at $329 MSRP versus $6,302 MSRP, and it gives you a 8.0% average FPS lead across 4 shared CPU game tests in our data. It is also 1866.0% better value on MSRP (109.4 vs 5.6 PassMark/$), so the better CPU is not just faster, it is also the cleaner value play on paper.
Which one is more future-proof for 2026 and beyond?
EPYC 4345P is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2025 vs 2019), a healthier platform with AM5 and DDR5 instead of LGA3647, and more multi-core headroom with 8 cores / 16 threads instead of 24/48. That should give you a better long-term upgrade path for motherboard, RAM, and future CPU swaps.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Path of Exile 2

Path of Exile 2

PresetEPYC 4345PXeon Platinum 8268
1080p
low257 FPS194 FPS
medium239 FPS157 FPS
high207 FPS126 FPS
ultra178 FPS98 FPS
1440p
low220 FPS159 FPS
medium185 FPS124 FPS
high153 FPS96 FPS
ultra134 FPS76 FPS
4K
low153 FPS72 FPS
medium128 FPS60 FPS
high100 FPS47 FPS
ultra86 FPS38 FPS
Counter-Strike 2

Counter-Strike 2

PresetEPYC 4345PXeon Platinum 8268
1080p
low630 FPS424 FPS
medium526 FPS370 FPS
high436 FPS303 FPS
ultra393 FPS249 FPS
1440p
low537 FPS366 FPS
medium470 FPS322 FPS
high395 FPS266 FPS
ultra337 FPS212 FPS
4K
low315 FPS228 FPS
medium281 FPS203 FPS
high265 FPS180 FPS
ultra232 FPS148 FPS
League of Legends

League of Legends

PresetEPYC 4345PXeon Platinum 8268
1080p
low900 FPS877 FPS
medium747 FPS877 FPS
high664 FPS872 FPS
ultra570 FPS787 FPS
1440p
low725 FPS731 FPS
medium581 FPS632 FPS
high504 FPS600 FPS
ultra425 FPS537 FPS
4K
low501 FPS468 FPS
medium415 FPS368 FPS
high373 FPS328 FPS
ultra311 FPS269 FPS
Valorant

Valorant

PresetEPYC 4345PXeon Platinum 8268
1080p
low900 FPS877 FPS
medium900 FPS848 FPS
high856 FPS733 FPS
ultra772 FPS637 FPS
1440p
low855 FPS736 FPS
medium756 FPS646 FPS
high663 FPS555 FPS
ultra579 FPS476 FPS
4K
low570 FPS531 FPS
medium509 FPS473 FPS
high459 FPS416 FPS
ultra400 FPS361 FPS

Technical Specifications

Side-by-side comparison of EPYC 4345P and Xeon Platinum 8268

AMD

EPYC 4345P

The EPYC 4345P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 8 cores and 16 threads. Base frequency is 3.8 GHz, with boost up to 5.5 GHz. L3 cache: 32 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 65 Watt. Memory support: DDR5. Passmark benchmark score: 36,006 points. Launch price was $329.

Intel

Xeon Platinum 8268

The Xeon Platinum 8268 is manufactured by Intel. It was released in 11 December 2018 (6 years ago). It is based on the Cascade Lake-SP (2018) architecture. It features 24 cores and 48 threads. Base frequency is 2.9 GHz, with boost up to 3.9 GHz. L3 cache: 35.75 MB (total). L2 cache: 1 MB (per core). Built on 14 nm process technology. Socket: LGA3647. Thermal design power (TDP): 205 Watt. Memory support: DDR4-2933. Passmark benchmark score: 35,081 points. Launch price was $6,302.

Processing Power

The EPYC 4345P packs 8 cores / 16 threads, while the Xeon Platinum 8268 offers 24 cores / 48 threads — the Xeon Platinum 8268 has 16 more cores. Boost clocks reach 5.5 GHz on the EPYC 4345P versus 3.9 GHz on the Xeon Platinum 8268 — a 34% clock advantage for the EPYC 4345P (base: 3.8 GHz vs 2.9 GHz). The EPYC 4345P uses the Grado (2025) architecture (4 nm), while the Xeon Platinum 8268 uses Cascade Lake-SP (2018) (14 nm). In PassMark, the EPYC 4345P scores 36,006 against the Xeon Platinum 8268's 35,081 — a 2.6% lead for the EPYC 4345P. L3 cache: 32 MB (total) on the EPYC 4345P vs 35.75 MB (total) on the Xeon Platinum 8268.

FeatureEPYC 4345PXeon Platinum 8268
Cores / Threads
8 / 16
24 / 48+200%
Boost Clock
5.5 GHz+41%
3.9 GHz
Base Clock
3.8 GHz+31%
2.9 GHz
L3 Cache
32 MB (total)
35.75 MB (total)+12%
L2 Cache
1 MB (per core)
1 MB (per core)
Process
4 nm-71%
14 nm
Architecture
Grado (2025)
Cascade Lake-SP (2018)
PassMark
36,006+3%
35,081
Cinebench R23 Multi
24,500
Geekbench 6 Single
1,394
Geekbench 6 Multi
12,046
🧠

Memory & Platform

The EPYC 4345P uses the AM5 socket (PCIe 4.0), while the Xeon Platinum 8268 uses LGA3647 (PCIe 3.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 5600 on the EPYC 4345P versus DDR4-2933 on the Xeon Platinum 8268 — the EPYC 4345P supports 199.7% faster memory, which can translate to measurable gains in memory-sensitive workloads. The Xeon Platinum 8268 supports up to 1024 GB of RAM compared to 128 155.6% more capacity for professional workloads. Memory channels: 2 (EPYC 4345P) vs 6 (Xeon Platinum 8268). PCIe lanes: 28 (EPYC 4345P) vs 48 (Xeon Platinum 8268) — the Xeon Platinum 8268 offers 20 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AM5 (EPYC 4345P) and C621,Lewisburg (Xeon Platinum 8268).

FeatureEPYC 4345PXeon Platinum 8268
Socket
AM5
LGA3647
PCIe Generation
PCIe 4.0+33%
PCIe 3.0
Max RAM Speed
5600+139900%
DDR4-2933
Max RAM Capacity
128
1024 GB+838860700%
RAM Channels
2
6+200%
ECC Support
Yes
Yes
PCIe Lanes
28
48+71%
🔧

Advanced Features

Neither processor supports overclocking. Both support AVX-512 instructions, benefiting scientific computing, AI inference, and encryption workloads. Virtualization support: AMD-V, IOMMU (EPYC 4345P) vs VT-x, VT-d, EPT (Xeon Platinum 8268). The EPYC 4345P includes integrated graphics (AMD Radeon Graphics), while the Xeon Platinum 8268 requires a dedicated GPU. Primary use case: Xeon Platinum 8268 targets High-end Server. Direct competitor: EPYC 4345P rivals Xeon E-2488; Xeon Platinum 8268 rivals EPYC 7452.

FeatureEPYC 4345PXeon Platinum 8268
Integrated GPU
Yes
No
IGPU Model
AMD Radeon Graphics
Unlocked
No
No
AVX-512
Yes
Yes
Virtualization
AMD-V, IOMMU
VT-x, VT-d, EPT
Target Use
High-end Server
💰

Value Analysis

The EPYC 4345P launched at $329 MSRP, while the Xeon Platinum 8268 debuted at $6302. On MSRP ($329 vs $6302), the EPYC 4345P is $5973 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 4345P delivers 109.4 pts/$ vs 5.6 pts/$ for the Xeon Platinum 8268 — making the EPYC 4345P the 180.6% better value option.

FeatureEPYC 4345PXeon Platinum 8268
MSRP
$329-95%
$6302
Performance per Dollar
109.4+1854%
5.6
Release Date
2025
2019