Quadro P4000 vs Radeon PRO W6600M

NVIDIA

Quadro P4000

2017Core: 1202 MHzBoost: 1480 MHz

Popular choices:

VS
AMD

Radeon PRO W6600M

2021Core: 1224 MHzBoost: 2034 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Quadro P4000

2017

Why buy it

  • Delivers 100+% more G3D Mark for each dollar spent, at 14.0 vs 0 G3D/$ ($815 MSRP vs Unknown MSRP).

Trade-offs

  • Lower average FPS than Radeon PRO W6600M across 50 tracked games in our benchmark data.
  • Poor future-proofing: 2017-era hardware with 8 GB of VRAM is already a legacy-tier option for modern games.
  • 16.7% higher power demand at 105W vs 90W.

Radeon PRO W6600M

2021

Why buy it

  • 10.5% more average FPS across 50 tracked games in our benchmark data.
  • More future proof: RDNA 2.0 (2020−2025) on 7nm with a newer platform for upcoming games.
  • Draws 90W instead of 105W, a 15W reduction.

Trade-offs

  • Lower G3D Mark per dollar, at 0 vs 14.0 G3D/$ (Unknown MSRP vs $815 MSRP).

Quick Answers

So, is Radeon PRO W6600M better than Quadro P4000?
Yes. Radeon PRO W6600M is clearly the better overall GPU here. Radeon PRO W6600M averages 10.5% more FPS across 50 tracked games in our benchmark data. You are also looking at 11,407 vs 11,431 in G3D Mark. On top of that, Radeon PRO W6600M is a 2021 card with FSR upscaling, while Quadro P4000 is a 2017 model from an older generation with no meaningful modern upscaling stack. So this is not really a tight same-tier comparison. It is more a modern card against an older, weaker alternative.
Which one is more future-proof for 2026 and beyond?
Radeon PRO W6600M is the more future-proof choice for 2026 and beyond. You are getting a newer 2021 generation instead of 2017, better upscaling support with FSR Upscaling / FSR 4 (2025) instead of no meaningful modern upscaling stack, and a 7nm process instead of 16nm. That broader feature stack should age better as more games lean on modern upscaling and frame-generation support.
Which one is the smarter buy today, not just the cheaper card?
Radeon PRO W6600M is the smarter buy by a wide margin. Radeon PRO W6600M is priced in an unclear MSRP range at an unclear MSRP versus $815 MSRP, and you are getting 10.5% more estimated average FPS across 50 tracked games in our benchmark data and a lower G3D Mark (11,407 vs 11,431). Quadro P4000 really only makes sense now as a very cheap stopgap or a used-market placeholder.
Is Quadro P4000 still worth buying for gaming in 2026?
No, not for a fresh gaming build. Quadro P4000 is 2017 hardware with 8 GB of VRAM, 11,431 in G3D Mark, and no meaningful modern upscaling stack. That is simply too far behind to be an easy modern recommendation.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetQuadro P4000Radeon PRO W6600M
1080p
low111 FPS140 FPS
medium94 FPS118 FPS
high80 FPS103 FPS
ultra53 FPS71 FPS
1440p
low94 FPS112 FPS
medium79 FPS92 FPS
high60 FPS75 FPS
ultra39 FPS52 FPS
4K
low37 FPS50 FPS
medium34 FPS43 FPS
high22 FPS32 FPS
ultra18 FPS28 FPS
Counter-Strike 2

Counter-Strike 2

PresetQuadro P4000Radeon PRO W6600M
1080p
low223 FPS243 FPS
medium190 FPS206 FPS
high146 FPS168 FPS
ultra117 FPS134 FPS
1440p
low164 FPS170 FPS
medium139 FPS142 FPS
high111 FPS112 FPS
ultra88 FPS88 FPS
4K
low96 FPS93 FPS
medium80 FPS78 FPS
high67 FPS65 FPS
ultra51 FPS49 FPS
League of Legends

League of Legends

PresetQuadro P4000Radeon PRO W6600M
1080p
low514 FPS513 FPS
medium412 FPS411 FPS
high343 FPS342 FPS
ultra257 FPS257 FPS
1440p
low386 FPS385 FPS
medium309 FPS308 FPS
high257 FPS257 FPS
ultra193 FPS192 FPS
4K
low257 FPS257 FPS
medium206 FPS205 FPS
high171 FPS171 FPS
ultra129 FPS128 FPS
Valorant

Valorant

PresetQuadro P4000Radeon PRO W6600M
1080p
low250 FPS262 FPS
medium219 FPS231 FPS
high176 FPS186 FPS
ultra147 FPS157 FPS
1440p
low191 FPS199 FPS
medium166 FPS176 FPS
high130 FPS138 FPS
ultra105 FPS113 FPS
4K
low101 FPS117 FPS
medium83 FPS99 FPS
high66 FPS79 FPS
ultra51 FPS60 FPS

Technical Specifications

Side-by-side comparison of Quadro P4000 and Radeon PRO W6600M

NVIDIA

Quadro P4000

The Quadro P4000 is manufactured by NVIDIA. It was released in February 6 2017. It features the Pascal architecture. The core clock ranges from 1202 MHz to 1480 MHz. It has 1792 shading units. The thermal design power (TDP) is 105W. Manufactured using 16 nm process technology. G3D Mark benchmark score: 11,431 points. Launch price was $815.

AMD

Radeon PRO W6600M

The Radeon PRO W6600M is manufactured by AMD. It was released in June 8 2021. It features the RDNA 2.0 architecture. The core clock ranges from 1224 MHz to 2034 MHz. It has 1792 shading units. The thermal design power (TDP) is 90W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 11,407 points.

Graphics Performance

The Quadro P4000 scores 11,431 and the Radeon PRO W6600M reaches 11,407 in the G3D Mark benchmark — just a 0.2% difference, making them near-identical in rasterization performance. The Quadro P4000 is built on Pascal while the Radeon PRO W6600M uses RDNA 2.0, both on 16 nm vs 7 nm. Shader units: 1,792 (Quadro P4000) vs 1,792 (Radeon PRO W6600M). Raw compute: 5.304 TFLOPS (Quadro P4000) vs 7.29 TFLOPS (Radeon PRO W6600M). Boost clocks: 1480 MHz vs 2034 MHz.

FeatureQuadro P4000Radeon PRO W6600M
G3D Mark Score
11,431
11,407
Architecture
Pascal
RDNA 2.0
Process Node
16 nm
7 nm
Shading Units
1792
1792
Compute (TFLOPS)
5.304 TFLOPS
7.29 TFLOPS+37%
Boost Clock
1480 MHz
2034 MHz+37%
ROPs
64
64
TMUs
112
112
L1 Cache
672 KB+31%
512 KB
L2 Cache
2 MB
2 MB

Advanced Features (DLSS/FSR)

FeatureQuadro P4000Radeon PRO W6600M
Upscaling Tech
Upscaling support
FSR Upscaling / FSR 4
Frame Generation
Not Supported
Not Supported
Ray Reconstruction
No
No
Low Latency
Standard
AMD Anti-Lag
💾

Video Memory (VRAM)

Both cards feature 8 GB of GDDR6. Bus width: 256-bit vs 256-bit.

FeatureQuadro P4000Radeon PRO W6600M
VRAM Capacity
8 GB
8 GB
Memory Type
GDDR6
GDDR6
Bus Width
256-bit
256-bit
L2 Cache
2 MB
2 MB
🖥️

Display & API Support

DirectX support: 12.0 (Quadro P4000) vs 12.2 (Radeon PRO W6600M). Vulkan: 1.0 vs 1.2. OpenGL: 4.5 vs 4.6. Maximum simultaneous displays: 4 vs 5.

FeatureQuadro P4000Radeon PRO W6600M
DirectX
12.0
12.2+2%
Vulkan
1.0
1.2+20%
OpenGL
4.5
4.6+2%
Max Displays
4
5+25%
🎬

Media & Encoding

Hardware encoder: 6th Gen NVENC (Quadro P4000) vs VCN 3.0 (Radeon PRO W6600M). Decoder: PureVideo HD VP8 vs VCN 3.0. Supported codecs: MPEG-2,H.264,HEVC (Quadro P4000) vs MPEG-2,H.264,HEVC,VP9,AV1 (Decode) (Radeon PRO W6600M).

FeatureQuadro P4000Radeon PRO W6600M
Encoder
6th Gen NVENC
VCN 3.0
Decoder
PureVideo HD VP8
VCN 3.0
Codecs
MPEG-2,H.264,HEVC
MPEG-2,H.264,HEVC,VP9,AV1 (Decode)
🔌

Power & Dimensions

The Quadro P4000 draws 105W versus the Radeon PRO W6600M's 90W — a 15.4% difference. The Radeon PRO W6600M is more power-efficient. Recommended PSU: 500W (Quadro P4000) vs 500W (Radeon PRO W6600M). Power connectors: PCIe-powered vs PCIe-powered. Card length: 241mm vs 0mm, occupying 1 vs 0 slots. Typical load temperature: 80°C vs 80°C.

FeatureQuadro P4000Radeon PRO W6600M
TDP
105W
90W-14%
Recommended PSU
500W
500W
Power Connector
PCIe-powered
PCIe-powered
Length
241mm
0mm
Height
111mm
0mm
Slots
1
0-100%
Temp (Load)
80°C
80°C
Perf/Watt
108.9
126.7+16%
💰

Value Analysis

The Radeon PRO W6600M is the newer GPU (2021 vs 2017).

FeatureQuadro P4000Radeon PRO W6600M
MSRP
$815
Codename
GP104
Navi 23
Release
February 6 2017
June 8 2021
Ranking
#239
#240