Quadro K4100M vs Radeon Pro 450

NVIDIA

Quadro K4100M

2013Core: 706 MHz

Popular choices:

VS
AMD

Radeon Pro 450

2016Core: 800 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Quadro K4100M

2013

Why buy it

  • Delivers 100+% more G3D Mark for each dollar spent, at 1.8 vs 0 G3D/$ ($1,499 MSRP vs Unknown MSRP).
  • 100% more VRAM for high-resolution textures and newer games (4 GB vs 2 GB).

Trade-offs

  • Very weak future-proofing: 2013-era hardware with 4 GB of VRAM is already obsolete for modern gaming and is hard to recommend today.
  • 185.7% higher power demand at 100W vs 35W.

Radeon Pro 450

2016

Why buy it

  • Draws 35W instead of 100W, a 65W reduction.
  • More future proof: GCN 4.0 (2016−2020) on 14nm with a newer platform for upcoming games.

Trade-offs

  • Less VRAM, with 2 GB vs 4 GB for high-resolution textures and newer games.
  • Very weak future-proofing: 2016-era hardware with 2 GB of VRAM is already obsolete for modern gaming and is hard to recommend today.
  • Lower G3D Mark per dollar, at 0 vs 1.8 G3D/$ (Unknown MSRP vs $1,499 MSRP).

Quick Answers

So, is Quadro K4100M better than Radeon Pro 450?
Yes, but this is not really about a huge raw performance gap. The broader synthetic picture is also very close at 2,773 vs 2,723 in G3D Mark. The bigger reason to prefer Quadro K4100M is the overall package: you are getting no meaningful modern upscaling stack.
Which one is more future-proof for 2026 and beyond?
Quadro K4100M is the more future-proof choice for 2026 and beyond. You are getting more VRAM at 4 GB instead of 2 GB and the stronger feature stack with no meaningful modern upscaling stack instead of FSR upscaling. That extra memory headroom makes it the safer pick for newer games, heavier textures, and higher settings over time.
Which one is the smarter buy today, not just the cheaper card?
Quadro K4100M can still make sense if you find it at the right price, especially around $1,499 MSRP. Quadro K4100M is still the smarter buy for most people, though, because the raw performance is close while the overall package is cleaner. Quadro K4100M is priced in an unclear MSRP range at $1,499 MSRP versus an unclear MSRP, and you are getting 1.8% higher G3D Mark. Radeon Pro 450 is the newer 2016 card, so it still has a real case if you care more about newer architecture and lower power draw (35W vs 100W) than about squeezing out the strongest gaming value today.
When does Radeon Pro 450 make more sense than Quadro K4100M?
Yes. Radeon Pro 450 is still an excellent gaming GPU in 2026: it is still comfortable for 1080p and decent for 1440p, though 4K is more situational. It makes more sense if your priority is newer architecture, lower power draw (35W vs 100W), and staying closer to an unclear MSRP more than squeezing out the extra headroom of Quadro K4100M. The trade-off is that Quadro K4100M currently gives you 1.8% higher G3D Mark. It also leads G3D-per-dollar by 100+%.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetQuadro K4100MRadeon Pro 450
1080p
low80 FPS37 FPS
medium69 FPS22 FPS
high55 FPS16 FPS
ultra36 FPS9 FPS
1440p
low70 FPS25 FPS
medium62 FPS15 FPS
high44 FPS8 FPS
ultra28 FPS4 FPS
4K
low26 FPS9 FPS
medium24 FPS6 FPS
high16 FPS4 FPS
ultra14 FPS3 FPS
Counter-Strike 2

Counter-Strike 2

PresetQuadro K4100MRadeon Pro 450
1080p
low80 FPS45 FPS
medium57 FPS24 FPS
high43 FPS17 FPS
ultra27 FPS11 FPS
1440p
low45 FPS20 FPS
medium29 FPS12 FPS
high22 FPS8 FPS
ultra15 FPS6 FPS
4K
low17 FPS6 FPS
medium11 FPS4 FPS
high9 FPS3 FPS
ultra6 FPS2 FPS
League of Legends

League of Legends

PresetQuadro K4100MRadeon Pro 450
1080p
low125 FPS123 FPS
medium100 FPS98 FPS
high83 FPS82 FPS
ultra62 FPS61 FPS
1440p
low94 FPS92 FPS
medium75 FPS74 FPS
high62 FPS61 FPS
ultra47 FPS46 FPS
4K
low62 FPS61 FPS
medium50 FPS49 FPS
high42 FPS41 FPS
ultra31 FPS31 FPS
Valorant

Valorant

PresetQuadro K4100MRadeon Pro 450
1080p
low125 FPS123 FPS
medium100 FPS98 FPS
high83 FPS82 FPS
ultra62 FPS61 FPS
1440p
low94 FPS92 FPS
medium75 FPS74 FPS
high62 FPS61 FPS
ultra47 FPS46 FPS
4K
low57 FPS59 FPS
medium43 FPS44 FPS
high34 FPS35 FPS
ultra23 FPS25 FPS

Technical Specifications

Side-by-side comparison of Quadro K4100M and Radeon Pro 450

NVIDIA

Quadro K4100M

The Quadro K4100M is manufactured by NVIDIA. It was released in July 23 2013. It features the Kepler architecture. The core clock speed is 706 MHz. It has 1152 shading units. The thermal design power (TDP) is 100W. Manufactured using 28 nm process technology. G3D Mark benchmark score: 2,773 points. Launch price was $1,499.

AMD

Radeon Pro 450

The Radeon Pro 450 is manufactured by AMD. It was released in October 30 2016. It features the GCN 4.0 architecture. The core clock speed is 800 MHz. It has 640 shading units. The thermal design power (TDP) is 35W. Manufactured using 14 nm process technology. G3D Mark benchmark score: 2,723 points.

Graphics Performance

The Quadro K4100M scores 2,773 and the Radeon Pro 450 reaches 2,723 in the G3D Mark benchmark — just a 1.8% difference, making them near-identical in rasterization performance. The Quadro K4100M is built on Kepler while the Radeon Pro 450 uses GCN 4.0, both on 28 nm vs 14 nm. Shader units: 1,152 (Quadro K4100M) vs 640 (Radeon Pro 450). Raw compute: 1.627 TFLOPS (Quadro K4100M) vs 1.024 TFLOPS (Radeon Pro 450).

FeatureQuadro K4100MRadeon Pro 450
G3D Mark Score
2,773+2%
2,723
Architecture
Kepler
GCN 4.0
Process Node
28 nm
14 nm
Shading Units
1152+80%
640
Compute (TFLOPS)
1.627 TFLOPS+59%
1.024 TFLOPS
ROPs
32+100%
16
TMUs
96+140%
40
L1 Cache
96 KB
160 KB+67%
L2 Cache
0.5 MB
1 MB+100%

Advanced Features (DLSS/FSR)

FeatureQuadro K4100MRadeon Pro 450
Upscaling Tech
Upscaling support
FSR Upscaling / FSR 4
Frame Generation
Not Supported
Not Supported
Ray Reconstruction
No
No
Low Latency
Standard
AMD Anti-Lag
💾

Video Memory (VRAM)

The Quadro K4100M comes with 4 GB of VRAM, while the Radeon Pro 450 has 2 GB. The Quadro K4100M offers 100% more capacity, crucial for higher resolutions and texture-heavy games. Bus width: 64-bit vs 64-bit. L2 Cache: 0.5 MB (Quadro K4100M) vs 1 MB (Radeon Pro 450) — the Radeon Pro 450 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro K4100MRadeon Pro 450
VRAM Capacity
4 GB+100%
2 GB
Memory Type
GDDR5
GDDR5
Bus Width
64-bit
64-bit
L2 Cache
0.5 MB
1 MB+100%
🔌

Power & Dimensions

The Quadro K4100M draws 100W versus the Radeon Pro 450's 35W — a 96.3% difference. The Radeon Pro 450 is more power-efficient. Recommended PSU: 350W (Quadro K4100M) vs 350W (Radeon Pro 450). Power connectors: PCIe-powered vs PCIe-powered.

FeatureQuadro K4100MRadeon Pro 450
TDP
100W
35W-65%
Recommended PSU
350W
350W
Power Connector
PCIe-powered
PCIe-powered
Length
1mm
Slots
0
Perf/Watt
27.7
77.8+181%
💰

Value Analysis

The Quadro K4100M launched at $1499 MSRP, while the Radeon Pro 450 launched at $0. The Radeon Pro 450 costs 100+% less ($1499 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 1.8 (Quadro K4100M) vs Infinity (Radeon Pro 450) — the Radeon Pro 450 offers Infinity% better value. The Radeon Pro 450 is the newer GPU (2016 vs 2013).

FeatureQuadro K4100MRadeon Pro 450
MSRP
$1499
$0-100%
Performance per Dollar
1.8
Infinity
Codename
GK104
Baffin
Release
July 23 2013
October 30 2016
Ranking
#604
#612