Quadro K4000 vs Radeon Pro 450

NVIDIA

Quadro K4000

2013Core: 810 MHz

Popular choices:

VS
AMD

Radeon Pro 450

2016Core: 800 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Quadro K4000

2013

Why buy it

  • Delivers 100+% more G3D Mark for each dollar spent, at 2.1 vs 0 G3D/$ ($1,269 MSRP vs Unknown MSRP).
  • 50% more VRAM for high-resolution textures and newer games (3 GB vs 2 GB).

Trade-offs

  • Very weak future-proofing: 2013-era hardware with 3 GB of VRAM is already obsolete for modern gaming and is hard to recommend today.
  • 128.6% higher power demand at 80W vs 35W.

Radeon Pro 450

2016

Why buy it

  • Draws 35W instead of 80W, a 45W reduction.
  • More future proof: GCN 4.0 (2016−2020) on 14nm with a newer platform for upcoming games.

Trade-offs

  • Less VRAM, with 2 GB vs 3 GB for high-resolution textures and newer games.
  • Very weak future-proofing: 2016-era hardware with 2 GB of VRAM is already obsolete for modern gaming and is hard to recommend today.
  • Lower G3D Mark per dollar, at 0 vs 2.1 G3D/$ (Unknown MSRP vs $1,269 MSRP).

Quick Answers

So, is Radeon Pro 450 better than Quadro K4000?
Yes, but this is not really about a huge raw performance gap. The broader synthetic picture is also very close at 2,719 vs 2,723 in G3D Mark. The bigger reason to prefer Radeon Pro 450 is the overall package: you are getting a newer generation, FSR upscaling, plus much lower power draw (35W vs 80W).
Which one is more future-proof for 2026 and beyond?
Quadro K4000 is the more future-proof choice for 2026 and beyond. You are getting more VRAM at 3 GB instead of 2 GB and the stronger feature stack with no meaningful modern upscaling stack instead of FSR upscaling. That extra memory headroom makes it the safer pick for newer games, heavier textures, and higher settings over time.
Which one is the smarter buy today, not just the cheaper card?
Radeon Pro 450 is the smarter buy by a wide margin. Radeon Pro 450 is priced in an unclear MSRP range at an unclear MSRP versus $1,269 MSRP, and you are getting 0.1% higher G3D Mark. Quadro K4000 really only makes sense now as a very cheap stopgap or a used-market placeholder.
When does Quadro K4000 make more sense than Radeon Pro 450?
Yes. Quadro K4000 is still an excellent gaming GPU in 2026: it is still comfortable for 1080p and decent for 1440p, though 4K is more situational. It makes more sense if your priority is future-proofing and staying closer to $1,269 MSRP more than squeezing out the extra headroom of Radeon Pro 450. The trade-off is that Radeon Pro 450 currently gives you 0.1% higher G3D Mark. Quadro K4000 still holds the G3D-per-dollar lead, so the performance win comes with a real value premium.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetQuadro K4000Radeon Pro 450
1080p
low32 FPS37 FPS
medium21 FPS22 FPS
high14 FPS16 FPS
ultra8 FPS9 FPS
1440p
low25 FPS25 FPS
medium15 FPS15 FPS
high8 FPS8 FPS
ultra4 FPS4 FPS
4K
low9 FPS9 FPS
medium6 FPS6 FPS
high4 FPS4 FPS
ultra3 FPS3 FPS
Counter-Strike 2

Counter-Strike 2

PresetQuadro K4000Radeon Pro 450
1080p
low39 FPS45 FPS
medium19 FPS24 FPS
high14 FPS17 FPS
ultra9 FPS11 FPS
1440p
low20 FPS20 FPS
medium9 FPS12 FPS
high7 FPS8 FPS
ultra5 FPS6 FPS
4K
low6 FPS6 FPS
medium3 FPS4 FPS
high3 FPS3 FPS
ultra2 FPS2 FPS
League of Legends

League of Legends

PresetQuadro K4000Radeon Pro 450
1080p
low122 FPS123 FPS
medium98 FPS98 FPS
high82 FPS82 FPS
ultra61 FPS61 FPS
1440p
low92 FPS92 FPS
medium73 FPS74 FPS
high61 FPS61 FPS
ultra46 FPS46 FPS
4K
low61 FPS61 FPS
medium49 FPS49 FPS
high41 FPS41 FPS
ultra31 FPS31 FPS
Valorant

Valorant

PresetQuadro K4000Radeon Pro 450
1080p
low122 FPS123 FPS
medium98 FPS98 FPS
high82 FPS82 FPS
ultra61 FPS61 FPS
1440p
low75 FPS92 FPS
medium61 FPS74 FPS
high52 FPS61 FPS
ultra35 FPS46 FPS
4K
low39 FPS59 FPS
medium30 FPS44 FPS
high26 FPS35 FPS
ultra17 FPS25 FPS

Technical Specifications

Side-by-side comparison of Quadro K4000 and Radeon Pro 450

NVIDIA

Quadro K4000

The Quadro K4000 is manufactured by NVIDIA. It was released in March 1 2013. It features the Kepler architecture. The core clock speed is 810 MHz. It has 768 shading units. The thermal design power (TDP) is 80W. Manufactured using 28 nm process technology. G3D Mark benchmark score: 2,719 points. Launch price was $1,269.

AMD

Radeon Pro 450

The Radeon Pro 450 is manufactured by AMD. It was released in October 30 2016. It features the GCN 4.0 architecture. The core clock speed is 800 MHz. It has 640 shading units. The thermal design power (TDP) is 35W. Manufactured using 14 nm process technology. G3D Mark benchmark score: 2,723 points.

Graphics Performance

The Quadro K4000 scores 2,719 and the Radeon Pro 450 reaches 2,723 in the G3D Mark benchmark — just a 0.1% difference, making them near-identical in rasterization performance. The Quadro K4000 is built on Kepler while the Radeon Pro 450 uses GCN 4.0, both on 28 nm vs 14 nm. Shader units: 768 (Quadro K4000) vs 640 (Radeon Pro 450). Raw compute: 1.244 TFLOPS (Quadro K4000) vs 1.024 TFLOPS (Radeon Pro 450).

FeatureQuadro K4000Radeon Pro 450
G3D Mark Score
2,719
2,723
Architecture
Kepler
GCN 4.0
Process Node
28 nm
14 nm
Shading Units
768+20%
640
Compute (TFLOPS)
1.244 TFLOPS+21%
1.024 TFLOPS
ROPs
24+50%
16
TMUs
64+60%
40
L1 Cache
64 KB
160 KB+150%
L2 Cache
0.38 MB
1 MB+163%

Advanced Features (DLSS/FSR)

FeatureQuadro K4000Radeon Pro 450
Upscaling Tech
Upscaling support
FSR Upscaling / FSR 4
Frame Generation
Not Supported
Not Supported
Ray Reconstruction
No
No
Low Latency
Standard
AMD Anti-Lag
💾

Video Memory (VRAM)

The Quadro K4000 comes with 3 GB of VRAM, while the Radeon Pro 450 has 2 GB. The Quadro K4000 offers 50% more capacity, crucial for higher resolutions and texture-heavy games. Bus width: 64-bit vs 64-bit. L2 Cache: 0.38 MB (Quadro K4000) vs 1 MB (Radeon Pro 450) — the Radeon Pro 450 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro K4000Radeon Pro 450
VRAM Capacity
3 GB+50%
2 GB
Memory Type
GDDR5
GDDR5
Bus Width
64-bit
64-bit
L2 Cache
0.38 MB
1 MB+163%
🔌

Power & Dimensions

The Quadro K4000 draws 80W versus the Radeon Pro 450's 35W — a 78.3% difference. The Radeon Pro 450 is more power-efficient. Recommended PSU: 350W (Quadro K4000) vs 350W (Radeon Pro 450). Power connectors: PCIe-powered vs PCIe-powered.

FeatureQuadro K4000Radeon Pro 450
TDP
80W
35W-56%
Recommended PSU
350W
350W
Power Connector
PCIe-powered
PCIe-powered
Length
1mm
Slots
0
Perf/Watt
34.0
77.8+129%
💰

Value Analysis

The Quadro K4000 launched at $1269 MSRP, while the Radeon Pro 450 launched at $0. The Radeon Pro 450 costs 100+% less ($1269 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 2.1 (Quadro K4000) vs Infinity (Radeon Pro 450) — the Radeon Pro 450 offers Infinity% better value. The Radeon Pro 450 is the newer GPU (2016 vs 2013).

FeatureQuadro K4000Radeon Pro 450
MSRP
$1269
$0-100%
Performance per Dollar
2.1
Infinity
Codename
GK106
Baffin
Release
March 1 2013
October 30 2016
Ranking
#613
#612