
Quadro RTX 4000 (Mobile)
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Radeon Instinct MI60
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Performance Spectrum - GPU
About G3D Mark
G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.
Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook
This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.
Quadro RTX 4000 (Mobile)
2021Why buy it
- ✅Access to a newer frame-generation stack with DLSS 3.5 + Frame Generation (2023).
- ✅More future proof: Turing (2018−2022) on 12nm with a newer platform for upcoming games.
- ✅Draws 40W instead of 300W, a 260W reduction.
Trade-offs
- ❌Lower average FPS than Radeon Instinct MI60 across 50 tracked games in our benchmark data.
- ❌Lower G3D Mark per dollar, at 0 vs 1.9 G3D/$ (Unknown MSRP vs $6,000 MSRP).
Radeon Instinct MI60
2018Why buy it
- ✅60.4% more average FPS across 50 tracked games in our benchmark data.
- ✅Delivers 100+% more G3D Mark for each dollar spent, at 1.9 vs 0 G3D/$ ($6,000 MSRP vs Unknown MSRP).
Trade-offs
- ❌No equivalent frame-generation stack like DLSS 3.5 + Frame Generation (2023).
- ❌Limited future-proofing: older hardware, 8 GB of VRAM, and weaker feature support mean it will age faster in upcoming AAA games.
- ❌650% higher power demand at 300W vs 40W.
Quadro RTX 4000 (Mobile)
2021Radeon Instinct MI60
2018Why buy it
- ✅Access to a newer frame-generation stack with DLSS 3.5 + Frame Generation (2023).
- ✅More future proof: Turing (2018−2022) on 12nm with a newer platform for upcoming games.
- ✅Draws 40W instead of 300W, a 260W reduction.
Why buy it
- ✅60.4% more average FPS across 50 tracked games in our benchmark data.
- ✅Delivers 100+% more G3D Mark for each dollar spent, at 1.9 vs 0 G3D/$ ($6,000 MSRP vs Unknown MSRP).
Trade-offs
- ❌Lower average FPS than Radeon Instinct MI60 across 50 tracked games in our benchmark data.
- ❌Lower G3D Mark per dollar, at 0 vs 1.9 G3D/$ (Unknown MSRP vs $6,000 MSRP).
Trade-offs
- ❌No equivalent frame-generation stack like DLSS 3.5 + Frame Generation (2023).
- ❌Limited future-proofing: older hardware, 8 GB of VRAM, and weaker feature support mean it will age faster in upcoming AAA games.
- ❌650% higher power demand at 300W vs 40W.
Quick Answers
So, is Quadro RTX 4000 (Mobile) better than Radeon Instinct MI60?
Which one is more future-proof for 2026 and beyond?
Which one is the smarter buy today, not just the cheaper card?
Is Radeon Instinct MI60 still worth buying for gaming in 2026?
Games Benchmarks
Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.
Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2
| Preset | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| 1080p | ||
| low | 104 FPS | 137 FPS |
| medium | 87 FPS | 117 FPS |
| high | 73 FPS | 101 FPS |
| ultra | 49 FPS | 70 FPS |
| 1440p | ||
| low | 90 FPS | 108 FPS |
| medium | 74 FPS | 89 FPS |
| high | 54 FPS | 73 FPS |
| ultra | 36 FPS | 51 FPS |
| 4K | ||
| low | 36 FPS | 50 FPS |
| medium | 32 FPS | 43 FPS |
| high | 20 FPS | 33 FPS |
| ultra | 17 FPS | 28 FPS |

Counter-Strike 2
| Preset | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| 1080p | ||
| low | 108 FPS | 316 FPS |
| medium | 85 FPS | 274 FPS |
| high | 66 FPS | 224 FPS |
| ultra | 51 FPS | 180 FPS |
| 1440p | ||
| low | 80 FPS | 214 FPS |
| medium | 61 FPS | 185 FPS |
| high | 48 FPS | 159 FPS |
| ultra | 36 FPS | 126 FPS |
| 4K | ||
| low | 49 FPS | 101 FPS |
| medium | 39 FPS | 85 FPS |
| high | 30 FPS | 73 FPS |
| ultra | 21 FPS | 56 FPS |

League of Legends
| Preset | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| 1080p | ||
| low | 410 FPS | 524 FPS |
| medium | 348 FPS | 419 FPS |
| high | 276 FPS | 349 FPS |
| ultra | 250 FPS | 262 FPS |
| 1440p | ||
| low | 306 FPS | 393 FPS |
| medium | 261 FPS | 314 FPS |
| high | 202 FPS | 262 FPS |
| ultra | 169 FPS | 196 FPS |
| 4K | ||
| low | 196 FPS | 262 FPS |
| medium | 171 FPS | 209 FPS |
| high | 120 FPS | 175 FPS |
| ultra | 80 FPS | 131 FPS |

Valorant
| Preset | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| 1080p | ||
| low | 220 FPS | 276 FPS |
| medium | 185 FPS | 237 FPS |
| high | 146 FPS | 202 FPS |
| ultra | 122 FPS | 164 FPS |
| 1440p | ||
| low | 167 FPS | 211 FPS |
| medium | 142 FPS | 186 FPS |
| high | 107 FPS | 158 FPS |
| ultra | 87 FPS | 126 FPS |
| 4K | ||
| low | 92 FPS | 125 FPS |
| medium | 70 FPS | 108 FPS |
| high | 56 FPS | 85 FPS |
| ultra | 42 FPS | 68 FPS |
Technical Specifications
Side-by-side comparison of Quadro RTX 4000 (Mobile) and Radeon Instinct MI60

Quadro RTX 4000 (Mobile)
Quadro RTX 4000 (Mobile)
The Quadro RTX 4000 (Mobile) is manufactured by NVIDIA. It was released in April 12 2021. It features the Turing architecture. The core clock ranges from 780 MHz to 1410 MHz. It has 896 shading units. The thermal design power (TDP) is 40W. Manufactured using 12 nm process technology. G3D Mark benchmark score: 11,715 points.

Radeon Instinct MI60
Radeon Instinct MI60
The Radeon Instinct MI60 is manufactured by AMD. It was released in November 18 2018. It features the GCN 5.1 architecture. The core clock ranges from 1200 MHz to 1800 MHz. It has 4096 shading units. The thermal design power (TDP) is 300W. Manufactured using 7 nm process technology. G3D Mark benchmark score: 11,638 points.
Graphics Performance
The Quadro RTX 4000 (Mobile) scores 11,715 and the Radeon Instinct MI60 reaches 11,638 in the G3D Mark benchmark — just a 0.7% difference, making them near-identical in rasterization performance. The Quadro RTX 4000 (Mobile) is built on Turing while the Radeon Instinct MI60 uses GCN 5.1, both on 12 nm vs 7 nm. Shader units: 896 (Quadro RTX 4000 (Mobile)) vs 4,096 (Radeon Instinct MI60). Raw compute: 2.527 TFLOPS (Quadro RTX 4000 (Mobile)) vs 14.75 TFLOPS (Radeon Instinct MI60). Boost clocks: 1410 MHz vs 1800 MHz.
| Feature | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| G3D Mark Score | 11,715 | 11,638 |
| Architecture | Turing | GCN 5.1 |
| Process Node | 12 nm | 7 nm |
| Shading Units | 896 | 4096+357% |
| Compute (TFLOPS) | 2.527 TFLOPS | 14.75 TFLOPS+484% |
| Boost Clock | 1410 MHz | 1800 MHz+28% |
| ROPs | 32 | 64+100% |
| TMUs | 56 | 256+357% |
| L1 Cache | 0.88 MB | 1 MB+14% |
| L2 Cache | 1 MB | 4 MB+300% |
Advanced Features (DLSS/FSR)
A critical advantage for the Quadro RTX 4000 (Mobile) is support for DLSS 3.5 + Frame Generation. This allows it to generate entire frames using AI/Algorithms, essentially doubling the frame rate in CPU-bound scenarios or heavy ray-tracing titles. The Radeon Instinct MI60 lacks specific hardware/driver support for this native frame generation tier.The Quadro RTX 4000 (Mobile) gives access to NVIDIA DLSS (Deep Learning Super Sampling), widely regarding as the superior upscaling method for image quality. The Radeon Instinct MI60 relies on FSR (FidelityFX Super Resolution), which is capable but generally slightly noisier than DLSS in motion.
| Feature | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| Upscaling Tech | DLSS 3.5 Super Resolution | FSR Upscaling / FSR 4 |
| Frame Generation | DLSS 3.5 + Frame Generation | Not Supported |
| Ray Reconstruction | Yes (DLSS 3.5) | No |
| Low Latency | NVIDIA Reflex | AMD Anti-Lag |
Video Memory (VRAM)
Both cards feature 8 GB of GDDR6. Bus width: 256-bit vs 128-bit. L2 Cache: 1 MB (Quadro RTX 4000 (Mobile)) vs 4 MB (Radeon Instinct MI60) — the Radeon Instinct MI60 has significantly larger on-die cache to reduce VRAM reliance.
| Feature | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| VRAM Capacity | 8 GB | 8 GB |
| Memory Type | GDDR6 | GDDR6 |
| Bus Width | 256-bit+100% | 128-bit |
| L2 Cache | 1 MB | 4 MB+300% |
Display & API Support
DirectX support: 12.2 (Quadro RTX 4000 (Mobile)) vs 12.1 (Radeon Instinct MI60). Vulkan: 1.1 vs 1.3. OpenGL: 4.6 vs 4.5. Maximum simultaneous displays: 4 vs 1.
| Feature | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| DirectX | 12.2 | 12.1 |
| Vulkan | 1.1 | 1.3+18% |
| OpenGL | 4.6+2% | 4.5 |
| Max Displays | 4+300% | 1 |
Media & Encoding
Hardware encoder: 7th Gen NVENC (Quadro RTX 4000 (Mobile)) vs VCE 4.1 (Radeon Instinct MI60). Decoder: 5th Gen NVDEC vs UVD 7.2. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro RTX 4000 (Mobile)) vs MPEG-2,H.264,HEVC,VP9 (Radeon Instinct MI60).
| Feature | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| Encoder | 7th Gen NVENC | VCE 4.1 |
| Decoder | 5th Gen NVDEC | UVD 7.2 |
| Codecs | MPEG-2,H.264,HEVC,VP9 | MPEG-2,H.264,HEVC,VP9 |
Power & Dimensions
The Quadro RTX 4000 (Mobile) draws 40W versus the Radeon Instinct MI60's 300W — a 152.9% difference. The Quadro RTX 4000 (Mobile) is more power-efficient. Recommended PSU: 500W (Quadro RTX 4000 (Mobile)) vs 500W (Radeon Instinct MI60). Power connectors: PCIe-powered vs PCIe-powered. Card length: 0mm vs 267mm, occupying 0 vs 2 slots. Typical load temperature: 85°C vs 85°C.
| Feature | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| TDP | 40W-87% | 300W |
| Recommended PSU | 500W | 500W |
| Power Connector | PCIe-powered | PCIe-powered |
| Length | 0mm | 267mm |
| Height | 0mm | 111mm |
| Slots | 0-100% | 2 |
| Temp (Load) | 85°C | 85°C |
| Perf/Watt | 292.9+655% | 38.8 |
Value Analysis
The Quadro RTX 4000 (Mobile) is the newer GPU (2021 vs 2018).
| Feature | Quadro RTX 4000 (Mobile) | Radeon Instinct MI60 |
|---|---|---|
| MSRP | — | $6000 |
| Codename | TU117 | Vega 20 |
| Release | April 12 2021 | November 18 2018 |
| Ranking | #354 | #232 |
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