Quadro RTX 4000 (Mobile) vs Radeon Instinct MI60

NVIDIA

Quadro RTX 4000 (Mobile)

2021Core: 780 MHzBoost: 1410 MHz

Popular choices:

VS
AMD

Radeon Instinct MI60

2018Core: 1200 MHzBoost: 1800 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Quadro RTX 4000 (Mobile)

2021

Why buy it

  • Access to a newer frame-generation stack with DLSS 3.5 + Frame Generation (2023).
  • More future proof: Turing (2018−2022) on 12nm with a newer platform for upcoming games.
  • Draws 40W instead of 300W, a 260W reduction.

Trade-offs

  • Lower average FPS than Radeon Instinct MI60 across 50 tracked games in our benchmark data.
  • Lower G3D Mark per dollar, at 0 vs 1.9 G3D/$ (Unknown MSRP vs $6,000 MSRP).

Radeon Instinct MI60

2018

Why buy it

  • 60.4% more average FPS across 50 tracked games in our benchmark data.
  • Delivers 100+% more G3D Mark for each dollar spent, at 1.9 vs 0 G3D/$ ($6,000 MSRP vs Unknown MSRP).

Trade-offs

  • No equivalent frame-generation stack like DLSS 3.5 + Frame Generation (2023).
  • Limited future-proofing: older hardware, 8 GB of VRAM, and weaker feature support mean it will age faster in upcoming AAA games.
  • 650% higher power demand at 300W vs 40W.

Quick Answers

So, is Quadro RTX 4000 (Mobile) better than Radeon Instinct MI60?
Yes. Quadro RTX 4000 (Mobile) is the better GPU overall here. You are getting 0.7% higher PassMark G3D performance and DLSS 3.5 + Frame Generation. It also comes from 2021 instead of 2018, which helps its case as the more complete modern gaming card.
Which one is more future-proof for 2026 and beyond?
Quadro RTX 4000 (Mobile) is the more future-proof choice for 2026 and beyond. You are getting a newer 2021 generation instead of 2018 and better frame-generation support with DLSS 3.5 + Frame Generation (2023) instead of FSR upscaling. That broader feature stack should age better as more games lean on modern upscaling and frame-generation support.
Which one is the smarter buy today, not just the cheaper card?
Quadro RTX 4000 (Mobile) is priced in an unclear MSRP range at an unclear MSRP versus $6,000 MSRP, and you are getting lower estimated average FPS across 50 tracked games in our benchmark data and 0.7% higher G3D Mark. Radeon Instinct MI60 still holds the G3D-per-dollar lead, so the performance win comes with a real value premium. If you are comfortable paying the premium for the stronger gaming result, Quadro RTX 4000 (Mobile) is the one to buy. If staying closer to budget matters more, Radeon Instinct MI60 still makes more sense on price alone, but the performance trade-off is much harder to justify by current standards.
Is Radeon Instinct MI60 still worth buying for gaming in 2026?
Yes. Radeon Instinct MI60 is still a strong gaming GPU in 2026: it is still comfortable for 1080p and decent for 1440p, though 4K is more situational. This mostly comes down to price. If you want to stay closer to $6,000 MSRP, it remains a strong choice; if you are comfortable paying more, Quadro RTX 4000 (Mobile) earns that extra money with a clearly stronger gaming result and a more complete overall package.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetQuadro RTX 4000 (Mobile)Radeon Instinct MI60
1080p
low104 FPS137 FPS
medium87 FPS117 FPS
high73 FPS101 FPS
ultra49 FPS70 FPS
1440p
low90 FPS108 FPS
medium74 FPS89 FPS
high54 FPS73 FPS
ultra36 FPS51 FPS
4K
low36 FPS50 FPS
medium32 FPS43 FPS
high20 FPS33 FPS
ultra17 FPS28 FPS
Counter-Strike 2

Counter-Strike 2

PresetQuadro RTX 4000 (Mobile)Radeon Instinct MI60
1080p
low108 FPS316 FPS
medium85 FPS274 FPS
high66 FPS224 FPS
ultra51 FPS180 FPS
1440p
low80 FPS214 FPS
medium61 FPS185 FPS
high48 FPS159 FPS
ultra36 FPS126 FPS
4K
low49 FPS101 FPS
medium39 FPS85 FPS
high30 FPS73 FPS
ultra21 FPS56 FPS
League of Legends

League of Legends

PresetQuadro RTX 4000 (Mobile)Radeon Instinct MI60
1080p
low410 FPS524 FPS
medium348 FPS419 FPS
high276 FPS349 FPS
ultra250 FPS262 FPS
1440p
low306 FPS393 FPS
medium261 FPS314 FPS
high202 FPS262 FPS
ultra169 FPS196 FPS
4K
low196 FPS262 FPS
medium171 FPS209 FPS
high120 FPS175 FPS
ultra80 FPS131 FPS
Valorant

Valorant

PresetQuadro RTX 4000 (Mobile)Radeon Instinct MI60
1080p
low220 FPS276 FPS
medium185 FPS237 FPS
high146 FPS202 FPS
ultra122 FPS164 FPS
1440p
low167 FPS211 FPS
medium142 FPS186 FPS
high107 FPS158 FPS
ultra87 FPS126 FPS
4K
low92 FPS125 FPS
medium70 FPS108 FPS
high56 FPS85 FPS
ultra42 FPS68 FPS

Technical Specifications

Side-by-side comparison of Quadro RTX 4000 (Mobile) and Radeon Instinct MI60

NVIDIA

Quadro RTX 4000 (Mobile)

The Quadro RTX 4000 (Mobile) is manufactured by NVIDIA. It was released in April 12 2021. It features the Turing architecture. The core clock ranges from 780 MHz to 1410 MHz. It has 896 shading units. The thermal design power (TDP) is 40W. Manufactured using 12 nm process technology. G3D Mark benchmark score: 11,715 points.

AMD

Radeon Instinct MI60

The Radeon Instinct MI60 is manufactured by AMD. It was released in November 18 2018. It features the GCN 5.1 architecture. The core clock ranges from 1200 MHz to 1800 MHz. It has 4096 shading units. The thermal design power (TDP) is 300W. Manufactured using 7 nm process technology. G3D Mark benchmark score: 11,638 points.

Graphics Performance

The Quadro RTX 4000 (Mobile) scores 11,715 and the Radeon Instinct MI60 reaches 11,638 in the G3D Mark benchmark — just a 0.7% difference, making them near-identical in rasterization performance. The Quadro RTX 4000 (Mobile) is built on Turing while the Radeon Instinct MI60 uses GCN 5.1, both on 12 nm vs 7 nm. Shader units: 896 (Quadro RTX 4000 (Mobile)) vs 4,096 (Radeon Instinct MI60). Raw compute: 2.527 TFLOPS (Quadro RTX 4000 (Mobile)) vs 14.75 TFLOPS (Radeon Instinct MI60). Boost clocks: 1410 MHz vs 1800 MHz.

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
G3D Mark Score
11,715
11,638
Architecture
Turing
GCN 5.1
Process Node
12 nm
7 nm
Shading Units
896
4096+357%
Compute (TFLOPS)
2.527 TFLOPS
14.75 TFLOPS+484%
Boost Clock
1410 MHz
1800 MHz+28%
ROPs
32
64+100%
TMUs
56
256+357%
L1 Cache
0.88 MB
1 MB+14%
L2 Cache
1 MB
4 MB+300%

Advanced Features (DLSS/FSR)

A critical advantage for the Quadro RTX 4000 (Mobile) is support for DLSS 3.5 + Frame Generation. This allows it to generate entire frames using AI/Algorithms, essentially doubling the frame rate in CPU-bound scenarios or heavy ray-tracing titles. The Radeon Instinct MI60 lacks specific hardware/driver support for this native frame generation tier.The Quadro RTX 4000 (Mobile) gives access to NVIDIA DLSS (Deep Learning Super Sampling), widely regarding as the superior upscaling method for image quality. The Radeon Instinct MI60 relies on FSR (FidelityFX Super Resolution), which is capable but generally slightly noisier than DLSS in motion.

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
Upscaling Tech
DLSS 3.5 Super Resolution
FSR Upscaling / FSR 4
Frame Generation
DLSS 3.5 + Frame Generation
Not Supported
Ray Reconstruction
Yes (DLSS 3.5)
No
Low Latency
NVIDIA Reflex
AMD Anti-Lag
💾

Video Memory (VRAM)

Both cards feature 8 GB of GDDR6. Bus width: 256-bit vs 128-bit. L2 Cache: 1 MB (Quadro RTX 4000 (Mobile)) vs 4 MB (Radeon Instinct MI60) — the Radeon Instinct MI60 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
VRAM Capacity
8 GB
8 GB
Memory Type
GDDR6
GDDR6
Bus Width
256-bit+100%
128-bit
L2 Cache
1 MB
4 MB+300%
🖥️

Display & API Support

DirectX support: 12.2 (Quadro RTX 4000 (Mobile)) vs 12.1 (Radeon Instinct MI60). Vulkan: 1.1 vs 1.3. OpenGL: 4.6 vs 4.5. Maximum simultaneous displays: 4 vs 1.

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
DirectX
12.2
12.1
Vulkan
1.1
1.3+18%
OpenGL
4.6+2%
4.5
Max Displays
4+300%
1
🎬

Media & Encoding

Hardware encoder: 7th Gen NVENC (Quadro RTX 4000 (Mobile)) vs VCE 4.1 (Radeon Instinct MI60). Decoder: 5th Gen NVDEC vs UVD 7.2. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro RTX 4000 (Mobile)) vs MPEG-2,H.264,HEVC,VP9 (Radeon Instinct MI60).

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
Encoder
7th Gen NVENC
VCE 4.1
Decoder
5th Gen NVDEC
UVD 7.2
Codecs
MPEG-2,H.264,HEVC,VP9
MPEG-2,H.264,HEVC,VP9
🔌

Power & Dimensions

The Quadro RTX 4000 (Mobile) draws 40W versus the Radeon Instinct MI60's 300W — a 152.9% difference. The Quadro RTX 4000 (Mobile) is more power-efficient. Recommended PSU: 500W (Quadro RTX 4000 (Mobile)) vs 500W (Radeon Instinct MI60). Power connectors: PCIe-powered vs PCIe-powered. Card length: 0mm vs 267mm, occupying 0 vs 2 slots. Typical load temperature: 85°C vs 85°C.

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
TDP
40W-87%
300W
Recommended PSU
500W
500W
Power Connector
PCIe-powered
PCIe-powered
Length
0mm
267mm
Height
0mm
111mm
Slots
0-100%
2
Temp (Load)
85°C
85°C
Perf/Watt
292.9+655%
38.8
💰

Value Analysis

The Quadro RTX 4000 (Mobile) is the newer GPU (2021 vs 2018).

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
MSRP
$6000
Codename
TU117
Vega 20
Release
April 12 2021
November 18 2018
Ranking
#354
#232