
Quadro P4000
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Radeon Instinct MI60
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Performance Spectrum - GPU
About G3D Mark
G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.
Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook
This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.
Quadro P4000
2017Why buy it
- ✅Costs $5,185 less on MSRP ($815 MSRP vs $6,000 MSRP).
- ✅Delivers 623.1% more G3D Mark for each dollar spent, at 14.0 vs 1.9 G3D/$ ($815 MSRP vs $6,000 MSRP).
- ✅Draws 105W instead of 300W, a 195W reduction.
- ✅Measures 241mm instead of 267mm, a 26mm shorter card that is more SFF-friendly.
Trade-offs
- ❌Lower average FPS than Radeon Instinct MI60 across 50 tracked games in our benchmark data.
- ❌Poor future-proofing: 2017-era hardware with 8 GB of VRAM is already a legacy-tier option for modern games.
Radeon Instinct MI60
2018Why buy it
- ✅25.2% more average FPS across 50 tracked games in our benchmark data.
- ✅Less risky long-term buy than Quadro P4000: it remains the more sensible modern option while Quadro P4000 is already legacy-tier future-proofing.
- ✅More future proof: GCN 5.1 (2018−2022) on 7nm with a newer platform for upcoming games.
Trade-offs
- ❌Limited future-proofing: older hardware, 8 GB of VRAM, and weaker feature support mean it will age faster in upcoming AAA games.
- ❌636.2% HIGHER MSRP$6,000 MSRPvs$815 MSRP
- ❌Lower G3D Mark per dollar, at 1.9 vs 14.0 G3D/$ ($6,000 MSRP vs $815 MSRP).
- ❌185.7% higher power demand at 300W vs 105W.
- ❌10.8% longer card at 267mm vs 241mm.
Quadro P4000
2017Radeon Instinct MI60
2018Why buy it
- ✅Costs $5,185 less on MSRP ($815 MSRP vs $6,000 MSRP).
- ✅Delivers 623.1% more G3D Mark for each dollar spent, at 14.0 vs 1.9 G3D/$ ($815 MSRP vs $6,000 MSRP).
- ✅Draws 105W instead of 300W, a 195W reduction.
- ✅Measures 241mm instead of 267mm, a 26mm shorter card that is more SFF-friendly.
Why buy it
- ✅25.2% more average FPS across 50 tracked games in our benchmark data.
- ✅Less risky long-term buy than Quadro P4000: it remains the more sensible modern option while Quadro P4000 is already legacy-tier future-proofing.
- ✅More future proof: GCN 5.1 (2018−2022) on 7nm with a newer platform for upcoming games.
Trade-offs
- ❌Lower average FPS than Radeon Instinct MI60 across 50 tracked games in our benchmark data.
- ❌Poor future-proofing: 2017-era hardware with 8 GB of VRAM is already a legacy-tier option for modern games.
Trade-offs
- ❌Limited future-proofing: older hardware, 8 GB of VRAM, and weaker feature support mean it will age faster in upcoming AAA games.
- ❌636.2% HIGHER MSRP$6,000 MSRPvs$815 MSRP
- ❌Lower G3D Mark per dollar, at 1.9 vs 14.0 G3D/$ ($6,000 MSRP vs $815 MSRP).
- ❌185.7% higher power demand at 300W vs 105W.
- ❌10.8% longer card at 267mm vs 241mm.
Quick Answers
So, is Radeon Instinct MI60 better than Quadro P4000?
Which one is more future-proof for 2026 and beyond?
Which one is the smarter buy today, not just the cheaper card?
Is Quadro P4000 still worth buying for gaming in 2026?
Games Benchmarks
Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.
Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2
| Preset | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| 1080p | ||
| low | 111 FPS | 137 FPS |
| medium | 94 FPS | 117 FPS |
| high | 80 FPS | 101 FPS |
| ultra | 53 FPS | 70 FPS |
| 1440p | ||
| low | 94 FPS | 108 FPS |
| medium | 79 FPS | 89 FPS |
| high | 60 FPS | 73 FPS |
| ultra | 39 FPS | 51 FPS |
| 4K | ||
| low | 37 FPS | 50 FPS |
| medium | 34 FPS | 43 FPS |
| high | 22 FPS | 33 FPS |
| ultra | 18 FPS | 28 FPS |

Counter-Strike 2
| Preset | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| 1080p | ||
| low | 223 FPS | 316 FPS |
| medium | 190 FPS | 274 FPS |
| high | 146 FPS | 224 FPS |
| ultra | 117 FPS | 180 FPS |
| 1440p | ||
| low | 164 FPS | 214 FPS |
| medium | 139 FPS | 185 FPS |
| high | 111 FPS | 159 FPS |
| ultra | 88 FPS | 126 FPS |
| 4K | ||
| low | 96 FPS | 101 FPS |
| medium | 80 FPS | 85 FPS |
| high | 67 FPS | 73 FPS |
| ultra | 51 FPS | 56 FPS |

League of Legends
| Preset | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| 1080p | ||
| low | 514 FPS | 524 FPS |
| medium | 412 FPS | 419 FPS |
| high | 343 FPS | 349 FPS |
| ultra | 257 FPS | 262 FPS |
| 1440p | ||
| low | 386 FPS | 393 FPS |
| medium | 309 FPS | 314 FPS |
| high | 257 FPS | 262 FPS |
| ultra | 193 FPS | 196 FPS |
| 4K | ||
| low | 257 FPS | 262 FPS |
| medium | 206 FPS | 209 FPS |
| high | 171 FPS | 175 FPS |
| ultra | 129 FPS | 131 FPS |

Valorant
| Preset | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| 1080p | ||
| low | 250 FPS | 276 FPS |
| medium | 219 FPS | 237 FPS |
| high | 176 FPS | 202 FPS |
| ultra | 147 FPS | 164 FPS |
| 1440p | ||
| low | 191 FPS | 211 FPS |
| medium | 166 FPS | 186 FPS |
| high | 130 FPS | 158 FPS |
| ultra | 105 FPS | 126 FPS |
| 4K | ||
| low | 101 FPS | 125 FPS |
| medium | 83 FPS | 108 FPS |
| high | 66 FPS | 85 FPS |
| ultra | 51 FPS | 68 FPS |
Technical Specifications
Side-by-side comparison of Quadro P4000 and Radeon Instinct MI60

Quadro P4000
Quadro P4000
The Quadro P4000 is manufactured by NVIDIA. It was released in February 6 2017. It features the Pascal architecture. The core clock ranges from 1202 MHz to 1480 MHz. It has 1792 shading units. The thermal design power (TDP) is 105W. Manufactured using 16 nm process technology. G3D Mark benchmark score: 11,431 points. Launch price was $815.

Radeon Instinct MI60
Radeon Instinct MI60
The Radeon Instinct MI60 is manufactured by AMD. It was released in November 18 2018. It features the GCN 5.1 architecture. The core clock ranges from 1200 MHz to 1800 MHz. It has 4096 shading units. The thermal design power (TDP) is 300W. Manufactured using 7 nm process technology. G3D Mark benchmark score: 11,638 points.
Graphics Performance
The Quadro P4000 scores 11,431 and the Radeon Instinct MI60 reaches 11,638 in the G3D Mark benchmark — just a 1.8% difference, making them near-identical in rasterization performance. The Quadro P4000 is built on Pascal while the Radeon Instinct MI60 uses GCN 5.1, both on 16 nm vs 7 nm. Shader units: 1,792 (Quadro P4000) vs 4,096 (Radeon Instinct MI60). Raw compute: 5.304 TFLOPS (Quadro P4000) vs 14.75 TFLOPS (Radeon Instinct MI60). Boost clocks: 1480 MHz vs 1800 MHz.
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| G3D Mark Score | 11,431 | 11,638+2% |
| Architecture | Pascal | GCN 5.1 |
| Process Node | 16 nm | 7 nm |
| Shading Units | 1792 | 4096+129% |
| Compute (TFLOPS) | 5.304 TFLOPS | 14.75 TFLOPS+178% |
| Boost Clock | 1480 MHz | 1800 MHz+22% |
| ROPs | 64 | 64 |
| TMUs | 112 | 256+129% |
| L1 Cache | 0.66 MB | 1 MB+52% |
| L2 Cache | 2 MB | 4 MB+100% |
Advanced Features (DLSS/FSR)
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| Upscaling Tech | Upscaling support | FSR Upscaling / FSR 4 |
| Frame Generation | Not Supported | Not Supported |
| Ray Reconstruction | No | No |
| Low Latency | Standard | AMD Anti-Lag |
Video Memory (VRAM)
Both cards feature 8 GB of GDDR6. Bus width: 256-bit vs 128-bit. L2 Cache: 2 MB (Quadro P4000) vs 4 MB (Radeon Instinct MI60) — the Radeon Instinct MI60 has significantly larger on-die cache to reduce VRAM reliance.
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| VRAM Capacity | 8 GB | 8 GB |
| Memory Type | GDDR6 | GDDR6 |
| Bus Width | 256-bit+100% | 128-bit |
| L2 Cache | 2 MB | 4 MB+100% |
Display & API Support
DirectX support: 12.0 (Quadro P4000) vs 12.1 (Radeon Instinct MI60). Vulkan: 1.0 vs 1.3. OpenGL: 4.5 vs 4.5. Maximum simultaneous displays: 4 vs 1.
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| DirectX | 12.0 | 12.1 |
| Vulkan | 1.0 | 1.3+30% |
| OpenGL | 4.5 | 4.5 |
| Max Displays | 4+300% | 1 |
Media & Encoding
Hardware encoder: 6th Gen NVENC (Quadro P4000) vs VCE 4.1 (Radeon Instinct MI60). Decoder: PureVideo HD VP8 vs UVD 7.2. Supported codecs: MPEG-2,H.264,HEVC (Quadro P4000) vs MPEG-2,H.264,HEVC,VP9 (Radeon Instinct MI60).
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| Encoder | 6th Gen NVENC | VCE 4.1 |
| Decoder | PureVideo HD VP8 | UVD 7.2 |
| Codecs | MPEG-2,H.264,HEVC | MPEG-2,H.264,HEVC,VP9 |
Power & Dimensions
The Quadro P4000 draws 105W versus the Radeon Instinct MI60's 300W — a 96.3% difference. The Quadro P4000 is more power-efficient. Recommended PSU: 500W (Quadro P4000) vs 500W (Radeon Instinct MI60). Power connectors: PCIe-powered vs PCIe-powered. Card length: 241mm vs 267mm, occupying 1 vs 2 slots. Typical load temperature: 80°C vs 85°C.
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| TDP | 105W-65% | 300W |
| Recommended PSU | 500W | 500W |
| Power Connector | PCIe-powered | PCIe-powered |
| Length | 241mm | 267mm |
| Height | 111mm | 111mm |
| Slots | 1-50% | 2 |
| Temp (Load) | 80°C-6% | 85°C |
| Perf/Watt | 108.9+181% | 38.8 |
Value Analysis
The Quadro P4000 launched at $815 MSRP, while the Radeon Instinct MI60 launched at $6000. The Quadro P4000 costs 86.4% less ($5185 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 14.0 (Quadro P4000) vs 1.9 (Radeon Instinct MI60) — the Quadro P4000 offers 636.8% better value. The Radeon Instinct MI60 is the newer GPU (2018 vs 2017).
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| MSRP | $815-86% | $6000 |
| Performance per Dollar | 14.0+637% | 1.9 |
| Codename | GP104 | Vega 20 |
| Release | February 6 2017 | November 18 2018 |
| Ranking | #239 | #232 |
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