EPYC 7F72 vs EPYC 4545P

AMD

EPYC 7F72

24 Cores48 Thrd240 WWMax: 3.7 GHz2020

Popular choices:

VS
AMD

EPYC 4545P

16 Cores32 Thrd65 WWMax: 5.4 GHz2025

Popular choices:

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

EPYC 7F72

2020

Why buy it

  • +200% larger total L3 cache (192 MB vs 64 MB).
  • 357.1% more PCIe lanes (128 vs 28) for storage and expansion-heavy builds.

Trade-offs

  • Worse for gaming: lower average FPS than EPYC 4545P across 4 shared CPU benchmark tests.
  • Lower PassMark (52,840 vs 54,255).
  • Lower PassMark per dollar, at 24.8 vs 98.8 PassMark/$ ($2,131 MSRP vs $549 MSRP).
  • 269.2% higher power demand at 240W vs 65W.
  • Older platform position on SP3 with DDR4, while EPYC 4545P moves to AM5 and DDR5.

EPYC 4545P

2025

Why buy it

  • Better for gaming: +33.1% higher average FPS across 4 shared CPU benchmark tests.
  • Costs $1,582 less on MSRP ($549 MSRP vs $2,131 MSRP).
  • Delivers 298.6% more PassMark for each dollar spent, at 98.8 vs 24.8 PassMark/$ ($549 MSRP vs $2,131 MSRP).
  • Draws 65W instead of 240W, a 175W reduction.
  • Newer platform on AM5 with DDR5 support instead of SP3 and DDR4.

Trade-offs

  • Smaller total L3 cache (64 MB vs 192 MB).

Quick Answers

So, is EPYC 4545P better than EPYC 7F72?
Yes. EPYC 4545P is the better overall CPU here. You are getting a 33.1% average FPS lead across 4 shared CPU game tests in our data, 2.7% better PassMark, and the stronger long-term platform, which makes it the stronger all-around choice.
Which one is better for gaming?
If gaming is the priority, EPYC 4545P is the better pick here. According to our tests, it delivers 33.1% more average FPS across 4 shared CPU game tests.
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, EPYC 4545P is the better fit. You are getting 2.7% better PassMark, backed by 16 cores and 32 threads.
Which one is the smarter buy today, not just the cheaper CPU?
EPYC 4545P is the smarter buy today. EPYC 4545P is $1,582 cheaper on MSRP at $549 MSRP versus $2,131 MSRP, and it gives you a 33.1% average FPS lead across 4 shared CPU game tests in our data. It is also 298.6% better value on MSRP (98.8 vs 24.8 PassMark/$), so the better CPU is not just faster, it is also the cleaner value play on paper.
Which one is more future-proof for 2026 and beyond?
EPYC 4545P is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2025 vs 2020), a healthier platform with AM5 and DDR5 instead of SP3, more multi-core headroom with 16 cores / 32 threads instead of 24/48, and AVX-512 support for heavier modern compute workloads. That should give you a better long-term upgrade path for motherboard, RAM, and future CPU swaps.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Path of Exile 2

Path of Exile 2

PresetEPYC 7F72EPYC 4545P
1080p
low176 FPS286 FPS
medium148 FPS262 FPS
high130 FPS215 FPS
ultra102 FPS181 FPS
1440p
low151 FPS262 FPS
medium122 FPS218 FPS
high98 FPS167 FPS
ultra78 FPS148 FPS
4K
low71 FPS182 FPS
medium61 FPS151 FPS
high48 FPS115 FPS
ultra39 FPS102 FPS
Counter-Strike 2

Counter-Strike 2

PresetEPYC 7F72EPYC 4545P
1080p
low510 FPS674 FPS
medium449 FPS580 FPS
high341 FPS434 FPS
ultra273 FPS375 FPS
1440p
low418 FPS567 FPS
medium377 FPS506 FPS
high297 FPS392 FPS
ultra230 FPS312 FPS
4K
low260 FPS320 FPS
medium239 FPS289 FPS
high200 FPS255 FPS
ultra163 FPS219 FPS
League of Legends

League of Legends

PresetEPYC 7F72EPYC 4545P
1080p
low605 FPS850 FPS
medium495 FPS679 FPS
high452 FPS601 FPS
ultra388 FPS515 FPS
1440p
low520 FPS679 FPS
medium431 FPS543 FPS
high388 FPS469 FPS
ultra334 FPS398 FPS
4K
low388 FPS484 FPS
medium302 FPS401 FPS
high265 FPS360 FPS
ultra212 FPS302 FPS
Valorant

Valorant

PresetEPYC 7F72EPYC 4545P
1080p
low877 FPS1072 FPS
medium808 FPS966 FPS
high695 FPS843 FPS
ultra613 FPS760 FPS
1440p
low708 FPS842 FPS
medium626 FPS747 FPS
high535 FPS652 FPS
ultra458 FPS566 FPS
4K
low508 FPS619 FPS
medium460 FPS553 FPS
high404 FPS487 FPS
ultra349 FPS421 FPS

Technical Specifications

Side-by-side comparison of EPYC 7F72 and EPYC 4545P

AMD

EPYC 7F72

The EPYC 7F72 is manufactured by AMD. It was released in 14 April 2020 (5 years ago). It is based on the Zen 2 (2017−2020) architecture. It features 24 cores and 48 threads. Base frequency is 3.2 GHz, with boost up to 3.7 GHz. L3 cache: 192 MB (total). L2 cache: 512K (per core). Built on 7 nm, 14 nm process technology. Socket: SP3. Thermal design power (TDP): 240 Watt. Memory support: DDR4-3200. Passmark benchmark score: 52,840 points. Launch price was $2,450.

AMD

EPYC 4545P

The EPYC 4545P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 16 cores and 32 threads. Base frequency is 3 GHz, with boost up to 5.4 GHz. L3 cache: 64 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 65 Watt. Memory support: DDR5. Passmark benchmark score: 54,255 points. Launch price was $549.

Processing Power

The EPYC 7F72 packs 24 cores / 48 threads, while the EPYC 4545P offers 16 cores / 32 threads — the EPYC 7F72 has 8 more cores. Boost clocks reach 3.7 GHz on the EPYC 7F72 versus 5.4 GHz on the EPYC 4545P — a 37.4% clock advantage for the EPYC 4545P (base: 3.2 GHz vs 3 GHz). The EPYC 7F72 uses the Zen 2 (2017−2020) architecture (7 nm, 14 nm), while the EPYC 4545P uses Grado (2025) (4 nm). In PassMark, the EPYC 7F72 scores 52,840 against the EPYC 4545P's 54,255 — a 2.6% lead for the EPYC 4545P. L3 cache: 192 MB (total) on the EPYC 7F72 vs 64 MB (total) on the EPYC 4545P.

FeatureEPYC 7F72EPYC 4545P
Cores / Threads
24 / 48+50%
16 / 32
Boost Clock
3.7 GHz
5.4 GHz+46%
Base Clock
3.2 GHz+7%
3 GHz
L3 Cache
192 MB (total)+200%
64 MB (total)
L2 Cache
512K (per core)
1 MB (per core)+100%
Process
7 nm, 14 nm
4 nm-43%
Architecture
Zen 2 (2017−2020)
Grado (2025)
PassMark
52,840
54,255+3%
🧠

Memory & Platform

The EPYC 7F72 uses the SP3 socket (PCIe 4.0), while the EPYC 4545P uses AM5 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 3200 on the EPYC 7F72 versus 5600 on the EPYC 4545P — the EPYC 4545P supports 54.5% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7F72 supports up to 4096 of RAM compared to 192 182.1% more capacity for professional workloads. Memory channels: 8 (EPYC 7F72) vs 2 (EPYC 4545P). PCIe lanes: 128 (EPYC 7F72) vs 28 (EPYC 4545P) — the EPYC 7F72 offers 100 more lanes for additional GPUs or NVMe drives. Chipset compatibility: SP3 (EPYC 7F72) and AM5 (EPYC 4545P).

FeatureEPYC 7F72EPYC 4545P
Socket
SP3
AM5
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
3200
5600+75%
Max RAM Capacity
4096+2033%
192
RAM Channels
8+300%
2
ECC Support
Yes
Yes
PCIe Lanes
128+357%
28
🔧

Advanced Features

Only the EPYC 4545P has an unlocked multiplier for overclocking — a significant advantage for enthusiasts seeking extra performance. Only the EPYC 4545P supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: VT-x, VT-d (EPYC 7F72) vs VT-x, VT-d, AMD-V (EPYC 4545P). The EPYC 4545P includes integrated graphics (AMD Radeon Graphics), while the EPYC 7F72 requires a dedicated GPU. Direct competitor: EPYC 7F72 rivals Xeon Platinum 8260; EPYC 4545P rivals Ryzen 9 7900X.

FeatureEPYC 7F72EPYC 4545P
Integrated GPU
No
Yes
IGPU Model
None
AMD Radeon Graphics
Unlocked
No
Yes
AVX-512
No
Yes
Virtualization
VT-x, VT-d
VT-x, VT-d, AMD-V
💰

Value Analysis

The EPYC 7F72 launched at $2131 MSRP, while the EPYC 4545P debuted at $549. On MSRP ($2131 vs $549), the EPYC 4545P is $1582 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 7F72 delivers 24.8 pts/$ vs 98.8 pts/$ for the EPYC 4545P — making the EPYC 4545P the 119.8% better value option.

FeatureEPYC 7F72EPYC 4545P
MSRP
$2131
$549-74%
Performance per Dollar
24.8
98.8+298%
Release Date
2020
2025